Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy

Guo, M., Wu, Y., Hobson, C. M., Su, Y., Qian, S., Krueger, E., Christensen, R., Kroeschell, G., Bui, J., Chaw, M., Zhang, L., Liu, J., Hou, X., Han, X., Lu, Z., Ma, X., Zhovmer, A., Combs, C., Moyle, M. & Yemini, E. & 6 others, Liu, H., Liu, Z., Benedetto, A., La Riviere, P., Colón-Ramos, D. & Shroff, H., 2/01/2025, In: Nature Communications. 16, 1, 313.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Understanding exogenous factors and biological mechanisms for cognitive frailty: A multidisciplinary scoping review

Holland, C., Dravecz, N., Owens, L., Benedetto, A., Dias, I., Gow, A. & Broughton, S., 30/11/2024, In: Ageing Research Reviews. 101, 102461.

Research output: Contribution to Journal/Magazine › Review article › peer-review

Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy

Benedetto, A., 15/07/2024, In: Biorxiv.

Research output: Contribution to Journal/Magazine › Journal article

Creating 3D objects with integrated electronics via multiphoton fabrication in vitro and in vivo

Baldock, S., Kevin, P., Harper, G., Griffin, R., Genedy, H., Fong, J., Zhao, Z., Zhang, Z., Shen, Y., Lin, H., Au, C., Martin, J., Ashton, M., Haskew, M., Stewart, B., Efremova, O., Esfahani, R., Emsley, H., Appleby, J. & Cheneler, D. & 3 others, Cummings, D. M., Benedetto, A. & Hardy, J., 9/06/2023, In: Advanced Materials Technologies. 8, 11, 13 p., 2201274.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions

Zárate-Potes, A., Ali, I., Ribeiro Camacho, M., Brownless, H. & Benedetto, A., 10/05/2022, In: Frontiers in Microbiology. 13, 17 p., 853629.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

High-Throughput Screening of Microbial Isolates with Impact on Caenorhabditis elegans Health

Ali, I., Martin, J., Zárate-Potes, A. & Benedetto, A., 28/04/2022, In: Journal of Visualized Experiments. 2022, 182, e63860.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

BACE1 Overexpression Reduces SH-SY5Y Cell Viability Through a Mechanism Distinct from Amyloid-β Peptide Accumulation: Beta Prime-Mediated Competitive Depletion of sAβPPα

Owens, L., Bracewell, J., Benedetto, A., Dawson, N., Gaffney, C. & Parkin, E., 5/04/2022, In: Journal of Alzheimer's Disease. 86, 3, p. 1201-1220 20 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Gene therapy-mediated enhancement of protective protein expression for the treatment of Alzheimer's disease

Owens, L., Benedetto, A., Dawson, N., Gaffney, C. & Parkin, E., 15/02/2021, In: Brain Research. 1753, 12 p., 147264.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

New label-free automated survival assays reveal unexpected stress resistance patterns during C. elegans aging

Benedetto, A., Bambade, T., Au, C., Tullet, J. M. A., Monkhouse, J., Dang, H., Cetnar, K., Chan, B., Cabreiro, F. & Gems, D., 1/10/2019, In: Aging Cell. 18, 5, 10 p., e12998.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Autophagy promotes visceral aging in wild-type C. elegans

Benedetto, A. & Gems, D., 3/04/2019, In: Autophagy. 15, 4, p. 737-732 2 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Erratum: C. elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies (Current Biology (2018) 28(16) (2544–2556.e5), (S0960982218308261) (10.1016/j.cub.2018.06.035))

Ezcurra, M., Benedetto, A., Sornda, T., Gilliat, A. F., Au, C., Zhang, Q., van Schelt, S., Petrache, A. L., Wang, H., Guardia, Y. D. L., Bar-Nun, S., Tyler, E., Wakelam, M. J. & Gems, D., 22/10/2018, In: Current Biology. 28, 20, 1 p.

Research output: Contribution to Journal/Magazine › Comment/debate › peer-review

C. elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies

Ezcurra, M., Benedetto, A., Sornda, T., Gilliat, A. F., Au, C., Zhang, Q., van Schelt, S., Petrache, A. L., Wang, H., de la Guardia, Y., Bar-Nun, S., Tyler, E., Wakelam, M. J. & Gems, D., 20/08/2018, In: Current Biology. 28, 16, p. 2544-2556.e5 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A parthenogenetic quasi-program causes teratoma-like tumors during aging in wild-type C. elegans

Wang, H., Zhao, Y., Ezcurra, M., Benedetto, A., Gilliat, A. F., Hellberg, J., Ren, Z., Galimov, E. R., Athigapanich, T., Girstmair, J., Telford, M. J., Dolphin, C. T., Zhang, Z. & Gems, D., 13/06/2018, In: npj Aging and Mechanisms of Disease. 4, 1, 12 p., 6.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Rigor mortis-like process during organismal death in c. elegans

Galimov, E. R., Pryor, R. E., Poole, S. E., Benedetto, A., Pincus, Z. & Gems, D., 06/2018, In: Opera Medica et Physiologica. 4, p. 74 1 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Coupling of Rigor Mortis and Intestinal Necrosis during C. elegans Organismal Death

Galimov, E. R., Pryor, R. E., Poole, S. E., Benedetto, A., Pincus, Z. & Gems, D., 6/03/2018, In: Cell Reports. 22, 10, p. 2730-2741 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Autophagy-dependent gut-to-yolk biomass conversion generates visceral polymorbidity in aging C. elegans

Ezcurra, M., Benedetto, A., Sornda, T., Gilliat, A., Au, C., Zhang, Q., van Schelt, S., Petrache, A. L., de la Guardia, Y., Bar-Nun, S., Tyler, E., Wakelam, M. J. & Gems, D., 15/12/2017, In: Biorxiv.

Research output: Contribution to Journal/Magazine › Journal article

The SKN-1/Nrf2 transcription factor can protect against oxidative stress and increase lifespan in C. elegans by distinct mechanisms

Tullet, J. M. A., Green, J. W., Au, C., Benedetto, A., Thompson, M. A., Clark, E., Gilliat, A. F., Young, A., Schmeisser, K. & Gems, D., 10/2017, In: Aging Cell. 16, 5, p. 1191-1194 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

LFASS: Label-Free Automated Survival Scoring for High-Throughput Nematode Assays

Benedetto, A., Bambade, T., Au, C., Tullet, J., Dang, H., Cetnar, K., Cabreiro, F. & Gems, D., 28/09/2017, In: Biorxiv. 23 p.

Research output: Contribution to Journal/Magazine › Journal article

Monsters in the uterus: a parthenogenetic quasi-program causes teratoma-like tumors during aging in wild-type C. elegans

Wang, H., Zhao, Y., Ezcurra, M., Gilliat, A. F., Hellberg, J., Benedetto, A., Athigapanich, T., Girstmair, J., Telford, M., Zhang, Z. & Gems, D., 10/08/2017, In: Biorxiv. 34 p.

Research output: Contribution to Journal/Magazine › Journal article

Involvement of heat shock proteins on Mn-induced toxicity in Caenorhabditis elegans

Avila, D. S., Benedetto, A., Au, C., Bornhorst, J. & Aschner, M., 2/11/2016, In: BMC Pharmacology and Toxicology. 17, 1, 9 p., 54.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

In vivo collective cell migration requires an LPAR2-dependent increase in tissue fluidity

Kuriyama, S., Theveneau, E., Benedetto, A., Parsons, M., Tanaka, M., Charras, G., Kabla, A. & Mayor, R., 7/07/2014, In: Journal of Cell Biology. 206, 1, p. 113-127 15 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Spatiotemporal control of gene expression using microfluidics

Benedetto, A., Accetta, G., Fujita, Y. & Charras, G., 7/04/2014, In: Lab on a Chip. 14, 7, p. 1336-1347 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans

Tullet, J. M. A., Araiz, C., Sanders, M. J., Au, C., Benedetto, A., Papatheodorou, I., Clark, E., Schmeisser, K., Jones, D., Schuster, E. F., Thornton, J. M. & Gems, D., 6/02/2014, In: PLoS Genetics. 10, 2, 16 p., e1004109.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Anthranilate fluorescence marks a calcium-propagated necrotic wave that promotes organismal death in C. elegans

Coburn, C., Allman, E., Mahanti, P., Benedetto, A., Cabreiro, F., Pincus, Z., Matthijssens, F., Araiz, C., Mandel, A., Vlachos, M., Edwards, S.-A., Fischer, G., Davidson, A., Pryor, R. E., Stevens, A., Slack, F. J., Tavernarakis, N., Braeckman, B. P., Schroeder, F. C. & Nehrke, K. & 1 others, Gems, D., 23/07/2013, In: Plos Biology. 11, 7, 17 p., e1001613.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Organotellurium and organoselenium compounds attenuate Mn-induced toxicity in Caenorhabditis elegans by preventing oxidative stress

Avila, D. S., Benedetto, A., Au, C., Manarin, F., Erikson, K., Soares, F. A., Rocha, J. B. T. & Aschner, M., 1/05/2012, In: Free Radical Biology and Medicine. 52, 9, p. 1903-1910 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Environmental exposure, obesity, and Parkinson's disease: lessons from fat and old worms

Aitlhadj, L., Avila, D. S., Benedetto, A., Aschner, M. & Stürzenbaum, S. R., 01/2011, In: Environmental Health Perspectives. 119, 1, p. 20-28 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Stressed-induced TMEM135 protein is part of a conserved genetic network involved in fat storage and longevity regulation in Caenorhabditis elegans

Exil, V. J., Silva Avila, D., Benedetto, A., Exil, E. A., Adams, M. R., Au, C. & Aschner, M., 3/12/2010, In: PLoS ONE. 5, 12, 11 p., e14228.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans

Benedetto, A., Au, C., Avila, D. S., Milatovic, D. & Aschner, M., 26/08/2010, In: PLoS Genetics. 6, 8

Research output: Contribution to Journal/Magazine › Journal article › peer-review

SMF-1, SMF-2 and SMF-3 DMT1 orthologues regulate and are regulated differentially by manganese levels in C. elegans

Au, C., Benedetto, A., Anderson, J., Labrousse, A., Erikson, K., Ewbank, J. J. & Aschner, M., 18/11/2009, In: PLoS ONE. 4, 11, 17 p., e7792.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Manganese-induced dopaminergic neurodegeneration: insights into mechanisms and genetics shared with Parkinson's disease

Benedetto, A., Au, C. & Aschner, M., 10/2009, In: Chemical Reviews. 109, 10, p. 4862-4884 23 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology

Leung, M. C. K., Williams, P. L., Benedetto, A., Au, C., Helmcke, K. J., Aschner, M. & Meyer, J. N., 11/2008, In: Toxicological sciences : an official journal of the Society of Toxicology. 106, 1, p. 5-28 24 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Antioxidant properties of blirubin in the model organism, Caenorhabditis elegans

McCaughan, D., Au, C., Benedetto, A., Milatovic, D., Aschner, J. & Aschner, M., 07/2008, In: International Journal of Neuroprotection and Neuroregeneration. 4, 3, p. 252-262 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Manganese transport in eukaryotes: the role of DMT1

Au, C., Benedetto, A. & Aschner, M., 07/2008, In: NeuroToxicology. 29, 4, p. 569-576 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genes required for osmoregulation and apical secretion in Caenorhabditis elegans

Liégeois, S., Benedetto, A., Michaux, G., Belliard, G. & Labouesse, M., 1/02/2007, In: Genetics. 175, 2, p. 709-724 16 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans

Liégeois, S., Benedetto, A., Garnier, J.-M., Schwab, Y. & Labouesse, M., 19/06/2006, In: Journal of Cell Biology. 173, 6, p. 949-961 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Overexpression of toll-like receptor 4 amplifies the host response to lipopolysaccharide and provides a survival advantage in transgenic mice

Bihl, F., Salez, L., Beaubier, M., Torres, D., Larivière, L., Laroche, L., Benedetto, A., Martel, D., Lapointe, J.-M., Ryffel, B. & Malo, D., 15/06/2003, In: Journal of Immunology. 170, 12, p. 6141-6150 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review