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Biomedical and Life Sciences

  1. 2022
  2. Published

    Extracellular release of two peptidases dominates generation of the trypanosome quorum-sensing signal

    Tettey, M. D., Rojas, F. & Matthews, K. R., 9/06/2022, In: Nature Communications. 13, 1, 14 p., 3322.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Mistargeting of aggregation prone mitochondrial proteins activates a nucleus-mediated posttranscriptional quality control pathway in trypanosomes

    Dewar, C. E., Oeljeklaus, S., Mani, J., Muehlhaeuser, W. W. D., von Kaenel, C., Zimmermann, J., Ochsenreiter, T., Warscheid, B. & Schneider, A., 2/06/2022, In: Nature Communications. 13, 3084.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    Development of CRISPR/Cas9-based Novel Vaccines against Poultry Viruses

    Vilela, J. & Munir, M., 27/05/2022, In: Access Microbiology. 4, 5

    Research output: Contribution to Journal/MagazineMeeting abstractpeer-review

  5. Published

    Nanoformulated Bumetanide Ameliorates Social Deficiency in BTBR Mice Model of Autism Spectrum Disorder

    Lv, H., Gu, X., Shan, X., Zhu, T., Ma, B., Zhang, H.-T., Bambini-Junior, V., Zhang, T., Li, W.-G., Gao, X. & Li, F., 23/05/2022, In: Frontiers in Immunology. 13, 13 p., 870577.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Effect of Escitalopram on the Number of DCX-Positive Cells and NMUR2 Receptor Expression in the Rat Hippocampus under the Condition of NPSR Receptor Blockade

    Piwowarczyk-Nowak, A., Pałasz, A., Suszka-Świtek, A., Błaszczyk, I., Bogus, K., Łasut-Szyszka, B., Krzystanek, M. & Worthington, J. J., 20/05/2022, In: Pharmaceuticals. 15, 5, 14 p., 631.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Selective Wee1 degradation by PROTAC degraders recruiting VHL and CRBN E3 ubiquitin ligases

    Aublette, M. C., Harrison, T. A., Thorpe, E. J. & Gadd, M. S., 15/05/2022, In: Bioorganic & medicinal chemistry letters. 64, 8 p., 128636.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions

    Zárate-Potes, A., Ali, I., Ribeiro Camacho, M., Brownless, H. & Benedetto, A., 10/05/2022, In: Frontiers in Microbiology. 13, 17 p., 853629.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Editorial: The Neurovascular Unit as a Potential Biomarker and Therapeutic Target in Cerebrovascular Disease

    Nizari, S., Hawkes, C. A., Hattori, Y. & Mishra, A., 5/05/2022, In: Frontiers in Aging Neuroscience. 14, 2 p., 908716.

    Research output: Contribution to Journal/MagazineEditorialpeer-review

  10. Published

    The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei

    Iyer, A., Niemann, M., Serricchio, M., Dewar, C. E., Oeljeklaus, S., Farine, L., Warscheid, B., Schneider, A. & Bütikofer, P., 2/05/2022, In: PLoS Pathogens. 18, 5, e1009717.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Altered medial prefrontal cortex and dorsal raphé activity predict genotype and correlate with abnormal learning behaviour in a mouse model of autism-associated 2p16.3 deletion

    Hughes, R., Whittingham-Dowd, J., Clapcote, S., Broughton, S. & Dawson, N., 30/04/2022, In: Autism Research. 15, 4, p. 614-627 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    Characterization of a highly diverged mitochondrial ATP synthase Fo subunit in Trypanosoma brucei

    Dewar, C. E., Oeljeklaus, S., Wenger, C., Warscheid, B. & Schneider, A., 30/04/2022, In: Journal of Biological Chemistry. 298, 4, 101829.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    High-Throughput Screening of Microbial Isolates with Impact on Caenorhabditis elegans Health

    Ali, I., Martin, J., Zárate-Potes, A. & Benedetto, A., 28/04/2022, In: Journal of Visualized Experiments. 2022, 182, e63860.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Forthcoming

    Cannabidiol (CBD) may influence substrate utilisation during and muscle recovery following damaging exercise

    Gaffney, C., Cunnington, J., Greathead, N., Rigby, E., Scott, D., Montemayor, M., Garvey, H. & Wright, K., 24/04/2022, (Accepted/In press).

    Research output: Contribution to conference - Without ISBN/ISSN Abstractpeer-review

  15. Published

    CO2 signaling mediates neurovascular coupling in the cerebral cortex

    Hosford, P., Wells, J., Nizari, S., Christie, I., Theparambil, S., Castro, P., Hadjihambi, A., Barros, L., Ruminot, I., Lythgoe, M. & Gourine, A., 19/04/2022, In: Nature Communications. 13, 2125.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Assessing the inflammatory response to in vitro polymicrobial wound biofilms in a skin epidermis model

    Brown, J. L., Townsend, E., Short, R. D., Williams, C., Woodall, C., Nile, C. J. & Ramage, G., 7/04/2022, In: npj Biofilms and Microbiomes. 8, 1, p. 1-12 19 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    BACE1 Overexpression Reduces SH-SY5Y Cell Viability Through a Mechanism Distinct from Amyloid-β Peptide Accumulation: Beta Prime-Mediated Competitive Depletion of sAβPPα

    Owens, L., Bracewell, J., Benedetto, A., Dawson, N., Gaffney, C. & Parkin, E., 5/04/2022, In: Journal of Alzheimer's Disease. 86, 3, p. 1201-1220 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Temperature, humidity and outdoor air quality indicators influence COVID-19 spread rate and mortality in major cities of Saudi Arabia

    Ismail, I. M. I., Rashid, M. I., Ali, N., Altaf, B. A. S. & Munir, M., 31/03/2022, In: Environmental Research. 204, Part B, 10 p., 112071.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    Twelve lateral flow immunoassays (LFAs) to detect SARS-CoV-2 antibodies

    Owen, S. I., Williams, C. T., Garrod, G., Fraser, A. J., Menzies, S., Baldwin, L., Brown, L., Byrne, R. L., Collins, A. M., Cubas-Atienzar, A. I., de Vos, M., Edwards, T., Escadafal, C., Ferreira, D. M., Fletcher, T., Hyder-Wright, A., Kay, G. A., Kontogianni, K., Mason, J. & Mitsi, E. & 7 others, Planche, T., Sacks, J. A., Taylor, J., Todd, S., Tully, C., Cuevas, L. E. & Adams, E. R., 31/03/2022, In: Journal of Infection. 84, 3, p. 355-360 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    VP2 virus-like particles elicit protective immunity against duckling short beak and dwarfism syndrome in ducks

    Xiao, S., Wang, S., Jiang, D., Cheng, X., Zhu, X., Lin, F., Yu, B., Dong, H., Wang, X., Munir, M., Rohaim, M. A., Chen, S. & Chen, S., 31/03/2022, In: Transboundary and Emerging Diseases. 69, 2, p. 570-578 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    The Amyloid Precursor Protein Plays Differential Roles in the UVA Resistance and Proliferation of Human Retinal Pigment Epithelial Cells

    Sultan, F. & Parkin, E., 30/03/2022, In: Protein and Peptide Letters. 29, 4, p. 313-327 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    SARS-CoV-2 Interacts with Mucosal Dysbiosis to Cause the Wide Range of Disease Seen in Covid-19

    Morris, J., Shepherd, R., Wray, M., Diep, P.-T. & Rigby, R., 26/03/2022, In: Austin Journal of Pulmonary and Respiratory Medicine. 9, 1, 7 p., 1086.

    Research output: Contribution to Journal/MagazineReview articlepeer-review

  23. Published

    In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus

    Menzies, S. K., Clare, R. H., Xie, C., Westhorpe, A., Hall, S. R., Edge, R. J., Alsolaiss, J., Crittenden, E., Marriott, A. E., Harrison, R. A., Kool, J. & Casewell, N. R., 18/03/2022, In: Toxicon: X. 14, p. 100118

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    The Polymerization of Homogentisic Acid In Vitro as a Model for Pyomelanin Formation

    Galeb, H., Lamantia, A., Robson, A., König, K., Eichhorn, J., Baldock, S., Ashton, M., Baum, J., Mort, R., Robinson, B., Schacher, F., Chechik, V., Taylor, A. & Hardy, J., 17/03/2022, In: Macromolecular Chemistry and Physics. 223, 6, 10 p., 2100489.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    The impact of obesity and bariatric surgery on the immune microenvironment of the endometrium

    Naqvi, A., MacKintosh, M. L., Derbyshire, A. E., Tsakiroglou, A.-M., Walker, T. D. J., McVey, R. J., Bolton, J., Fergie, M., Bagley, S., Ashton, G., Pemberton, P. W., Syed, A. A., Ammori, B. J., Byers, R. & Crosbie, E. J., 1/03/2022, In: International Journal of Obesity. 46, p. 605-612

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  26. Published

    Antipsychotics increase steroidogenic enzyme gene expression in the rat brainstem

    Bogus, K., Żarczyńska, M., Pałasz, A., Suszka-Świtek, A., Worthington, J. J., Krzystanek, M. & Żarczyński, P., 28/02/2022, In: Molecular Biology Reports. 49, 2, p. 1601-1608 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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