Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes

Prescott, N. J., Lehne, B., Stone, K., Lee, J. C., Taylor, K., Knight, J., Papouli, E., Mirza, M. M., Simpson, M. A., Spain, S. L., Lu, G., Fraternali, F., Bumpstead, S. J., Gray, E., Amar, A., Bye, H., Green, P., Chung-Faye, G., Hayee, B. & Pollok, R. & 10 others, Satsangi, J., Parkes, M., Barrett, J. C., Mansfield, J. C., Sanderson, J., Lewis, C. M., Weale, M. E., Schlitt, T., Mathew, C. G. & UK IBD Genetics Consortium, 11/02/2015, In: PLoS Genetics. 11, 2, e1004955.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

CYP2A6 reduced activity gene variants confer reduction in lung cancer risk in African American smokers: findings from two independent populations

Wassenaar, C. A., Ye, Y., Cai, Q., Aldrich, M. C., Knight, J., Spitz, M. R., Wu, X., Blot, W. J. & Tyndale, R. F., 01/2015, In: Carcinogenesis. 36, 1, p. 99-103 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Investigation of TSPO variants in schizophrenia and antipsychotic treatment outcomes

Pouget, J. G., Gonçalves, V. F., Nurmi, E. L., Laughlin, C. P., Mallya, K. S., McCracken, J. T., Aman, M. G., McDougle, C. J., Scahill, L., Misener, V. L., Tiwari, A. K., Zai, C. C., Brandl, E. J., Felsky, D., Leung, A. Q., Lieberman, J. A., Meltzer, H. Y., Potkin, S. G., Niedling, C. & Steimer, W. & 4 others, Leucht, S., Knight, J., Müller, D. J. & Kennedy, J. L., 01/2015, In: Pharmacogenomics. 16, 1, p. 5-22 18 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Complex host genetics influence the microbiome in inflammatory bowel disease

Knights, D., Silverberg, M. S., Weersma, R. K., Gevers, D., Dijkstra, G., Huang, H., Tyler, A. D., van Sommeren, S., Imhann, F., Stempak, J. M., Huang, H., Vangay, P., Al-Ghalith, G. A., Russell, C., Sauk, J., Knight, J., Daly, M. J., Huttenhower, C. & Xavier, R. J., 2/12/2014, In: Genome Biology. 6, 12, 11 p., 107.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 6/11/2014, In: American Journal of Human Genetics. 95, 5, p. 535-552 18 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The role of leptin, melanocortin, and neurotrophin system genes on body weight in anorexia nervosa and bulimia nervosa

Yilmaz, Z., Kaplan, A. S., Tiwari, A. K., Levitan, R. D., Piran, S., Bergen, A. W., Kaye, W. H., Hakonarson, H., Wang, K., Berrettini, W. H., Brandt, H. A., Bulik, C. M., Crawford, S., Crow, S., Fichter, M. M., Halmi, K. A., Johnson, C. L., Keel, P. K., Klump, K. L. & Magistretti, P. & 7 others, Mitchell, J., Strober, M., Thornton, L. M., Treasure, J., Woodside, D. B., Knight, J. & Kennedy, J. L., 08/2014, In: Journal of Psychiatric Research. 55, p. 77-86 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Biological insights from 108 schizophrenia-associated genetic loci

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 24/07/2014, In: Nature. 511, 7510, p. 421-427 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Protein kinase cAMP-dependent regulatory type II beta (PRKAR2B) gene variants in antipsychotic-induced weight gain

Gagliano, S. A., Tiwari, A. K., Freeman, N., Lieberman, J. A., Meltzer, H. Y., Kennedy, J. L., Knight, J. & Müller, D. J., 07/2014, In: Human Psychopharmacology: Clinical and Experimental. 29, 4, p. 330-335 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris

Navarini, A. A., Simpson, M. A., Weale, M., Knight, J., Carlavan, I., Reiniche, P., Burden, D. A., Layton, A., Bataille, V., Allen, M., Pleass, R., Pink, A., Creamer, D., English, J., Munn, S., Walton, S., Willis, C., Déret, S., Voegel, J. J. & Spector, T. & 4 others, Smith, C. H., Trembath, R. C., Barker, J. N. W. N. & Acne Genetic Study Group, 13/06/2014, In: Nature Communications. 5, 6 p., 4020.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization

Gagliano, S. A., Barnes, M. R., Weale, M. E. & Knight, J., 20/05/2014, In: PLoS ONE. 9, 5, 14 p., e98122.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1

Xu, W., Cohen-Woods, S., Chen, Q., Noor, A., Knight, J., Hosang, G., Parikh, S. V., De Luca, V., Tozzi, F., Muglia, P., Forte, J., McQuillin, A., Hu, P., Gurling, H. M. D., Kennedy, J. L., McGuffin, P., Farmer, A., Strauss, J. & Vincent, J. B., 4/01/2014, In: Journal of Medical Genetics. 15, 13 p., 2.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis

Knight, J., Spain, S. L., Capon, F., Hayday, A., Nestle, F. O., Clop, A., Barker, J. N. W. N., Weale, M. E., Trembath, R. C. & Wellcome Trust Case Control Consortium, 1/12/2012, In: Human Molecular Genetics. 21, 23, p. 5185-5192 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Tsoi, L. C., Spain, S. L., Knight, J., Ellinghaus, E., Stuart, P. E., Capon, F., Ding, J., Li, Y., Tejasvi, T., Gudjonsson, J. E., Kang, H. M., Allen, M. H., McManus, R., Novelli, G., Samuelsson, L., Schalkwijk, J., Ståhle, M., Burden, A. D., Smith, C. H. & Cork, M. J. & 31 others, Estivill, X., Bowcock, A. M., Krueger, G. G., Weger, W., Worthington, J., Tazi-Ahnini, R., Nestle, F. O., Hayday, A., Hoffmann, P., Winkelmann, J., Wijmenga, C., Langford, C., Edkins, S., Andrews, R., Blackburn, H., Strange, A., Band, G., Pearson, R. D., Vukcevic, D., Spencer, C. C. A., Deloukas, P., Mrowietz, U., Schreiber, S., Weidinger, S., Koks, S., Kingo, K., Esko, T., Metspalu, A., Lim, H. W., Voorhees, J. J. & Collaborative Association Study of Psoriasis (CASP), 12/2012, In: Nature Genetics. 44, 12, p. 1341-1348 8 p.

Research output: Contribution to Journal/Magazine › Letter › peer-review

Introduction to genetic association studies

Lewis, C. M. & Knight, J., 03/2012, In: Cold Spring Harbor Protocols. 2012, 3, p. 297-306 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis

Onoufriadis, A., Simpson, M. A., Pink, A. E., Di Meglio, P., Smith, C. H., Pullabhatla, V., Knight, J., Spain, S. L., Nestle, F. O., Burden, A. D., Capon, F., Trembath, R. C. & Barker, J. N. W. N., 9/09/2011, In: American Journal of Human Genetics. 89, 3, p. 432-437 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A genome-wide significant linkage for severe depression on chromosome 3: the depression network study

Breen, G., Webb, B. T., Butler, A. W., van den Oord, E. J. C. G., Tozzi, F., Craddock, N., Gill, M., Korszun, A., Maier, W., Middleton, L., Mors, O., Owen, M. J., Cohen-Woods, S., Perry, J., Galwey, N. W., Upmanyu, R., Craig, I., Lewis, C. M., Ng, M. & Brewster, S. & 8 others, Preisig, M., Rietschel, M., Jones, L., Knight, J., Rice, J., Muglia, P., Farmer, A. E. & McGuffin, P., 08/2011, In: American Journal of Psychiatry. 168, 8, p. 840-847 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Using functional annotation for the empirical determination of Bayes Factors for genome-wide association study analysis

Knight, J., Barnes, M. R., Breen, G. & Weale, M. E., 27/04/2011, In: PLoS ONE. 6, 4, 8 p., e14808.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Common variants in DGKK are strongly associated with risk of hypospadias

van der Zanden, L. F. M., van Rooij, I. A. L. M., Feitz, W. F. J., Knight, J., Donders, A. R. T., Renkema, K. Y., Bongers, E. M. H. F., Vermeulen, S. H. H. M., Kiemeney, L. A. L. M., Veltman, J. A., Arias-Vásquez, A., Zhang, X., Markljung, E., Qiao, L., Baskin, L. S., Nordenskjöld, A., Roeleveld, N., Franke, B. & Knoers, N. V. A. M., 01/2011, In: Nature Genetics. 43, 1, p. 48-50 3 p.

Research output: Contribution to Journal/Magazine › Letter › peer-review

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

Strange, A., Capon, F., Spencer, C. C. A., Knight, J., Weale, M. E., Allen, M. H., Barton, A., Band, G., Bellenguez, C., Bergboer, J. G. M., Blackwell, J. M., Bramon, E., Bumpstead, S. J., Casas, J. P., Cork, M. J., Corvin, A., Deloukas, P., Dilthey, A., Duncanson, A. & Edkins, S. & 31 others, Estivill, X., Fitzgerald, O., Freeman, C., Giardina, E., Gray, E., Hofer, A., Hüffmeier, U., Hunt, S. E., Irvine, A. D., Jankowski, J., Kirby, B., Langford, C., Lascorz, J., Leman, J., Leslie, S., Mallbris, L., Markus, H. S., Mathew, C. G., McLean, W. H. I., McManus, R., Mössner, R., Moutsianas, L., Naluai, A. T., Nestle, F. O., Novelli, G., Onoufriadis, A., Palmer, C. N. A., Perricone, C., Pirinen, M., Plomin, R. & Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium 2, 11/2010, In: Nature Genetics. 42, 11, p. 985-990 6 p.

Research output: Contribution to Journal/Magazine › Letter › peer-review

An investigation of candidate regions for association with bipolar disorder

Knight, J., Rochberg, N. S., Saccone, S. F., Nurnberger, J. I., Rice, J. P. & NIMH Genetics Initiative Bipolar Disorder Consortium, 5/10/2010, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 153B, 7, p. 1292-1297 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The Bipolar Association Case-Control Study (BACCS) and meta-analysis: no association with the 5,10-Methylenetetrahydrofolate reductase gene and bipolar disorder

Cohen-Woods, S., Craig, I., Gaysina, D., Gray, J., Gunasinghe, C., Craddock, N., Elkin, A., Jones, L., Kennedy, J., King, N., Korszun, A., Knight, J., Owen, M., Parikh, S., Strauss, J., Sterne, A., Tozzi, F., Perry, J., Muglia, P. & Vincent, J. & 2 others, McGuffin, P. & Farmer, A., 5/10/2010, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 153B, 7, p. 1298-1304 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders

Beall, C. M., Cavalleri, G. L., Deng, L., Elston, R. C., Gao, Y., Knight, J., Li, C., Li, J. C., Liang, Y., McCormack, M., Montgomery, H. E., Pan, H., Robbins, P. A., Shianna, K. V., Tam, S. C., Tsering, N., Veeramah, K. R., Wang, W., Wangdui, P. & Weale, M. E. & 9 others, Xu, Y., Xu, Z., Yang, L., Zaman, M. J., Zeng, C., Zhang, L., Zhang, X., Zhaxi, P. & Zheng, Y. T., 22/06/2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 25, p. 11459-11464 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Software for generating liability distributions for pedigrees conditional on their observed disease states and covariates

Campbell, D. D., Sham, P. C., Knight, J., Wickham, H. & Landau, S., 02/2010, In: Genetic Epidemiology. 34, 2, p. 159-170 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Depression Case Control (DeCC) study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder

Cohen-Woods, S., Gaysina, D., Craddock, N., Farmer, A., Gray, J., Gunasinghe, C., Hoda, F., Jones, L., Knight, J., Korszun, A., Owen, M. J., Sterne, A., Craig, I. W. & McGuffin, P., 15/04/2009, In: Human Molecular Genetics. 18, 8, p. 1504-1509 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A comparison of association statistics between pooled and individual genotypes

Knight, J., Saccone, S. F., Zhang, Z., Ballinger, D. G. & Rice, J. P., 03/2009, In: Human Heredity. 67, 4, p. 219-225 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration

Simpson, C. L., Lemmens, R., Miskiewicz, K., Broom, W. J., Hansen, V. K., van Vught, P. W. J., Landers, J. E., Sapp, P., Van Den Bosch, L., Knight, J., Neale, B. M., Turner, M. R., Veldink, J. H., Ophoff, R. A., Tripathi, V. B., Beleza, A., Shah, M. N., Proitsi, P., Van Hoecke, A. & Carmeliet, P. & 10 others, Horvitz, H. R., Leigh, P. N., Shaw, C. E., van den Berg, L. H., Sham, P. C., Powell, J. F., Verstreken, P., Brown, R. H., Robberecht, W. & Al-Chalabi, A., 1/02/2009, In: Human Molecular Genetics. 18, 3, p. 472-481 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

DSM-IV combined type ADHD shows familial association with sibling trait scores: a sampling strategy for QTL linkage

Chen, W., Zhou, K., Sham, P., Franke, B., Kuntsi, J., Campbell, D., Fleischman, K., Knight, J., Andreou, P., Arnold, R., Altink, M., Boer, F., Boholst, M. J., Buschgens, C., Butler, L., Christiansen, H., Fliers, E., Howe-Forbes, R., Gabriëls, I. & Heise, A. & 30 others, Korn-Lubetzki, I., Marco, R., Medad, S., Minderaa, R., Müller, U. C., Mulligan, A., Psychogiou, L., Rommelse, N., Sethna, V., Uebel, H., McGuffin, P., Plomin, R., Banaschewski, T., Buitelaar, J., Ebstein, R., Eisenberg, J., Gill, M., Manor, I., Miranda, A., Mulas, F., Oades, R. D., Roeyers, H., Rothenberger, A., Sergeant, J., Sonuga-Barke, E., Steinhausen, H.-C., Taylor, E., Thompson, M., Faraone, S. V. & Asherson, P., 5/12/2008, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 147B, 8, p. 1450-1460 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A simple method for assessing the strength of evidence for association at the level of the whole gene

Curtis, D., Vine, A. E. & Knight, J., 17/11/2008, In: Advances and Applications in Bioinformatics and Chemistry : AABC. 1, p. 115-120 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

CLUMPHAP: a simple tool for performing haplotype-based association analysis

Knight, J., Curtis, D. & Sham, P. C., 09/2008, In: Genetic Epidemiology. 32, 6, p. 539-545 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Investigation into the ability of SNP chipsets and microsatellites to detect association with a disease locus

Curtis, D., Vine, A. E. & Knight, J., 07/2008, In: Annals of Human Genetics. 72, 4, p. 547-556 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Differential methylation of the X-chromosome is a possible source of discordance for bipolar disorder female monozygotic twins

Rosa, A., Picchioni, M. M., Kalidindi, S., Loat, C. S., Knight, J., Toulopoulou, T., Vonk, R., van der Schot, A. C., Nolen, W., Kahn, R. S., McGuffin, P., Murray, R. M. & Craig, I. W., 5/06/2008, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 147B, 4, p. 459-462 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Study of regions of extended homozygosity provides a powerful method to explore haplotype structure of human populations

Curtis, D., Vine, A. E. & Knight, J., 03/2008, In: Annals of Human Genetics. 72, 2, p. 261-278 18 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Association of the serotonin transporter gene, neuroticism and smoking behaviours

O'Gara, C., Knight, J., Stapleton, J., Luty, J., Neale, B., Nash, M., Heuzo-Diaz, P., Hoda, F., Cohen, S., Sutherland, G., Collier, D., Sham, P., Ball, D., McGuffin, P. & Craig, I., 2008, In: Journal of Human Genetics . 53, 3, p. 239-246 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Dopamine genes and pathological gambling in discordant sib-pairs

da Silva Lobo, D. S., Vallada, H. P., Knight, J., Martins, S. S., Tavares, H., Gentil, V. & Kennedy, J. L., 12/2007, In: Journal of Gambling Studies. 23, 4, p. 421-433 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Application of multi-locus analytical methods to identify interacting loci in case-control studies

Vermeulen, S. H. H. M., Den Heijer, M., Sham, P. C. & Knight, J., 09/2007, In: Annals of Human Genetics. 71, 5, p. 689-700 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Age at onset in sod1-mediated amyotrophic lateral sclerosis shows familiality

Fogh, I., Rijsdijk, F., Andersen, P. M., Sham, P. C., Knight, J., Neale, B., McKenna-Yasek, D., Silani, V., Brown, R. H., Powell, J. F. & Al-Chalabi, A., 08/2007, In: Neurogenetics. 8, 3, p. 235-236 2 p.

Research output: Contribution to Journal/Magazine › Letter › peer-review

A pragmatic suggestion for dealing with results for candidate genes obtained from genome wide association studies

Curtis, D., Vine, A. E. & Knight, J., 10/05/2007, In: Genetics. 8, 6 p., 20.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Homing in on depression genes

McGuffin, P., Cohen, S. & Knight, J., 02/2007, In: American Journal of Psychiatry. 164, 2, p. 195-197 3 p.

Research output: Contribution to Journal/Magazine › Editorial › peer-review

Investigation of the ability of haplotype association and logistic regression to identify associated susceptibility loci

North, B. V., Sham, P. C., Knight, J., Martin, E. R. & Curtis, D., 11/2006, In: Annals of Human Genetics. 70, 6, p. 893-906 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes

Brookes, K., Xu, X., Chen, W., Zhou, K., Neale, B., Lowe, N., Anney, R., Franke, B., Gill, M., Ebstein, R., Buitelaar, J., Sham, P., Campbell, D., Knight, J., Andreou, P., Altink, M., Arnold, R., Boer, F., Buschgens, C. & Butler, L. & 42 others, Christiansen, H., Feldman, L., Fleischman, K., Fliers, E., Howe-Forbes, R., Goldfarb, A., Heise, A., Gabriëls, I., Korn-Lubetzki, I., Johansson, L., Marco, R., Medad, S., Minderaa, R., Mulas, F., Müller, U., Mulligan, A., Rabin, K., Rommelse, N., Sethna, V., Sorohan, J., Uebel, H., Psychogiou, L., Weeks, A., Barrett, R., Craig, I., Banaschewski, T., Sonuga-Barke, E., Eisenberg, J., Kuntsi, J., Manor, I., McGuffin, P., Miranda, A., Oades, R. D., Plomin, R., Roeyers, H., Rothenberger, A., Sergeant, J., Steinhausen, H.-C., Taylor, E., Thompson, M., Faraone, S. V. & Asherson, P., 10/2006, In: Molecular Psychiatry. 11, 10, p. 934-953 20 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Design and analysis of association studies using pooled DNA from large twin samples

Knight, J. & Sham, P., 09/2006, In: Behavior Genetics. 36, 5, p. 665-677 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

NADPH oxidase (CYBA) and FcgammaR polymorphisms as risk factors for aggressive periodontitis: a case-control association study

Nibali, L., Parkar, M., Brett, P., Knight, J., Tonetti, M. S. & Griffiths, G. S., 08/2006, In: Journal of Clinical Periodontology. 33, 8, p. 529-539 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease

Hamilton, G., Samedi, F., Knight, J., Archer, N., Foy, C., Walter, S., Turic, D., Jehu, L., Moore, P., Hollingworth, P., O'Donovan, M. C., Williams, J., Owen, M. J., Lovestone, S. & Powell, J. F., 19/06/2006, In: Neuroscience Letters. 401, 1-2, p. 77-80 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Program report: GENECOUNTING support programs

Curtis, D., Knight, J. & Sham, P. C., 03/2006, In: Annals of Human Genetics. 70, Pt 2, p. 277-279 3 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A common haplotype of the dopamine transporter gene associated with attention-deficit/hyperactivity disorder and interacting with maternal use of alcohol during pregnancy

Brookes, K.-J., Mill, J., Guindalini, C., Curran, S., Xu, X., Knight, J., Chen, C.-K., Huang, Y.-S., Sethna, V., Taylor, E., Chen, W., Breen, G. & Asherson, P., 01/2006, In: Archives of General Psychiatry. 63, 1, p. 74-81 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Whole genome linkage scan of recurrent depressive disorder from the depression network study

McGuffin, P., Knight, J., Breen, G., Brewster, S., Boyd, P. R., Craddock, N., Gill, M., Korszun, A., Maier, W., Middleton, L., Mors, O., Owen, M. J., Perry, J., Preisig, M., Reich, T., Rice, J., Rietschel, M., Jones, L., Sham, P. & Farmer, A. E., 15/11/2005, In: Human Molecular Genetics. 14, 22, p. 3337-3345 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

DNA pooling analysis of ADHD and genes regulating vesicle release of neurotransmitters

Brookes, K. J., Knight, J., Xu, X. & Asherson, P., 5/11/2005, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 139B, 1, p. 33-37 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A new method of linkage analysis using LOD scores for quantitative traits supports linkage of monoamine oxidase activity to D17S250 in the Collaborative Study on the Genetics of Alcoholism pedigrees

Curtis, D., Knight, J. & Sham, P. C., 09/2005, In: Psychiatric Genetics. 15, 3, p. 181-187 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

SNPs, microarrays and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children

Butcher, L. M., Meaburn, E., Knight, J., Sham, P. C., Schalkwyk, L. C., Craig, I. W. & Plomin, R., 15/05/2005, In: Human Molecular Genetics. 14, 10, p. 1315-1325 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

DNA pooling analysis of 21 norepinephrine transporter gene SNPs with attention deficit hyperactivity disorder: no evidence for association

Xu, X., Knight, J., Brookes, K., Mill, J., Sham, P., Craig, I., Taylor, E. & Asherson, P., 5/04/2005, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 134B, 1, p. 115-118 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Quantitative trait locus analysis of candidate gene alleles associated with attention deficit hyperactivity disorder (ADHD) in five genes: DRD4, DAT1, DRD5, SNAP-25, and 5HT1B

Mill, J., Xu, X., Ronald, A., Curran, S., Price, T., Knight, J., Craig, I., Sham, P., Plomin, R. & Asherson, P., 5/02/2005, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 133B, 1, p. 68-73 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease

Garcia-Barcelo, M., Ganster, R. W., Lui, V. C. H., Leon, T. Y. Y., So, M.-T., Lau, A. M. F., Fu, M., Sham, M.-H., Knight, J., Zannini, M. S., Sham, P. C. & Tam, P. K. H., 15/01/2005, In: Human Molecular Genetics. 14, 2, p. 191-204 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The effect of haplotype-block definitions on inference of haplotype-block structure and htSNPs selection

Ding, K., Zhou, K., Zhang, J., Knight, J., Zhang, X. & Shen, Y., 01/2005, In: Molecular Biology and Evolution. 22, 1, p. 148-159 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A central resource for accurate allele frequency estimation from pooled DNA genotyped on DNA microarrays

Simpson, C. L., Knight, J., Butcher, L. M., Hansen, V. K., Meaburn, E., Schalkwyk, L. C., Craig, I. W., Powell, J. F., Sham, P. C. & Al-Chalabi, A., 2005, In: Nucleic Acids Research. 33, 3, e25.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Haplotype analysis of SNAP-25 suggests a role in the aetiology of ADHD

Mill, J., Richards, S., Knight, J., Curran, S., Taylor, E. & Asherson, P., 08/2004, In: Molecular Psychiatry. 9, 8, p. 801-810 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Attention-Deficit Hyperactivity Disorder in the post-genomic era

Asherson, P., Knight, J. & IMAGE Consortium, 07/2004, In: European Child and Adolescent Psychiatry. 13 , Suppl 1, p. I50-70 21 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene

Flomen, R., Knight, J., Sham, P., Kerwin, R. & Makoff, A., 1/04/2004, In: Nucleic Acids Research. 32, 7, p. 2113-2122 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A survey of current software for genetic power calculations

Knight, J., 2/03/2004, In: BMC Genomics. 1, 3, p. 225-227 3 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Endothelial nitric oxide gene haplotypes and risk of cerebral small-vessel disease

Hassan, A. E. M., Gormley, K., O'Sullivan, M., Knight, J., Sham, P. C., Vallance, P., Bamford, J. & Markus, H. S., 03/2004, In: Stroke; a journal of cerebral circulation. 35, 3, p. 654-659 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Haplotype association analysis of discrete and continuous traits using mixture of regression models

Sham, P. C., Rijsdijk, F. V., Knight, J., Makoff, A., North, B. & Curtis, D., 03/2004, In: Behavior Genetics. 34, 2, p. 207-214 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Mapping loci influencing blood pressure in the Framingham pedigrees using model-free LOD score analysis of a quantitative trait

Knight, J., North, B. V., Sham, P. C. & Curtis, D., 31/12/2003, In: Genetics. 4 , Suppl. 1, 4 p., S74.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genome-wide mapping of human loci for essential hypertension

Caulfield, M., Munroe, P., Pembroke, J., Samani, N., Dominiczak, A., Brown, M., Benjamin, N., Webster, J., Ratcliffe, P., O'Shea, S., Papp, J., Taylor, E., Dobson, R., Knight, J., Newhouse, S., Hooper, J., Lee, W., Brain, N., Clayton, D. & Lathrop, G. M. & 3 others, Farrall, M., Connell, J. & MRC British Genetics of Hypertension Study, 21/06/2003, In: The Lancet. 361, 9375, p. 2118-2123 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Human chromosome 17 in essential hypertension

Knight, J., Munroe, P. B., Pembroke, J. C. & Caulfield, M. J., 03/2003, In: Annals of Human Genetics. 67, 2, p. 193-206 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Haplotype and linkage disequilibrium analysis to characterise a region in the calcium channel gene CACNA1A associated with idiopathic generalised epilepsy

Chioza, B., Osei-Lah, A., Nashef, L., Suarez-Merino, B., Wilkie, H., Sham, P., Knight, J., Asherson, P. & Makoff, A. J., 12/2002, In: European Journal of Human Genetics. 10, 12, p. 857-864 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Investigation of chromosome 17q as a locus for human essential hypertension in African Caribbeans

Knight, J., Gardner, G. T., Clark, A. J. & Caulfield, M. J., 06/2000, In: Journal of Human Hypertension. 14, 6, p. 385-387 3 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

1990-2000: progress in determining high blood pressure genes

Munroe, P. B., Knight, J. & Caulfield, M. J., 05/2000, In: Annals of the Academy of Medicine, Singapore. 29, 3, p. 357-363 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review