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Professor David Allsop

Formerly at Lancaster University

  1. Published

    Modulation of β-amyloid production and fibrillisation

    Allsop, D., Twyman, L., Davies, Y., Moore, S., York, A., Swanson, L. & Soutar, I., 2000, In: Biochemical Society Symposia. 67, p. 1-14 14 p.

    Research output: Contribution to Journal/MagazineLiterature reviewpeer-review

  2. Published

    Monoclonal antibodies raised against a subsequence of senile plaque core protein react with plaque cores, plaque periphery and cerebrovascular amyloid in Alzheimer's disease

    Allsop, D., Landon, M., Kidd, M., Lowe, J. S., Reynolds, G. P. & Gardner, A., 1986, In: Neuroscience Letters. 68, 2, p. 252-6 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases: an immunohistochemical study using amyloid β-protein antibody

    Ikeda, S., Allsop, D. & Glenner, G. G., 1989, In: Laboratory Investigation. 60, 1, p. 113-122 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    Nanomechanical and nanothermal mapping of initial stages of amyloid fibres formation

    Kolosov, O., Tovee, P., Tinker-Mill, C. & Allsop, D., 15/09/2014, p. 29. 1 p.

    Research output: Contribution to conference - Without ISBN/ISSN Abstractpeer-review

  5. Published

    Nanoscale SPM characterisation of nacre aragonite plates and synthetic human amyloid fibres

    Grishin, I., Tinker, C., Allsop, D., Robson, A. & Kolosov, O., 2012, NSTI-Nanotech 2012. Santa Clara, USA: CRC PRESS-TAYLOR & FRANCIS GROUP, Vol. 1. p. 110-113 4 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  6. Published

    Neurofibrillary tangles in some cases of dementia pugilistica share antigens with amyloid β-protein of Alzheimer's disease

    Allsop, D., Haga, S., Bruton, C., Ishii, T. & Roberts, G. W., 02/1990, In: American Journal of Pathology. 136, 2, p. 255-260 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    New evidence that the Alzheimer β-amyloid peptide does not spontaneously form free radicals: An ESR study using a series of spin-traps.

    Turnbull, S., Tabner, B. J., El-Agnaf, O. M. A., Twyman, L. J. & Allsop, D., 15/05/2001, In: Free Radical Biology and Medicine. 30, 10, p. 1154-1162 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Oxidative Stress, Cytotoxic and Inflammatory Effects of Urban Ultrafine Road-Deposited Dust from the UK and Mexico in Human Epithelial Lung (Calu-3) Cells

    Hammond, J., Maher, B. A., Gonet, T., Bautista, F. & Allsop, D., 14/09/2022, In: Antioxidants. 11, 9, 18 p., 1814.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Parkinson disease: progress towards a molecular biomarker for Parkinson disease

    Foulds, P., Mann, D. M. A., Mitchell, J. D. & Allsop, D., 07/2010, In: Nature Reviews Neurology. 6, 7, p. 359-361 3 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Phosphorylated α-synuclein as a potential biomarker for Parkinson's disease (Editorial)

    Foulds, P., Mann, D. & Allsop, D., 2012, In: Expert Review of Molecular Diagnostics. 12, 2, p. 115-117 3 p.

    Research output: Contribution to Journal/MagazineEditorial

  11. Published

    Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease

    Foulds, P., Mitchell, J. D., Parker, A., Turner, R., Green, G., Diggle, P., Hasegawa, M., Taylor, M., Mann, D. & Allsop, D., 2011, In: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 25, 12, p. 4127-4137 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    Pick's disease is associated with mutations in the tau gene.

    Pickering-Brown, S., Baker, M., Yen, S-H., Liu, W-K., Hasegawa, M., Cairns, N., Lantos, P. L., Rossor, M., Iwatsubo, T., Davies, Y., Allsop, D., Furlong, R., Owen, F., Hardy, J., David Mann, D. & Hutton, M., 12/2000, In: Annals of Neurology. 48, 6, p. 589-867 279 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Plasma amyloid-β concentrations in Alzheimer's disease : an alternative hypothesis.

    Fullwood, N. J., Hayashi, Y. & Allsop, D., 12/2006, In: Lancet Neurology. 5, 12, p. 1000-1001 2 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Plasma neurofilament light chain: A potential prognostic biomarker of dementia in adult Down syndrome patients

    Shinomoto, M., Kasai, T., Tatebe, H., Kondo, M., Ohmichi, T., Morimoto, M., Chiyonobu, T., Terada, N., Allsop, D., Yokota, I., Mizuno, T. & Tokuda, T., 5/04/2019, In: PLoS ONE. 14, 4, 13 p., e0211575.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration

    Foulds, P., Davidson, Y., Mishra, M., Hobson, D. J., Humphreys, K. M., Taylor, M., Johnson, N., Weintraub, S., Akiyama, H., Arai, T., Hasegawa, M., Bigio, E. H., Benson, F. E., Allsop, D. & Mann, D. M. A., 2009, In: Acta Neuropathologica. 118, 5, p. 647-658 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies

    Foulds, P., Yokota, O., Thurston, A., Davidson, Y., Ahmed, Z., Holton, J., Thompson, J. C., Akiyama, H., Arai, T., Hasegawa, M., Gerhard, A., Allsop, D. & Mann, D. M. A., 01/2012, In: Neurobiology of Disease. 45, 1, p. 188-195 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Presenilins: in search of functionality

    Karran, E. H., Allsop, D., Christie, G., Davis, J., Gray, C., Mansfield, F. & Ward, R. V., 08/1998, In: Biochemical Society Transactions. 26, 3, p. 491-496 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 2001, In: Current Topics in Medicinal Chemistry. 1, p. 483-493 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    Protein aggregation, metals and oxidative stress in neurodegenerative diseases.

    Tabner, B. J., El-Agnaf, O. M. A., German, M. J., Fullwood, N. J. & Allsop, D., 11/2005, In: Biochemical Society Transactions. 33, 5, p. 1082-1086 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer’s disease and Down syndrome

    Tatebe, H., Kasai, T., Ohmichi, T., Kishi, Y., Kakeya, T., Waragai, M., Kondo, M., Allsop, D. & Tokuda, T., 4/09/2017, In: Molecular Neurodegeneration. 12, 63, 11 p., 63.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    Quantification of βA4 protein deposition in the medial temporal lobe: a comparison of Alzheimer's disease and senile dementia of the Lewy body type

    Gentleman, S. M., Williams, B., Royston, M. C., Jagoe, R., Clinton, J., Perry, R. H., Ince, P. G., Allsop, D., Polak, J. M. & Roberts, G. W., 3/08/1992, In: Neuroscience Letters. 142, 1, p. 9-12 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Quantitative differences in the deposition of βA4 protein in the sulci and gyri of frontal and temporal isocortex in Alzheimer's disease

    Gentleman, S. M., Allsop, D., Bruton, C. J., Jagoe, R., Polak, J. M. & Roberts, G. W., 17/02/1992, In: Neuroscience Letters. 136, 1, p. 27-30 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    Quinacrine acts as an antioxidant and reduces the toxicity of the prion peptide PrP106-126.

    Turnbull, S., Tabner, B. J., Brown, D. R. & Allsop, D., 15/09/2003, In: NeuroReport. 14, 13, p. 1743-1745 3 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Raman spectroscopy to diagnose Alzheimer's disease and dementia with Lewy bodies in blood

    Paraskevaidi, M., Morais, C., Halliwell, D., Mann, D., Allsop, D., Martin-Hirsch, P. & Martin, F. L., 2018, In: ACS Chemical Neuroscience. 9, 11, p. 2786–2794 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer’s Aβ peptide

    Gregori, M., Taylor, M. N., Salvati, E., Re, F., Mancini, S., Balducci, C., Forloni, G., Zambelli, V., Sesana, S., Michael, M., Michail, C., Kolosov, O. V., Tinker-Mill, C. L., Sherer, M., Harris, S., Fullwood, N. J., Masserini, M. & Allsop, D., 02/2017, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 2, p. 723-732 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  26. Published

    Secretory derivatives of Alzheimer amyloid precursor protein in cerebrospinal fluid and brain: only Kunitz-containing forms show amyloid immunoreactivity

    Allsop, D., Kennedy, H. E. & Kametani, F., 1993, Alzheimer's disease: advances in clinical and basic research. Corain, B., Iqbal, K., Nicolini, M., Winblad, B., Wisniewski, H. M. & Zatta, P. (eds.). Chichester: Wiley, p. 421-429 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  27. Published

    Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks β/A4 amyloid immunoreactivity

    Kametani, F., Tanaka, K., Ishii, T., Ikeda, S., Kennedy, H. E. & Allsop, D., 15/03/1993, In: Biochemical and Biophysical Research Communications. 191, 2, p. 392-398 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  28. Published

    Self-Assembly and Anti-Amyloid Cytotoxicity Activity of Amyloid beta Peptide Derivatives

    Castelletto, V., Ryumin, P., Cramer, R., Hamley, I., Taylor, M. N., Allsop, D., Reza, M., Ruokolainen, J., Arnold, T., Hermida-Merino, D., Garcia, C. I., Leal, M. C. & Castaño, E., 8/03/2017, In: Scientific Reports. 7, 12 p., 43637.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  29. Published

    Senile plaque amyloid

    Kidd, M., Allsop, D. & Landon, M., 1985, Modern approaches to the dementias, part 1: etiology and pathophysiology. Clifford Rose, F. (ed.). Basel: Karger, p. 114-126 13 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  30. Published

    Senile plaque amyloid, paired helical filaments, and cerebrovascular amyloid in Alzheimer's disease are all deposits of the same protein

    Kidd, M., Allsop, D. & Landon, M., 1985, In: Lancet. 1, 8423, p. 278

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  31. Published

    Soluble oligomers for the diagnosis of neurodegenerative diseases.

    El-Agnaf, O. M. A., Walsh, D. M. & Allsop, D., 08/2003, In: Lancet Neurology. 2, 8, p. 461-462 2 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  32. Published

    ß-Hairpin mimics containing a piperidine-pyrrolidine scaffold modulate the ß-amyloid aggregation process preserving the monomer species

    Pellegrino, S., Tonali, N., Erba, E., Kaffy, J., Taverna, M., Contini, A., Taylor, M. N., Allsop, D., Gelmi, M. L. & Ongeri, S., 1/02/2017, In: Chemical Science. 8, 2, p. 1295-1302 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  33. Published

    Studies on inhibition of β-amyloid formation in APP-751-transfected IMR-32 cells, and SPA4CT-transfected SHSY5Y cells

    Allsop, D., Christie, G., Gray, C., Holmes, S., Markwell, R., Owen, D., Smith, L., Wadsworth, H., Ward, R. V., Hartmann, T., Lichtenthaler, S. F., Evin, G., Fuller, S., Tanner, J., Masters, C. L., Beyreuther, K. & Roberts, G. W., 1997, Alzheimer's disease: biology, diagnosis and therapeutics. Iqbal, K., Winblad, B., Nishimura, T., Takeda, M. & Wisniewski, H. M. (eds.). New York: Wiley, p. 717-727 11 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  34. Published

    Studies on the binding and proteolytic cleavage of an Alzheimer amyloid synthetic peptide

    Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 1991, Frontiers of Alzheimer research. Ishii, T., Allsop, D. & Selkoe, D. J. (eds.). Amsterdam: Elsevier, p. 171-183 13 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  35. Published

    TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's Syndrome: association with age, hippocampal sclerosis and clinical phenotype

    Davidson, Y. S., Raby, S., Foulds, P., Robinson, A., Thompson, J. C., Sikkink, S., Yusuf, I., Amin, H., Duplessis, D., Troakes, C., Al-Sarraj, S., Sloan, C., Esiri, M. M., Prasher, V. P., Allsop, D., Neary, D., Pickering-Brown, S. M., Snowden, J. S. & Mann, D. M. A., 12/2011, In: Acta Neuropathologica. 122, 6, p. 703-713 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  36. Published

    TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration

    Foulds, P., McAuley, E., Gibbons, L., Davidson, Y., Pickering-Brown, S. M., Neary, D., Snowden, J. S., Allsop, D. & Mann, D. M. A., 2008, In: Acta Neuropathologica. 116, 2, p. 141-146 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  37. Published

    The amylin peptide implicated in type 2 diabetes stimulates copper-mediated carbonyl group and ascorbate radical formation

    Masad, A., Tabner, B. J., Mayes, J. & Allsop, D., 15/08/2011, In: Free Radical Biology and Medicine. 51, 4, p. 869-875 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  38. Published

    The biology and molecular neuropathology of β-amyloid protein.

    Howlett, D. R., Allsop, D. & Karran, E. H., 2001, Neurobiology of Alzheimer's disease . Dawbarn, D. & Allen, S. J. (eds.). 2nd ed. ed. Oxford: Oxford University Press, p. 75-102 28 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  39. Published

    The effect of a high non-permissive temperature on chloroplast development in barley

    Allsop, D., Atkinson, Y. E. & Bradbeer, J. W., 1981, Photosynthesis V: chloroplast development. Akoyunoglou, G. (ed.). Philadelphia: Balaban International Science Services, p. 787-795 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  40. Published

    The immunoreactive profile at the N-terminal region of Aβ1-39/40 but not Aβ1-42 changes with transition from monomer/dimer to further peptide aggregates

    Kametani, F., Tanaka, K., Tokuda, T. & Allsop, D., 12/12/1995, In: Brain Research. 703, 1-2, p. 237-241 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  41. Published

    The isolation and amino acid composition of senile plaque core protein

    Allsop, D., Landon, M. & Kidd, M., 1983, In: Experimental Brain Research. 259, 2, p. 348-52 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  42. Published

    The nomenclature of the cerebral amyloid fibril protein in Alzheimer's disease

    Allsop, D., 01/1990, In: Neurobiology of Aging. 11, 1, p. 63-64 2 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  43. Published

    The occult aftermath of boxing

    Roberts, G. W., Allsop, D. & Bruton, C., 05/1990, In: Journal of Neurology, Neurosurgery and Psychiatry. 53, 5, p. 373-378 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  44. Published

    The production of hydrogen peroxide during early-stage protein aggregation: a common pathological mechanism in different neurodegenerative diseases?

    Tabner, B., Turnbull, S., Fullwood, N. J., German, M. & Allsop, D., 08/2005, In: Biochemical Society Transactions. 33, 4, p. 548-550 3 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  45. Published

    Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation

    Tinker-Mill, C., Mayes, J., Allsop, D. & Kolosov, O., 2014, In: Scientific Reports. 4, 7 p., 4004.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  46. Published

    Untangled - peptide-based inhibitors of tau aggregation as a potential treatment for Alzheimer's disease

    Allsop, D., Aggidis, A., Fullwood, N. J., Taylor, M. N., Foulds, P., Vincent, S. & Dale, M., 2018, In: Journal of Prevention of Alzheimer's Disease. 5, Suppl 1, p. S15-S16 2 p.

    Research output: Contribution to Journal/MagazineMeeting abstract

  47. Published

    Utilization of a multiple antigenic peptide as a calibration standard in the BAN50 single antibody sandwich ELISA for Aß oligomers

    Kasai, T., Tokuda, T., Taylor, M., Nakagawa, M. & Allsop, D., 8/06/2012, In: Biochemical and Biophysical Research Communications. 422, 3, p. 375-380 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  48. Published

    Variability of β-amyloid protein deposited lesions in Down's syndrome brains

    Ikeda, S., Tokuda, T., Yanagisawa, N., Kametani, F., Ohshima, T. & Allsop, D., 1994, In: The Tohoku Journal of Experimental Medicine. 174, 3, p. 189-198 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  49. Published

    Variation in the concentration and regional distribution of magnetic nanoparticles in human brains, with and without Alzheimer’s disease, from the UK

    Hammond, J., Maher, B., Ahmed, I. & Allsop, D., 30/04/2021, In: Scientific Reports. 11, 13 p., 9363.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  50. Published

    α-Synuclein and the pathogenesis of Parkinson’s disease.

    Martin, F., Allsop, D., Williamson, S. J. M., Paleologou, K. E. & El-Agnaf, O. M. A., 2004, In: Protein and Peptide Letters. 11, 3, p. 229-237 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  51. Published

    α-synuclein implicated in Parkinson’s disease catalyses the formation of hydrogen peroxide in vitro.

    Turnbull, S., Tabner, B. J., Moore, S., Davies, Y., El-Agnaf, O. M. A. & Allsop, D., 15/05/2001, In: Free Radical Biology and Medicine. 30, 10, p. 1163-1170 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  52. Published

    α-Synuclein implicated in Parkinson’s disease is present in extracellular biological fluids, including human plasma.

    El-Agnaf, O. M. A., Salem, S. A., Paleologou, K. E., Cooper, L. J., Fullwood, N. J., Gibson, M. J., Curran, M. D., Court, J. A., Mann, D. M. A., Ikeda, S-I., Cookson, M. R., Hardy, J. & Allsop, D., 10/2003, In: FASEB Journal. 17, 13, p. 1945-1947 3 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  53. Published

    α-Synuclein interacts with lipoproteins in plasma

    Nouri Emamzadeh, F. & Allsop, D., 10/2017, In: Journal of Molecular Neuroscience . 63, 2, p. 165-172 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  54. Published

    β(A4)-amyloid protein and parkinsonian dementia complex of Guam

    Gentleman, S. M., Perl, D., Allsop, D., Clinton, J., Royston, M. C. & Roberts, G. W., 5/01/1991, In: Lancet. 337, 8732, p. 55-56 2 p.

    Research output: Contribution to Journal/MagazineLetterpeer-review

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