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Biomedical and Life Sciences

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  1. 2022
  2. Published

    Aggressive uveal melanoma displays a high degree of centrosome amplification, opening the door to therapeutic intervention

    Sabat‐Pośpiech, D., Fabian‐Kolpanowicz, K., Kalirai, H., Kipling, N., Coupland, S. E., Coulson, J. M. & Fielding, A. B., 31/07/2022, In: The Journal of Pathology: Clinical Research. 8, 4, p. 383-394 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Possible mechanisms and biomarkers of resistance to vismodegib in SHH medulloblastoma

    Roesler, R., de Farias, C. B., Brunetto, A. T., Gregianin, L., Jaeger, M., Nör, C. & Thomaz, A., 31/07/2022, In: Neuro-Oncology. 24, 7, p. 1210–1211 2 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Reduced cutaneous CD200:CD200R1 signaling in psoriasis enhances neutrophil recruitment to skin

    Linley, H., Jaigirdar, S., Mohamed, K., Griffiths, C. E. M. & Saunders, A., 31/07/2022, In: Immunity, Inflammation and Disease. 10, 7, 14 p., e648.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Graphia: A platform for the graph-based visualisation and analysis of high dimensional data

    Freeman, T. C., Horsewell, S., Patir, A., Harling-Lee, J., Regan, T., Shih, B. B., Prendergast, J., Hume, D. A. & Angus, T., 25/07/2022, In: PLoS Computational Biology. 18, 7, e1010310.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Reduced Insulin Signalling Targeted to Serotonergic Neurons but Not Other Neuronal Subtypes Extends Lifespan in Drosophila melanogaster

    Dravecz, N., Shaw, T., Davies, I., Brown, C., Ormerod, L., Vu, G., Walker, T., Taank, T., Shirras, A. & Broughton, S., 5/07/2022, In: Frontiers in Aging Neuroscience. 14, 16 p., 893444.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition

    Menzies, S. K., Dawson, C. A., Crittenden, E., Edge, R. J., Hall, S. R., Alsolaiss, J., Wilkinson, M. C., Casewell, N. R., Harrison, R. A. & Ainsworth, S., 5/07/2022, In: Scientific Reports. 12, 1, p. 11328

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    ‘Making the dust fly’: (A case study of) design research promoting health and sustainability in addressing household infections

    Tsekleves, E., Ahorlu, C., Darby, A., Pickup, R., de Souza, D. & Boakye, D., 3/07/2022, DRS2022 Bilbao: Design Research Society Conference 2022. Design Research Society, 21 p. 317. (DRS2022 Bilbao: Design Research Society Conference 2022).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  9. Published

    An In-depth Proteomic Map of Leishmania donovani Isolate from Post Kala-azar Dermal Leishmaniasis (PKDL) Patient

    Routaray, C. B., Kumar, A., Sundar, S., Sathe, G., Pawar, H. & Pai, K., 30/06/2022, In: Acta Parasitologica. 67, 2, p. 687-696 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Clinical frailty, and not features of acute infection, is associated with late mortality in COVID-19: a retrospective cohort study

    Vlachogiannis, N. I., Baker, K. F., Georgiopoulos, G., Lazaridis, C., van der Loeff, I. S., Hanrath, A. T., Sopova, K., Tual-Chalot, S., Gatsiou, A., Spyridopoulos, I., Stamatelopoulos, K., Duncan, C. J. A. & Stellos, K., 30/06/2022, In: Journal of Cachexia, Sarcopenia and Muscle. 13, 3, p. 1502-1513 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms

    Alomran, N., Blundell, P., Alsolaiss, J., Crittenden, E., Ainsworth, S., Dawson, C. A., Edge, R. J., Hall, S. R., Harrison, R. A., Wilkinson, M. C., Menzies, S. K. & Casewell, N. R., 29/06/2022, In: Toxins. 14, 7, 443.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Single locus phosphoproteomics reveals phosphorylation of RPA-1 is required for generation of single-strand DNA following a break at a subtelomeric locus

    McLaughlin, E., Dujeancourt-Henry, A., Chaze, T., Gianetto, Q. G., Matondo, M., Urbaniak, M. D. & Glover, L., 15/06/2022, bioRxiv.

    Research output: Working paper › Preprint

  13. Published

    Asgard archaea shed light on the evolutionary origins of the eukaryotic ubiquitin-ESCRT machinery

    Hatano, T., Palani, S., Papatziamou, D., Salzer, R., Souza, D. P., Tamarit, D., Makwana, M., Potter, A., Haig, A., Xu, W., Townsend, D., Rochester, D., Bellini, D., Hussain, H. M. A., Ettema, T. J. G., Löwe, J., Baum, B., Robinson, N. P. & Balasubramanian, M., 13/06/2022, In: Nature Communications. 13, 1, 16 p., 3398.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Aberrant IL-17 levels in rodent models of Autism Spectrum Disorder: a systematic review

    Thawley, A. J., Veneziani, L., Rabelo-da-Ponte, F. D., Riederer, I., Mendes Da Cruz, D. A. & Bambini Junior, V., 10/06/2022, In: Frontiers in Immunology. 13, 12 p., 874064.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Extracellular release of two peptidases dominates generation of the trypanosome quorum-sensing signal

    Tettey, M. D., Rojas, F. & Matthews, K. R., 9/06/2022, In: Nature Communications. 13, 1, 14 p., 3322.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Mistargeting of aggregation prone mitochondrial proteins activates a nucleus-mediated posttranscriptional quality control pathway in trypanosomes

    Dewar, C. E., Oeljeklaus, S., Mani, J., Muehlhaeuser, W. W. D., von Kaenel, C., Zimmermann, J., Ochsenreiter, T., Warscheid, B. & Schneider, A., 2/06/2022, In: Nature Communications. 13, 3084.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Development of CRISPR/Cas9-based Novel Vaccines against Poultry Viruses

    Vilela, J. & Munir, M., 27/05/2022, In: Access Microbiology. 4, 5

    Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review

  18. Published

    Nanoformulated Bumetanide Ameliorates Social Deficiency in BTBR Mice Model of Autism Spectrum Disorder

    Lv, H., Gu, X., Shan, X., Zhu, T., Ma, B., Zhang, H.-T., Bambini-Junior, V., Zhang, T., Li, W.-G., Gao, X. & Li, F., 23/05/2022, In: Frontiers in Immunology. 13, 13 p., 870577.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Effect of Escitalopram on the Number of DCX-Positive Cells and NMUR2 Receptor Expression in the Rat Hippocampus under the Condition of NPSR Receptor Blockade

    Piwowarczyk-Nowak, A., Pałasz, A., Suszka-Świtek, A., Błaszczyk, I., Bogus, K., Łasut-Szyszka, B., Krzystanek, M. & Worthington, J. J., 20/05/2022, In: Pharmaceuticals. 15, 5, 14 p., 631.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    Selective Wee1 degradation by PROTAC degraders recruiting VHL and CRBN E3 ubiquitin ligases

    Aublette, M. C., Harrison, T. A., Thorpe, E. J. & Gadd, M. S., 15/05/2022, In: Bioorganic & medicinal chemistry letters. 64, 8 p., 128636.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions

    Zárate-Potes, A., Ali, I., Ribeiro Camacho, M., Brownless, H. & Benedetto, A., 10/05/2022, In: Frontiers in Microbiology. 13, 17 p., 853629.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    Editorial: The Neurovascular Unit as a Potential Biomarker and Therapeutic Target in Cerebrovascular Disease

    Nizari, S., Hawkes, C. A., Hattori, Y. & Mishra, A., 5/05/2022, In: Frontiers in Aging Neuroscience. 14, 2 p., 908716.

    Research output: Contribution to Journal/Magazine › Editorial › peer-review

  23. Published

    The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei

    Iyer, A., Niemann, M., Serricchio, M., Dewar, C. E., Oeljeklaus, S., Farine, L., Warscheid, B., Schneider, A. & Bütikofer, P., 2/05/2022, In: PLoS Pathogens. 18, 5, e1009717.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Altered medial prefrontal cortex and dorsal raphé activity predict genotype and correlate with abnormal learning behaviour in a mouse model of autism-associated 2p16.3 deletion

    Hughes, R., Whittingham-Dowd, J., Clapcote, S., Broughton, S. & Dawson, N., 30/04/2022, In: Autism Research. 15, 4, p. 614-627 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Characterization of a highly diverged mitochondrial ATP synthase Fo subunit in Trypanosoma brucei

    Dewar, C. E., Oeljeklaus, S., Wenger, C., Warscheid, B. & Schneider, A., 30/04/2022, In: Journal of Biological Chemistry. 298, 4, 101829.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. Published

    High-Throughput Screening of Microbial Isolates with Impact on Caenorhabditis elegans Health

    Ali, I., Martin, J., Zárate-Potes, A. & Benedetto, A., 28/04/2022, In: Journal of Visualized Experiments. 2022, 182, e63860.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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