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Medical and Social Statistics

  1. Journal article
  2. Published

    Optimal design when outcome values are not missing at random

    Lee, K., Mitra, R. & Biedermann, S., 1/10/2018, In: Statistica Sinica. 28, 4, p. 1821-1838 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. E-pub ahead of print

    Software Application Profile: mrrobust - A Tool For Performing Two-Sample Summary Mendelian Randomization Analyses

    Spiller, W., Davies, N. & Palmer, T. M., 12/09/2018, (E-pub ahead of print) In: International Journal of Epidemiology.

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Performance of different clinical trial designs to evaluate treatments during an epidemic

    Brueckner, M., Titman, A. C., Jaki, T. F., Rojek, A. & Horby, P. W., 11/09/2018, In: PLoS ONE. 13, 9, 19 p., e0203387.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Bayesian spatial monotonic multiple regression

    Rohrbeck, C., Costain, D. A. & Frigessi, A., 1/09/2018, In: Biometrika. 105, 3, p. 691-707 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    A proposal for a new PhD level curriculum on quantitative methods for drug development

    Jaki, T. F., Gordon, A., Forster, P. S., Bijnens, L., Bornkamp, B., Brannath, W., Fontana, R., Gasparini, M., Hampson, L. V., Jacobs, T., Jones, B., Paoletti, X., Posch, M., Titman, A. C., Vonk, R. & Koenig, F., 09/2018, In: Pharmaceutical Statistics. 17, 5, p. 593-606 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Dose-escalation strategies which utilise subgroup information

    Cotterill, A. & Jaki, T. F., 09/2018, In: Pharmaceutical Statistics. 17, 5, p. 414-436 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Model selection based on combined penalties for biomarker identification

    Vradi, E., Brannath, W., Jaki, T. & Vonk, R., 4/07/2018, In: Journal of Biopharmaceutical Statistics. 28, 4, p. 735-749 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. E-pub ahead of print

    An information-theoretic Phase I/II design for molecularly targeted agents that does not require an assumption of monotonicity

    Mozgunov, P. & Jaki, T. F., 15/06/2018, (E-pub ahead of print) In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 68, 2, p. 347-367 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Attachment and therapeutic alliance in psychological therapy for people with recent onset psychosis who use cannabis

    Berry, K., Palmer, T. M., Gregg, L., Barrowclough, C. & Lobban, A. F., 6/06/2018, In: Clinical Psychology and Psychotherapy. 25, 3, p. 440-445 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    UK Families with Children with Rare Chromosome Disorders: Changing Experiences of Diagnosis and Counseling (2003 to 2013)

    Szczepura, A., Wynn, S., Searle, B., Khan, A., Palmer, T. M., Biggerstaff, D., Elliott, J. & Hulten, M., 05/2018, In: Clinical Genetics. 93, 5, p. 972-981 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Instrumental variable methods for a binary outcome were used to informatively address non-compliance in a randomised trial in surgery

    Cook, J. A., Maclennan, G. S., Palmer, T., Lois, N. & Emsley, R., 04/2018, In: Journal of Clinical Epidemiology. 96, p. 126-132 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    A review of the deterministic and diffusion approximations for stochastic chemical reaction networks

    Mozgunov, P., Beccuti, M., Horvath, A., Jaki, T. F., Sirovich, R. & Bibbona, E., 04/2018, In: Reaction Kinetics, Mechanisms and Catalysis. 123, 2, p. 289-312 24 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Reading comprehension difficulties in children with rolandic epilepsy

    Currie, N. K., Lew, A. R., Palmer, T. M., Basu, H., De Goede, C., Ayer, A. & Cain, K., 03/2018, In: Developmental Medicine and Child Neurology. 60, 3, p. 275-282 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published
  16. Published

    Extrapolation of efficacy and other data to support the development of new medicines for children: a systematic review of methods

    Wadsworth, I., Hampson, L. V. & Jaki, T. F., 1/02/2018, In: Statistical Methods in Medical Research. 27, 2, p. 398-413 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    PET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-d-glucose positron emission tomography with computed tomography scanning in the diagnosis and management of pancreatic cancer

    Ghaneh, P., Hanson, R., Titman, A., Lancaster, G. A., Plumpton, C., Lloyd-Williams, H., Yeo, S. T., Edwards, R. T., Johnson, C., Abu Hilal, M., Higginson, A. P., Armstrong, T., Smith, A., Scarsbrook, A., McKay, C., Carter, R., Sutcliffe, R. P., Bramhall, S., Kocher, H. M., Cunningham, D. & 20 others, Pereira, S. P., Davidson, B., Chang, D., Khan, S., Zealley, I., Sarker, D., Al Sarireh, B., Charnley, R., Lobo, D., Nicolson, M., Halloran, C., Raraty, M., Sutton, R., Vinjamuri, S., Evans, J., Campbell, F., Deeks, J., Sanghera, B., Wong, W-L. & Neoptolemos, J. P., 02/2018, In: Health Technology Assessment. 22, 7, p. 1-114 114 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    A review of statistical updating methods for clinical prediction models

    Su, T-L., Jaki, T. F., Hickey, G., Buchan, I. & Sperrin, M., 1/01/2018, In: Statistical Methods in Medical Research. 27, 1, p. 185-197 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Identification of Predicted Individual Treatment Effects (PITE) in randomized clinical trials

    Lamont, A. E., Lyons, M., Jaki, T. F., Stuart, E. A., Feaster, D., Ishwaran, H., Tharmaratnam, K. & Van Horn, M. L., 1/01/2018, In: Statistical Methods in Medical Research. 27, 1, p. 142-157 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    Optimal Designs for Non-Compartmental Analysis of Pharmacokinetic Studies

    Barnett, H. Y., Geys, H., Jacobs, T. & Jaki, T. F., 2018, In: Statistics in Biopharmaceutical Research. 10, 4, p. 255-263 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Patterns of routine primary care for osteoarthritis in the UK: a cross-sectional electronic health records study

    Jackson, H., Barnett, L., Jordan, K., Dziedzic, K., Cottrell, E., Finney, A., Paskins, Z. & Edwards, J., 29/12/2017, In: BMJ Open. 7, 12, 11 p., e019694.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Simultaneous confidence regions for multivariate bioequivalence

    Pallmann, P. S. & Jaki, T. F., 20/12/2017, In: Statistics in Medicine. 36, 29, p. 4585-4603 19 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Simultaneous comparisons of treatments at multiple time points: combined marginal models versus joint modeling

    Pallmann, P., Pretorius, M. & Ritz, C., 1/12/2017, In: Statistical Methods in Medical Research. 26, 6, p. 2633-2648 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Comparing sampling methods for pharmacokinetic studies using model averaged derived parameters

    Barnett, H. Y., Geys, H., Jacobs, T. & Jaki, T., 30/11/2017, In: Statistics in Medicine. 36, 27, p. 4301-4315 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    Patterns of infant mortality in rural England and Wales, 1850-1910

    Atkinson, P. D., Francis, B. J., Gregory, I. N. & Porter, C., 1/11/2017, In: Economic History Review. 70, 4, p. 1268-1290 23 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    Correcting the standard errors of two-stage residual inclusion estimators for Mendelian randomization studies

    Palmer, T. M., Holmes, M. V., Keating, B. J. & Sheehan, N. A., 1/11/2017, In: American Journal of Epidemiology. 186, 9, p. 1104-1114 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Non-parametric maximum likelihood estimation of interval-censored failure time data subject to misclassification

    Titman, A. C., 11/2017, In: Statistics and Computing. 27, 6, p. 1585-1593 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Bayesian clinical trial designs: another option for trauma trials?

    UK-REBOA Trial Investigators, 10/2017, In: Journal of Trauma and Acute Care Surgery. 83, 4, p. 736-741 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Estimation in multi-arm two-stage trials with treatment selection and time-to-event endpoint

    Brueckner, M., Titman, A. C. & Jaki, T. F., 10/09/2017, In: Statistics in Medicine. 36, 20, p. 3137-3153 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    A Bayesian adaptive design for clinical trials in rare diseases

    Williamson, F., Jacko, P., Villar, S. S. & Jaki, T. F., 09/2017, In: Computational Statistics and Data Analysis. 113, p. 136-153 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Education and coronary heart disease: mendelian randomisation study

    Tillmann, T., Vaucher, J., Okbay, A., Pikhart, H., Peasey, A., Kubinova, R., Pajak, A., Tamosiunas, A., Malyutina, S., Hartwig, F. P., Fischer, K., Veronesi, G., Palmer, T., Bowden, J., Davey Smith, G., Bobak, M. & Holmes, M. V., 30/08/2017, In: BMJ. 358, 10 p., j3542.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Two-stage phase II oncology designs using short-term endpoints for early stopping

    Kunz, C., Wason, J. M. S. & Kieser, M., 1/08/2017, In: Statistical Methods in Medical Research. 26, 4, p. 1671-1683 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Sample size re-estimation in paired comparative diagnostic accuracy studies with a binary response

    McCray, G., Titman, A. C., Ghaneh, P. & Lancaster, G., 14/07/2017, In: BMC Medical Research Methodology. 17, 11 p., 102.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Cross-sensory correspondences: heaviness is dark and low-pitched

    Walker, P., Scallon, G. & Francis, B. J., 1/07/2017, In: Perception. 46, 7, p. 772-792 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Taller height as a risk factor for venous thromboembolism: a Mendelian randomization meta-analysis

    Roetker, N., Armasu, S. M., Pankow, J. S., Lutsey, P. L., Tang, W., Rosenberg, M. A., Palmer, T. M., MacLehose, R. F., Heckbert, S. R., Cushman, M., de Andrade, M. & Folsom, A. R., 07/2017, In: Journal of Thrombosis and Haemostasis. 15, 7, p. 1334-1343 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian randomization analysis

    Dale, C., Fatemifar, G., Palmer, T., White, J., Prieto-Merino, D., Zabaneh, D., Engmann, J. E. L., Shah, T., Wong, A., Warren, H. R., McLachlan, S., Trompet, S., Moldovan, M., Morris, R. W., Sofat, R., Kumari, M., Hyppönen, E., Jefferis, B. J., Gaunt, T. R., Ben-Shlomo, Y. & 23 others, Zhou, A., Gentry-Maharaj, A., Ryan, A., de Mutsert, R., Noordam, R., Caulfield, M. J., Jukema, J. W., Worrall, B. B., Munroe, P. B., Menon, U., Power, C., Kuh, D., Lawlor, D. A., Humphries, S. E., Mook-Kanamori, D. O., Davey Smith, G., Sattar, N., Kivimaki, M., Price, J. F., Dudbridge, F., Hingorani, A. D., Holmes, M. V. & Casas, J-P., 13/06/2017, In: Circulation. 135, 24, p. 2373-2388 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Generalization of Cramér-Rao and Bhattacharyya inequalities for the weighted covariance matrix

    Kelbert, M. & Mozgunov, P., 1/06/2017, In: Mathematical Communications. 22, 1, p. 25-40 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Statistical modelling of a terrorist network

    Aitkin, M., Vu, D. & Francis, B. J., 06/2017, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 180, 3, p. 751-768 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Spatial modelling of rural infant mortality and occupation in nineteenth-century Britain

    Atkinson, P. D., Francis, B. J., Gregory, I. N. & Porter, C., 26/04/2017, In: Demographic Research. 36, p. 1337-1360 24 p., 44.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    On the Use of Cauchy Prior Distributions for Bayesian Logistic Regression

    Ghosh, J., Li, Y. & Mitra, R., 7/03/2017, In: Bayesian Analysis. 13, 2, p. 359-383 25 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Gambling harm and crime careers

    May-Chahal, C. A., Humphreys, L. N., Clifton, A. K., Francis, B. J. & Reith, G., 1/03/2017, In: Journal of Gambling Studies. 33, 1, p. 65-84 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Computation of an exact confidence set for a maximum point of a univariate polynomial function in a given interval

    Zhou, S., Wan, F., Liu, W. & Bretz, F., 03/2017, In: Statistics and Probability Letters. 122, p. 157-161 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Factorial versus multi-arm multi-stage designs for clinical trials with multiple treatments

    Jaki, T. F. & Vasileiou, D., 20/02/2017, In: Statistics in Medicine. 36, 4, p. 563-580 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    Asymmetric inner wedge group sequential tests with applications to verifying whether effective drug concentrations are similar in adults and children

    Hampson, L. V., Fisch, R., Van, L. M. & Jaki, T. F., 10/02/2017, In: Statistics in Medicine. 36, 3, p. 426-441 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Bayesian survival analysis in clinical trials: what methods are used in practice?

    Brard, C., Le Teuff, G., Le Deley, M-C. & Hampson, L. V., 1/02/2017, In: Clinical Trials. 14, 1, p. 78-87 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Additive and synergistic interactions amongst Orius laevigatus (Heteroptera: Anthocoridae), entomopathogens and azadirachtin for controlling western flower thrips (Thysanoptera: Thripidae)

    Otieno, J. A., Pallmann, P. S. & Poehling, H-M., 02/2017, In: BioControl. 62, 1, p. 85-95 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Using genetic variation to explore the causal effect of maternal pregnancy adiposity on future offspring adiposity: a Mendelian randomisation study

    Richmond, R., Timpson, N. J., Felix, J., Palmer, T. M., Gaillard, R., McMahon, G., Davey Smith, G., Jaddoe, V. & Lawlor, D. A., 24/01/2017, In: PLoS Medicine. 14, 1, 24 p., e1002221.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    Optimal design for experiments with possibly incomplete observations

    Lee, K. M., Biedermann, S. & Mitra, R., 2017, In: Statistica Sinica. 26 p.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Confidence sets for optimal factor levels of a response surface

    Wan, F., Liu, W., Bretz, F. & Han, Y., 12/2016, In: Biometrics. 72, 4, p. 1285-1293 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Investigating the relationship between the diversity index and frequency of offending

    Francis, B. J. & Humphreys, L. N., 12/2016, In: Journal of Developmental and Life Course Criminology . 2, 4, p. 397-416 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    'Threshold crossing': a useful way to establish the counterfactual in clinical trials?

    Eichler, H-G., Bloechl-Daum, B., Bauer, P., Bretz, F., Brown, J., Hampson, L. V., Honig, P., Krams, M., Leufkens, H., Lim, R., Lumpkin, M., Murphy, M., Pignatti, F., Posch, M., Schneeweiss, S., Trusheim, M. & Koenig, F., 12/2016, In: Clinical Pharmacology & Therapeutics. 100, p. 699-712 13 p.

    Research output: Contribution to journalJournal articlepeer-review

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