Pick's disease is associated with mutations in the tau gene.

Pickering-Brown, S., Baker, M., Yen, S-H., Liu, W-K., Hasegawa, M., Cairns, N., Lantos, P. L., Rossor, M., Iwatsubo, T., Davies, Y., Allsop, D., Furlong, R., Owen, F., Hardy, J., David Mann, D. & Hutton, M., 12/2000, In: Annals of Neurology. 48, 6, p. 589-867 279 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Characterisation of peptidyl boronic acid inhibitors of mammalian 20S and 26S proteasomes and their inhibition of proteasomes in cultured cells

Gardner, R. C., Assinder, S. J., Christie, G., Mason, G. G. F., Markwell, R., Wadsworth, H., McLaughlin, M., King, R., Chabot-Fletcher, M. C., Breton, J., Allsop, D. & Rivett, A. J., 2000, In: Biochemical Journal. 346, p. 447-454 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran.

Twyman, L. J. & Allsop, D., 12/1999, In: Tetrahedron Letters. 40, 52, p. 9383-9384 2 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Alzheimer's Disease: correlation of the suppression of β-Amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome

Christie, G., Markwell, R. E., Gray, C. W., Smith, L., Godfrey, F., Mansfield, F., Wadsworth, H., King, R., McLaughlin, M., Cooper, D. G., Ward, R. V., Howlett, D. R., Hartmann, T., Lichtenthaler, S. F., Beyreuther, K., Underwood, J., Gribble, S. K., Cappai, R., Masters, C. L., Tamaoka, A., & 4 othersGardner, R. L., Rivett, A. J., Karran, E. H. & Allsop, D., 07/1999, In: Journal of Neurochemistry. 73, 1, p. 195-204 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Biological activity associated with a high molecular weight form of β-amyloid.

Howlett, D. R., Ward, R. V., Bresciani, L., Jennings, K. H., Christie, G., Allsop, D., Gray, C. W. & Karran, E. H., 1999, In: Alzheimer's Reports. 2, p. 171-177 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Presenilins: in search of functionality

Karran, E. H., Allsop, D., Christie, G., Davis, J., Gray, C., Mansfield, F. & Ward, R. V., 08/1998, In: Biochemical Society Transactions. 26, 3, p. 491-496 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Fibrillogenesis of β-amyloid

Allsop, D., Howlett, D., Christie, G. & Karran, E., 08/1998, In: Biochemical Society Transactions. 26, 3, p. 459-463 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides

Hartmann, T., Bieger, S. C., Brühl, B., Tienari, P. J., Ida, N., Allsop, D., Roberts, G. W., Masters, C. L., Dotti, C. G., Unsicker, K. & Beyreuther, K., 09/1997, In: Nature Medicine. 3, 9, p. 1016-1020 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Effect of aluminium on expression and processing of amyloid precursor protein

Neill, D., Leake, A., Hughes, D., Keith, A. B., Taylor, G. A., Allsop, D., Rima, B. K., Morris, C., Candy, J. M. & Edwardson, J. A., 15/11/1996, In: Journal of Neuroscience Research. 46, 4, p. 395-403 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Aggregation and metal-binding properties of mutant forms of the amyloid Aβ peptide of Alzheimer's disease

Clements, A., Allsop, D., Walsh, D. M. & Williams, C. H., 02/1996, In: Journal of Neurochemistry. 66, 2, p. 740-747 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The immunoreactive profile at the N-terminal region of Aβ1-39/40 but not Aβ1-42 changes with transition from monomer/dimer to further peptide aggregates

Kametani, F., Tanaka, K., Tokuda, T. & Allsop, D., 12/12/1995, In: Brain Research. 703, 1-2, p. 237-241 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Inflammatory mechanisms in Alzheimer's disease

Eikelenboom, P., Zhan, S. S., van Gool, W. A. & Allsop, D., 12/1994, In: Trends in Pharmacological Sciences. 15, 12, p. 447-450 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Gerstmann-Sträussler-Scheinker disease showing β-protein type cerebellar and cerebral amyloid angiopathy

Ikeda, S. I., Yanagisawa, N., Allsop, D. & Glenner, G. G., 09/1994, In: Acta Neuropathologica. 88, 3, p. 262-266 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Human IMR-32 neuroblastoma cells as a model cell line in Alzheimer's disease research

Neill, D., Hughes, D., Edwardson, J. A., Rima, B. K. & Allsop, D., 1994, In: Journal of Neuroscience Research. 39, 4, p. 482-493 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Variability of β-amyloid protein deposited lesions in Down's syndrome brains

Ikeda, S., Tokuda, T., Yanagisawa, N., Kametani, F., Ohshima, T. & Allsop, D., 1994, In: The Tohoku Journal of Experimental Medicine. 174, 3, p. 189-198 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Amyloidosis in Alzheimer's disease

Allsop, D. & Williams, C. H., 1994, In: Biochemical Society Transactions. 22, 1, p. 171-175 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Aggregation of Alzheimer's peptides

Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 1994, In: Biochemical Society Transactions. 22, 1, p. 16S 1 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

An investigation into the proteolytic cleavage of Alzheimer amyloid precursor protein in PC-12 cells

Walsh, D. M., Williams, C. H., Kennedy, H. E. & Allsop, D., 1994, In: Biochemical Society Transactions. 22, 1, p. 14S 1 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Gelatinase A not α-secretase?

Walsh, D. M., Williams, C. H., Kennedy, H. E., Allsop, D. & Murphy, G., 1994, In: Nature. 367, 6458, p. 27-28 2 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid β/A4 peptide

Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 14/10/1993, In: Neuroscience Letters. 161, 1, p. 17-20 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Endopeptidase 3.4.24.11 converts N-1-(R,S)carboxy-3-phenylpropyl-Ala-Ala-Phe-p-carboxyanilide into a potent inhibitor of angiotensin-converting enzyme

Williams, C. H., Yamamoto, T., Walsh, D. M. & Allsop, D., 15/09/1993, In: Biochemical Journal. 294 , 3, p. 681-684 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks β/A4 amyloid immunoreactivity

Kametani, F., Tanaka, K., Ishii, T., Ikeda, S., Kennedy, H. E. & Allsop, D., 15/03/1993, In: Biochemical and Biophysical Research Communications. 191, 2, p. 392-398 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Quantification of βA4 protein deposition in the medial temporal lobe: a comparison of Alzheimer's disease and senile dementia of the Lewy body type

Gentleman, S. M., Williams, B., Royston, M. C., Jagoe, R., Clinton, J., Perry, R. H., Ince, P. G., Allsop, D., Polak, J. M. & Roberts, G. W., 3/08/1992, In: Neuroscience Letters. 142, 1, p. 9-12 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Quantitative differences in the deposition of βA4 protein in the sulci and gyri of frontal and temporal isocortex in Alzheimer's disease

Gentleman, S. M., Allsop, D., Bruton, C. J., Jagoe, R., Polak, J. M. & Roberts, G. W., 17/02/1992, In: Neuroscience Letters. 136, 1, p. 27-30 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Alzheimer amyloid β/A4 peptide binding sites and a possible 'APP-secretase' activity associated with rat brain cortical membranes

Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 14/06/1991, In: Brain Research. 551, 1-2, p. 1-9 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A monoclonal antibody to common acute lymphoblastic leukemia antigen (neutral endopeptidase) immunostains senile plaques in the brains of patients with Alzheimer's disease

Sato, M., Ikeda, K., Haga, S., Allsop, D. & Ishii, T., 2/01/1991, In: Neuroscience Letters. 121, 1-2, p. 271-273 3 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

Hardy, J. & Allsop, D., 1991, In: Trends in Pharmacological Sciences. 12, 10, p. 383-388 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Early senile plaques in Alzheimer's disease demonstrated by histochemistry, immunocytochemistry, and electron microscopy

Ikeda, S., Yanagisawa, N., Allsop, D. & Glenner, G. G., 12/1990, In: Human Pathology. 21, 12, p. 1221-1226 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons

Allsop, D., Haga, S. I., Haga, C., Ikeda, S. I., Mann, D. M. & Ishii, T., 12/1990, In: Neuropathology and Applied Neurobiology. 15, 6, p. 531-542 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The occult aftermath of boxing

Roberts, G. W., Allsop, D. & Bruton, C., 05/1990, In: Journal of Neurology, Neurosurgery and Psychiatry. 53, 5, p. 373-378 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Immunohistochemical characterization of cerebrovascular amyloid in 46 autopsied cases using antibodies to β protein and cystatin C

Maruyama, K., Ikeda, S., Ishihara, T., Allsop, D. & Yanagisawa, N., 03/1990, In: Stroke; a journal of cerebral circulation. 21, 3, p. 397-403 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Cerebral amyloid angiopathy as a cause of subarachnoid hemorrhage

Ohshima, T., Endo, T., Nukui, H., Ikeda, S., Allsop, D. & Onaya, T., 03/1990, In: Stroke; a journal of cerebral circulation. 21, 3, p. 480-483 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Neurofibrillary tangles in some cases of dementia pugilistica share antigens with amyloid β-protein of Alzheimer's disease

Allsop, D., Haga, S., Bruton, C., Ishii, T. & Roberts, G. W., 02/1990, In: American Journal of Pathology. 136, 2, p. 255-260 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The nomenclature of the cerebral amyloid fibril protein in Alzheimer's disease

Allsop, D., 01/1990, In: Neurobiology of Aging. 11, 1, p. 63-64 2 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A possible unified nomenclature for Alzheimer amyloid protein, precursors and gene

Allsop, D., 01/1990, In: Neurobiology of Aging. 11, 1, p. 69 1 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Evidence of amyloid β-protein immunoreactive early plaque lesions in Down's syndrome brains

Ikeda, S., Yanagisawa, N., Allsop, D. & Glenner, G. G., 1989, In: Laboratory Investigation. 61, 1, p. 133-137 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases: an immunohistochemical study using amyloid β-protein antibody

Ikeda, S., Allsop, D. & Glenner, G. G., 1989, In: Laboratory Investigation. 60, 1, p. 113-122 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A study of the morphology and distribution of amyloid β protein immunoreactive plaque and related lesions in the brains of Alzheimer's disease and adult Down's syndrome

Ikeda, S., Allsop, D. & Glenner, G. G., 1989, In: Progress in Clinical and Biological Research. 317, p. 313-323 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Evidence for the derivation of a peptide ligand from the amyloid β-protein precursor of Alzheimer's disease

Allsop, D., Ikeda, S. & Glenner, G. G., 1989, In: Progress in Clinical and Biological Research. 317, p. 893-902 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A demonstration of the advantages of immunostaining in the quantification of amyloid plaque deposits

Gentleman, S. M., Bruton, C., Allsop, D., Lewis, S. J., Polak, J. M. & Roberts, G. W., 1989, In: Histochemistry. 92, 4, p. 355-358 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Cerebrovascular amyloid in scrapie-affected sheep reacts with antibodies to prion protein

Allsop, D., Ikeda, S., Bruce, M. & Glenner, G. G., 5/10/1988, In: Neuroscience Letters. 92, 2, p. 234-239 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

CNS amyloid proteins in neurodegenerative diseases

Roberts, G. W., Lofthouse, R., Allsop, D., Landon, M., Kidd, M., Prusiner, S. B. & Crow, T. J., 1988, In: Neurology. 38, 10, p. 1534-40 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Immunohistochemical evidence for the derivation of a peptide ligand from the amyloid β-protein precursor of Alzheimer disease

Allsop, D., Wong, C. W., Ikeda, S., Landon, M., Kidd, M. & Glenner, G. G., 1988, In: Proceedings of the National Academy of Sciences of the United States of America. 85, 8, p. 2790-2794 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Immunogold labeling of cerebrovascular and neuritic plaque amyloid fibrils in Alzheimer's disease with an anti-β protein monoclonal antibody

Ikeda, S., Wong, C. W., Allsop, D., Landon, M., Kidd, M. & Glenner, G. G., 1987, In: Laboratory Investigation. 57, 4, p. 446-9 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Isolated senile plaque cores in Alzheimer's disease and Down's syndrome show differences in morphology

Allsop, D., Kidd, M., Landon, M. & Tomlinson, A., 1986, In: Journal of Neurology, Neurosurgery and Psychiatry. 49, 8, p. 886-892 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Monoclonal antibodies raised against a subsequence of senile plaque core protein react with plaque cores, plaque periphery and cerebrovascular amyloid in Alzheimer's disease

Allsop, D., Landon, M., Kidd, M., Lowe, J. S., Reynolds, G. P. & Gardner, A., 1986, In: Neuroscience Letters. 68, 2, p. 252-6 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Senile plaque amyloid, paired helical filaments, and cerebrovascular amyloid in Alzheimer's disease are all deposits of the same protein

Kidd, M., Allsop, D. & Landon, M., 1985, In: Lancet. 1, 8423, p. 278

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The isolation and amino acid composition of senile plaque core protein

Allsop, D., Landon, M. & Kidd, M., 1983, In: Experimental Brain Research. 259, 2, p. 348-52 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

β(A4)-amyloid protein and parkinsonian dementia complex of Guam

Gentleman, S. M., Perl, D., Allsop, D., Clinton, J., Royston, M. C. & Roberts, G. W., 5/01/1991, In: Lancet. 337, 8732, p. 55-56 2 p.

Research output: Contribution to Journal/Magazine › Letter › peer-review

Amyloid β-peptide and Alzheimer's disease

Allsop, D. & Mayes, J., 18/08/2014, In: Essays in Biochemistry. 56, p. 99-110 12 p., 7.

Research output: Contribution to Journal/Magazine › Literature review › peer-review

Modulation of β-amyloid production and fibrillisation

Allsop, D., Twyman, L., Davies, Y., Moore, S., York, A., Swanson, L. & Soutar, I., 2000, In: Biochemical Society Symposia. 67, p. 1-14 14 p.

Research output: Contribution to Journal/Magazine › Literature review › peer-review

Phosphorylated α-synuclein as a potential biomarker for Parkinson's disease (Editorial)

Foulds, P., Mann, D. & Allsop, D., 2012, In: Expert Review of Molecular Diagnostics. 12, 2, p. 115-117 3 p.

Research output: Contribution to Journal/Magazine › Editorial

Untangled - peptide-based inhibitors of tau aggregation as a potential treatment for Alzheimer's disease

Allsop, D., Aggidis, A., Fullwood, N. J., Taylor, M. N., Foulds, P., Vincent, S. & Dale, M., 2018, In: Journal of Prevention of Alzheimer's Disease. 5, Suppl 1, p. S15-S16 2 p.

Research output: Contribution to Journal/Magazine › Meeting abstract

A novel approach to the therapy of Alzheimer's disease based on peptide nanoliposome inhibitors of Aβ and tau aggregation

Allsop, D., Taylor, M. N., Fullwood, N. J., Michael, M., Aggidis, A., Vincent, S. & Dale, M., 1/11/2017, In: Journal of Prevention of Alzheimer's Disease. 4, 4, p. 385-386 2 p.

Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review