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Dr Helen Barnett

Lecturer in Statistics

  1. 2024
  2. Published

    A Seamless Phase I/II Platform Design with a Time-To-Event Efficacy Endpoint for Potential COVID-19 Therapies

    Jaki, T., Barnett, H., Titman, A. & Mozgunov, P., 30/11/2024, In: Statistical Methods in Medical Research. 33, 11-12, p. 2115-2130 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. E-pub ahead of print

    Joint TITE-CRM: A Design for Dose Finding Studies for Therapies with Late-Onset Safety and Activity Outcomes

    Barnett, H., Boix, O., Kontos, D. & Jaki, T., 17/04/2024, (E-pub ahead of print) In: Statistics in Biopharmaceutical Research. 29 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    A Comparison of Model-Free Phase I Dose Escalation Designs for Dual-Agent Combination Therapies

    Barnett, H., George, M., Skanji, D., Saint-Hilary, G., Jaki, T. & Mozgunov, P., 29/02/2024, In: Statistical Methods in Medical Research. 33, 2, p. 203-226 24 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. 2023
  6. Published

    Backfilling cohorts in phase I dose-escalation studies

    Barnett, H., Boix, O., Kontos, D. & Jaki, T., 30/06/2023, In: Clinical Trials. 20, 3, p. 261-268 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    A novel statistical test for treatment differences in clinical trials using a response‐adaptive forward‐looking Gittins Index Rule

    Barnett, H. Y., Villar, S. S., Geys, H. & Jaki, T., 31/03/2023, In: Biometrics. 79, 1, p. 86-97 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    An Updated Show of Hands

    Barnett, H., Karapiperi, A. & Kastis, E., 6/03/2023, In: MSOR Connections. 21, 1, p. 18-22 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. 2022
  10. Published

    Dose finding studies for therapies with late‐onset toxicities: A comparison study of designs

    Barnett, H., Boix, O., Kontos, D. & Jaki, T., 30/12/2022, In: Statistics in Medicine. 41, 30, p. 5767-5788 22 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. 2021
  12. Published

    Using an Interaction Parameter in Model-Based Phase I Trials for Combination Treatments? A Simulation Study

    Mozgunov, P., Knight, R., Barnett, H. & Jaki, T., 5/01/2021, In: International Journal of Environmental Research and Public Health. 18, 1, 19 p., 345.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Methods for Non-Compartmental Pharmacokinetic Analysis With Observations Below the Limit of Quantification

    Barnett, H. Y., Geys, H., Jacobs, T. & Jaki, T., 2/01/2021, In: Statistics in Biopharmaceutical Research. 13, 1, p. 59-70 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. 2018
  15. Published

    Optimal Designs for Non-Compartmental Analysis of Pharmacokinetic Studies

    Barnett, H. Y., Geys, H., Jacobs, T. & Jaki, T. F., 2018, In: Statistics in Biopharmaceutical Research. 10, 4, p. 255-263 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. 2017
  17. Published

    Comparing sampling methods for pharmacokinetic studies using model averaged derived parameters

    Barnett, H. Y., Geys, H., Jacobs, T. & Jaki, T., 30/11/2017, In: Statistics in Medicine. 36, 27, p. 4301-4315 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Optimizing pharmacokinetic studies utilizing microsampling

    Barnett, H. Y., 2017, Lancaster University. 186 p.

    Research output: ThesisDoctoral Thesis

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