Acceleration of gelation and promotion of mineralization of chitosan hydrogels by alkaline phosphatase

Douglas, T. E. L., Skwarczynska, A., Modrzejewska, Z., Balcaen, L., Schaubroeck, D., Lycke, S., Vanhaecke, F., Vandenabeele, P., Dubruel, P., Jansen, J. A. & Leeuwenburgh, S. C. G., 05/2013, In: International Journal of Biological Macromolecules. 56, p. 122-132 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Amine-Rich Coatings to Potentially Promote Cell Adhesion, Proliferation and Differentiation, and Reduce Microbial Colonization: Strategies for Generation and Characterization

Martocq, L. & Douglas, T., 18/08/2021, In: Coatings. 11, 8, 19 p., 983.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

ANN prediction of corrosion behaviour of uncoated and biopolymers coated cp-Titanium substrates

Kumari, S., Tiyyagura, H. R., Douglas, T. E. L., Mohammed, E. A. A., Adriaens, A., Fuchs-Godec, R., Mohan, M. K. & Skirtach, A. G., 5/11/2018, In: Materials and Design. 157, p. 35-51 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Application of whey protein isolate in bone regeneration: Effects on growth and osteogenic differentiation of bone-forming cells

Douglas, T. E. L., Vandrovcová, M., Kročilová, N., Keppler, J. K., Zárubová, J., Skirtach, A. G. & Bačáková, L., 01/2018, In: Journal of Dairy Science. 101, 1, p. 28-36 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Biomimetic biphasic curdlan-based scaffold for osteochondral tissue engineering applications: Characterization and preliminary evaluation of mesenchymal stem cell response in vitro

Klimek, K., Benko, A., Vandrovcová, M., Travnickova, M., Douglas, T., Tarczynska, M., Broz, A., Gaweda, K., Ginalska, G. & Bacakova, L., 30/04/2022, In: Biomaterials Advances. 135, 19 p., 212724.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Biosurfactants as foaming agents in calcium phosphate bone cements

Cichon, E., Czechowska, J., Krok-Borkowicz, M., Allinson, S., Stepien, K., Smith, A., Pamula, E., Douglas, T. & Zima, A., 28/02/2023, In: Biomaterials Advances. 145, 14 p., 213273.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Ca:Mg:Zn:CO3 and Ca:Mg:CO3-tri- and bi-elemental carbonate microparticles for novel injectable self-gelling hydrogel-microparticle composites for tissue regeneration

Douglas, T. E. L., Sobczyk, K., Łapa, A., Włodarczyk, K., Brackman, G., Vidiasheva, I., Reczyńska, K., Pietryga, K., Schaubroeck, D., Bliznuk, V., Van Der Voort, P., Declercq, H., Van den Bulcke, J., Samal, S. K., Khalenkow, D., Parakhonskiy, B., Van Acker, J., Coenye, T., Lewandowska-Szumieł, M., Pamuła, E., & 1 othersSkirtach, A., 24/03/2017, In: Biomedical Materials. 12, 2, 13 p., 025015.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Chitosan hydrogels enriched with polyphenols: Antibacterial activity, cell adhesion and growth and mineralization

Liskova, J., Douglas, T. E. L., Beranova, J., Skwarczynska, A., Bozic, M., Samal, S. K., Modrzejewska, Z., Gorgieva, S., Kokol, V. & Bacakova, L., 20/09/2015, In: Carbohydrate Polymers. 129, p. 135-142 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

CIEKAWOŚĆ TO NAJWAŻNIEJSZY KLUCZ DO SUKCESU: Rozmowa z dr. Timothy Douglasem z Lancaster University o zamiłowaniu do zgłębiania wiedzy i trudnościach badacza w czasie pandemii

Douglas, T., 15/12/2021, In: Inżynieria Materiałowa (Materials Engineering). 4-5

Research output: Contribution to Journal/Magazine › Journal article

Complex Material and Surface Analysis of Anterolateral Distal Tibial Plate of 1.4441 Steel

Hlinka, J., Dostalova, K., Dedkova, K. P., Madeja, R., Frydrysek, K., Koutecky, J., Sova, P. & Douglas, T., 27/12/2021, In: Metals. 12, 1, 14 p., e60.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Composites Based on Hydroxyapatite and Whey Protein Isolate for Applications in Bone Regeneration

Slota, D., Glab, M., Tyliszczak, B., Douglas, T., Rudnicka, K., Miernik, K., Urbaniak, M., Rusek-Wala, P. & Sobczak-Kupiec, A., 29/04/2021, In: Materials. 14, 9, 2317.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Composites of gellan gum hydrogel enzymatically mineralized with calcium-zinc phosphate for bone regeneration with antibacterial activity.

Douglas, T. E. L., Pilarz, M., Lopez-Heredia, M., Brackman, G., Schaubroeck, D., Balcaen, L., Bliznuk, V., Dubruel, P., Knabe-Ducheyne, Vanhaecke, F., Coenye, T. & Pamula, E., 05/2017, In: Journal of Tissue Engineering and Regenerative Medicine. 11, 5, p. 1610-1618 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Could Curdlan/Whey Protein Isolate/Hydroxyapatite Biomaterials Be Considered as Promising Bone Scaffolds?—Fabrication, Characterization, and Evaluation of Cytocompatibility towards Osteoblast Cells In Vitro

Klimek, K., Palka, K., Truszkiewicz, W., Douglas, T., Nurzynska, A. & Ginalska, G., 16/10/2022, In: Cells. 11, 20, 19 p., 3251.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Dairy-inspired coatings for bone implants from whey protein isolate-derived self-assembled fibrils

Rabe, R., Hempel, U., Martocq, L., Keppler, J. K., Aveyard, J. & Douglas, T., 3/08/2020, In: International Journal of Molecular Sciences. 21, 15, 7 p., 5544.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Designing of Gradient Scaffolds and their Applications in Tissue Regeneration

Pattnaik, A., Sanket, A. S., Pradhan, S., Sahoo, R., Das, S., Pany, S., Douglas, T., Dandela, R., Liu, Q., Rajadas, J., Pati, S., De Smedt, S., Braeckmans, K. & Samal, S. K., 31/05/2023, In: Biomaterials. 296, 34 p., 122078.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Development of Thermosensitive Hydrogels of Chitosan, Sodium and Magnesium Glycerophosphate for Bone Regeneration Applications

Liskova, J., Bacakova, L., Skwarczynska, A. L., Musial, O., Bliznuk, V., De Schamphelaere, K., Modrzejewska, Z. & Douglas, T. E. L., 06/2015, In: Journal of Functional Biomaterials. 6, 2, p. 192-203 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Dissolved organic carbon and biodegradable dissolved organic carbon determination in river water of the Strug Basin

Piech, A., Trzyna, K., Skwarczynska-Wojsa, A. L. & Douglas, T., 31/03/2019, In: JOURNAL OF CIVIL ENGINEERING, ENVIRONMENT AND ARCHITECTURE. 36, 1, p. 27-35 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Effect of low-temperature plasma treatment of electrospun polycaprolactone fibrous scaffolds on calcium carbonate mineralisation

Ivanova, A., Syromotina, D., Shkarina, S., Shkarin, R., Cecilia, A., Weinhardt, V., Baumbach, T., Saveleva, M., Gorin, D., Douglas, T. E. L., Parakhonskiy, B., Skirtach, A. G., Cools, P., De Geyter, N., Morent, R., Oehr, C., Surmeneva, M. & Surmenev, R., 22/11/2018, In: RSC Advances. 8, 68, p. 39106-39114 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Electron Beam-Treated Enzymatically Mineralized Gelatin Hydrogels for Bone Tissue Engineering

Riedel, S., Ward, D., Kudlackova, R., Mazur, K., Bačáková, L., Kerns, J., Allinson, S., Ashton, L., Koniezcny, R., Mayr, S. & Douglas, T., 8/10/2021, In: Journal of Functional Biomaterials. 12, 4, p. 1-17 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Electrospun polycaprolactone membranes with Zn-doped bioglass for nasal tissues treatment

Rajzer, I., Dziadek, M., Kurowska, A., Cholewa-Kowalska, K., Ziabka, M., Menaszek, E. & Douglas, T., 1/07/2019, In: Journal of Materials Science: Materials in Medicine. 30, 11 p., 80.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Electrospun Produced 3D Matrices for Covering of Vascular Stents: Paclitaxel Release Depending on Fiber Structure and Composition of the External Environment

Kuznetsov, K., Stepanova, A., Kvon, R., Douglas, T. E. L., Kuznetsov, N., Chernonosova, V., Zaporozhchenko, I., Kharkova, M., Romanova, I., Karpenko, A. & Laktionov, P., 2/11/2018, In: Materials. 11, 11, 16 p., 2176.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Endothelialization of Whey Protein Isolate-Based Scaffolds for Tissue Regeneration

Genç, H., Friedrich, B., Alexiou, C., Pietryga, K., Cicha, I. & Douglas, T., 12/10/2023, In: Molecules. 28, 20, 7052.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Enhancement of biomimetic enzymatic mineralization of gellan gum polysaccharide hydrogels by plant-derived gallotannins

Douglas, T., Keppler, J. K., Vandrovcova, M., Plnencer, M., Beranova, J., Feuereisen, M., Parakhonskiy, B. V., Svenskaya, Y., Atkin, V., Ivanova, A., Ricquier, P., Balcaen, L., Vanhaecke, F., Schieber, A., Bacakova, L. & Skirtach, A. G., 27/03/2020, In: International Journal of Molecular Sciences. 21, 7, 18 p., 2315.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Enrichment of chitosan hydrogels with perfluorodecalin promotes gelation and stem cell vitality

Douglas, T. E. L., Pilarek, M., Kalaszczynska, I., Senderek, I., Skwarczynska, A., Cuijpers, V. M. J. I., Modrzejewska, Z., Lewandowska-Szumiel, M. & Dubruel, P., 1/08/2014, In: Materials Letters. 128, p. 79-84 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Enrichment of enzymatically mineralized gellan gum hydrogels with phlorotannin-rich Ecklonia cava extract Seanol(®) to endow antibacterial properties and promote mineralization

Douglas, T. E. L., Dokupil, A., Reczyńska, K., Brackman, G., Krok-Borkowicz, M., Keppler, J. K., Božič, M., Van Der Voort, P., Pietryga, K., Samal, S. K., Balcaen, L., van den Bulcke, J., Van Acker, J., Vanhaecke, F., Schwarz, K., Coenye, T. & Pamuła, E., 10/08/2016, In: Biomedical Materials. 11, 4, 13 p., 045015.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Enzymatic mineralization of gellan gum hydrogel for bone tissue-engineering applications and its enhancement by polydopamine

Douglas, T. E. L., Wlodarczyk, M., Pamula, E., Declercq, H., de Mulder, E., Bucko, M., Balcaen, L., Vanhaecke, F., Cornelissen, R., Dubruel, P., Jansen, J. & Leeuwenburgh, S., 1/11/2014, In: Journal of Tissue Engineering and Regenerative Medicine. 8, 11, p. 906-918 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Enzymatic Mineralization of Hydrogels for Bone Tissue Engineering by Incorporation of Alkaline Phosphatase

Douglas, T. E. L., Messersmith, P. B., Chasan, S., Mikos, A. G., de Mulder, E. L. W., Dickson, G., Schaubroeck, D., Balcaen, L., Vanhaecke, F., Dubruel, P., Jansen, J. A. & Leeuwenburgh, S. C. G., 08/2012, In: Macromolecular Bioscience. 12, 8, p. 1077-1089 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Enzymatic, urease-mediated mineralization of gellan gum hydrogel with calcium carbonate, magnesium-enriched calcium carbonate and magnesium carbonate for bone regeneration applications.

Douglas, T. E. L., Lapa, A., Samal, S., Declercq, H., Declercq, H., Schaubroeck, D., Mendes, A., Van der Voort, P., Dokupil, A., Plis, A., De Schamphelaere, K., Chronakis, I., Pamula, E. & Skirtach, A., 12/2017, In: Journal of Tissue Engineering and Regenerative Medicine. p. 3556-3566 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Enzymatically biomineralized chitosan scaffolds for tissue-engineering applications

Dash, M., Samal, S. K., Douglas, T. E. L., Schaubroeck, D., Leeuwenburgh, S. C., Voort, P. V. D., Declercq, H. A. & Dubruel, P., 1/05/2017, In: Journal of Tissue Engineering and Regenerative Medicine. 11, 5, p. 1500-1513 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Freeze-dried curdlan/whey protein isolate-based biomaterial as promising scaffold for matrix-associated autologous chondrocyte transplantation – A pilot in vitro study

Klimek, K., Tarczynska, M., Truszkiewicz, W., Gaweda, K., Douglas, T. & Ginalska, G., 14/01/2022, In: Cells. 11, 2, 16 p., e282.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Functionalization of additive-manufactured Ti6Al4V scaffolds with poly(allylamine hydrochloride)/poly(styrene sulfonate) bilayer microcapsule system containing dexamethasone

Chudinova, E., Koptyug, A., Mukhortova, Y., Pryadko, A., Volkova, A., Ivanov, A., Plotnikov, E., Khan, Y., Epple, M., Sokolova, V., Prymak, O., Douglas, T., Surmenev, R. & Surmeneva, M., 15/11/2021, In: Materials Chemistry and Physics. 273, 14 p., 125099.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Generation of composites for bone tissue-engineering applications consisting of gellan gum hydrogels mineralized with calcium and magnesium phosphate phases by enzymatic means

Douglas, T. E. L., Krawczyk, G., Pamula, E., Declercq, H., Schaubroeck, D., Bucko, M., Balcaen, L., Van der Voort, P., Bliznuk, V., van den Vreken, N., Dash, M., Detsch, R., Boccaccini, A., Vanhaecke, F., Cornelissen, R. & Dubruel, 11/2016, In: Journal of Tissue Engineering and Regenerative Medicine. 10, 11, p. 938-954 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Generation of pearl/Calcium phosphate composite particles and their integration into porous chitosan scaffolds for bone regeneration

Li, Z., Rehman, I. U., Shepherd, R. & Douglas, T., 29/02/2024, In: Journal of Functional Biomaterials. 15, 3, 20 p., 55.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Heparin Enriched-WPI Coating on Ti6Al4V Increases Hydrophilicity and Improves Proliferation and Differentiation of Human Bone Marrow Stromal Cells

Facchetti, D., Hempel, U., Martocq, L., Smith, A., Koptyug, A., Surmenev, R., Surmeneva, M. & Douglas, T., 23/12/2021, In: International Journal of Molecular Sciences. 23, 1, 12 p., e139.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Hierarchy of hybrid materials – the place of inorganics-in-organics in it, their composition and applications

Saveleva, M., Eftekhari, K., Abalymov, A., Douglas, T. E. L., Volodkin, D., Parakhonskiy, B. V. & Skirtach, A. G., 4/04/2019, In: Frontiers in Chemistry. 7, 21 p., 179.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Investigations on the impact of the introduction of the Aloe vera into the hydrogel matrix on cytotoxic and hydrophilic properties of these systems considered as potential wound dressings

Kudlacik-Kramarczyk, S., Drabczyk, A., Glab, M., Alves De Lima, D., Lin, H., Douglas, T., Kuciel, S., Zagorska, A. & Tyliszczak, B., 30/04/2021, In: Materials Science and Engineering: C . 123, 12 p., 111977.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Marine Polysaccharide-Collagen Coatings on Ti6Al4V Alloy Formed by Self-Assembly

Norris, K., Mishukova, O., Zykwinska, A., Colliec-Jouault, S., Sinquin, C., Koptioug, A., Cuenot, S., Kerns, J. G., Surmeneva, M., Surmenev, R. & Douglas, T. E. L., 19/01/2019, In: Micromachines. 10, 1, 10 p., 68.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Marine-inspired enzymatic mineralization of dairy-derived whey protein isolate (WPI) hydrogels for bone tissue regeneration

Norris, K., Kocot, M., Tryba, A-M., Chai, F., Talari, A., Ashton, L., Parakhonskiy, B., Samal, S. K., Blanchemain, N., Pamula, E. & Douglas, T., 2/06/2020, In: Marine Drugs . 18, 6, 13 p., 294.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Mineralization of gellan gum hydrogels with calcium and magnesium carbonates by alternate soaking for bone regeneration applications

Lopez-Heredia, M., Lapa, A., Reczynska, K., Pietryga, K., Balcaen, L., Mendes, A., Schaubroeck, D., Van der Voort, P., Dokupil, A., Plis, A., Stevens, C., Parakhonskiy, B., Samal, S., Vanhaecke, F., Chai, F., Chronakis, I., Blanchemain, N., Pamula, E., Skirtach, A. G. & Douglas, T. E. L., 08/2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 8, p. 1825-1834 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Modification of heat-induced whey protein isolate hydrogel with highly bioactive glass particles results in promising biomaterial for bone tissue engineering

Dziadek, M., Charuza, K., Kudlackova, R., Aveyard, J., D'Sa, R., Serafim, A., Stancu, I-C., Iovu, H., Kerns, J., Allinson, S., Dziadek, K., Szatkowski, P., Cholewa-Kowalska, K., Bacakova, L., Pamula, E. & Douglas, T., 31/07/2021, In: Materials and Design. 205, 14 p., 109749.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Morphological, mechanical and mucoadhesive properties of electrospun chitosan/phospholipid hybrid nanofibers

Mendes, A. C., Moreno, J. S., Hanif, M., Douglas, T. E. L., Chen, M. & Chronakis, I. S., 2/08/2018, In: International Journal of Molecular Sciences. 19, 8, 16 p., 2266.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Newly crosslinked chitosan- and chitosan-pectin-based hydrogels with high antioxidant and potential anticancer activity

Dziadek, M., Dziadek, K., Salagierski, S., Drozdowska, M., Serafim, A., Stancu, I-C., Szatkowski, P., Kopec, A., Rajzer, I., Douglas, T. & Cholewa-Kowalska, K., 15/08/2022, In: Carbohydrate Polymers. 290, 12 p., 119486.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Novel injectable gellan gum hydrogel composites incorporating Zn- and Sr-enriched bioactive glass microparticles: high-resolution X-Ray micro-computed tomography, antibacterial and in vitro testing

Douglas, T. E. L., Dziadek, M., Gorodzha, S., Liskova, J., Brackman, G., Vanhoorne, V., Vervaet, C., Balcaen, L., del Rosario Florez Garcia, M., Boccaccini, A., Weinhardt, V., Baumbach, T., Vanhaecke, F., Coenye, T., Bacakova, L., Surmeneva, M., Surmenev, R., Cholewa-Kowalska, K. & Skirtach, A., 06/2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 6, p. 1313-1326 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Novel multicomponent organic-inorganic WPI/gelatin/CaP hydrogel composites for bone tissue engineering

Dziadek, M., Kudlackova, R., Zima, A., Slosarczyk, A., Ziabka, M., Jelen, P., Shkarina, S., Cecilia, A., Zuber, M., Surmeneva, M., Surmenev, R., Bačáková, L., Cholewa-Kowalska, K. & Douglas, T., 30/11/2019, In: Journal of Biomedical Materials Research Part A. 107, 11, p. 2479-2491 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Novel naturally derived whey protein isolate and aragonite biocomposite hydrogels have potential for bone regeneration

Gupta, D., Kocot, M., Tryba, A-M., Serafim, A., Stancu, I-C., Jaegermann, Z., Pamula, E., Reilly, G. C. & Douglas, T., 1/03/2020, In: Materials and Design. 188, 11 p., 108408.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Novel self-gelling injectable hydrogel/alpha-tricalcium phosphate composites for bone regeneration: Physiochemical and microcomputer tomographical characterization

Douglas, T. E. L., Schietse, J., Zima, A., Gorodzha, S., Parakhonskiy, B., Khalenkow, D., Shkarin, R., Ivanova, A., Baumbach, T., Weinhardt, V., Stevens, C., Vanhoorne, V., Vervaet, C., Balcaen, L., Vanhaecke, F., Slosarczyk, A., Surmeneva, M., Surmenev, R. & Skirtach, A., 03/2018, In: Journal of Biomedical Materials Research Part A. 106, 3, p. 822-828 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Novel whey protein isolate-based highly porous scaffolds modified with therapeutic ion-releasing bioactive glasses

Dziadek, M., Douglas, T., Dziadek, K., Zagrajczuk, B., Serafim, A., Stancu, I-C. & Cholewa-Kowalska, K., 15/02/2020, In: Materials Letters. 261, 5 p., 127115.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Pectin coatings on titanium alloy scaffolds produced by additive manufacturing: Promotion of human bone marrow stromal cell proliferation

Douglas, T. E. L., Hempel, U., Zydek, J., Vladescu, A., Pietryga, K., Kaeswurm, J., Buchweitz, M., Surmenev, R., Surmeneva, M., Cotrut, C., Koptyug, A. & Pamula, E., 15/09/2018, In: Materials Letters. 227, p. 225-228 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Pectin-bioactive glass self-gelling, injectable composites with high antibacterial activity

Douglas, T. E. L., Dziadek, M., Schietse, J., Boone, M., Declercq, H., Coenye, T., Vanhoorne, V., Vervaet, C., Balcaen, L., Buchweitz, M., Vanhaecke, F., Van Assche, F., Cholewa-Kowalska, K. & Skirtach, A. G., 1/02/2019, In: Carbohydrate Polymers. 205, p. 427-436 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review