Phytochemical studies of plant extracts enclosed in chitosan microparticles and the effect of phytoformulations on skin condition

Walendziak, W., Rodríguez Villegas, N., Douglas, T. & Kozlowska, J., 24/04/2025, (Accepted/In press) In: European Polymer Journal.

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Physicochemical properties of freeze-dried bigel-based materials composed of sodium alginate/whey protein isolate hydrogel and ethylcellulose/sunflower oil oleogel

Walendziak, W., Douglas, T. & Kozlowska, J., 14/04/2025, In: Biomacromolecules. 26, 4, p. 2344-2355 12 p.

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Synthesis of pH-sensitive ternary hydrogel with synergetic antibacterial response for the release of ampicillin sodium

Andlib, H., Shafiq, M., Sabir, A., Jabeen, S. & Douglas, T., 28/02/2025, In: Journal of Drug Delivery Science and Technology. 104, 106462.

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Preliminary in-vitro assessment of whey protein isolate hydrogel with cannabidiol as a potential hydrophobic oral drug delivery system for colorectal cancer therapy

Baines, D., Wright, K. & Douglas, T., 24/11/2024, In: Polymers. 16, 23, 3273.

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Whey protein isolate as a substrate to design Calendula officinalis flower extract controlled-release materials for potential skin application

Stachowiak-Trojanowska, N., Prus-Walendziak, W., Douglas, T. & Kozlowska, J., 11/05/2024, In: International Journal of Molecular Sciences. 25, 10, 5325.

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Whey protein isolate: a versatile dairy-derived hydrogel for bone and vascular tissue engineering and antimicrobial applications

Douglas, T. E. L., 29/03/2024, In: Hemijska Industrija. 78, 1S, 11.

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Generation of pearl/Calcium phosphate composite particles and their integration into porous chitosan scaffolds for bone regeneration

Li, Z., Rehman, I. U., Shepherd, R. & Douglas, T., 29/02/2024, In: Journal of Functional Biomaterials. 15, 3, 20 p., 55.

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The enrichment of whey protein isolate hydrogels with Poly-γ-glutamic acid promotes the proliferation and osteogenic differentiation of pre-osteoblasts

Baines, D., Platania, V., Tavernaraki, N., Parati, M., Wright, K., Radecka, I., Chatzinikolaidou, M. & Douglas, T., 23/12/2023, In: Gels. 10, 1, 18.

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The Enrichment of Whey Protein Isolate Hydrogels with Poly-γ-Glutamic Acid Promotes the Proliferation and Osteogenic Differentiation of Preosteoblasts

Baines, D. K., Platania, V., Tavernaraki, N. N., Parati, M., Wright, K., Radecka, I., Chatzinikolaidou, M. & Douglas, T. E. L., 23/12/2023, In: Gels. 10, 1, p. 18

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Endothelialization of Whey Protein Isolate-Based Scaffolds for Tissue Regeneration

Genç, H., Friedrich, B., Alexiou, C., Pietryga, K., Cicha, I. & Douglas, T., 12/10/2023, In: Molecules. 28, 20, 7052.

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Whey protein isolate/calcium silicate hydrogels for bone tissue engineering applications – preliminary evaluation in vitro

Ivory-Cousins, T., Nurzynska, A., Klimek, K., Baines, D., Truszkiewicz, W., Palka, K. & Douglas, T., 29/09/2023, In: Materials. 16, 19, 6484.

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The effect of chitosan on physicochemical properties of whey protein isolate scaffolds for tissue engineering applications

Gawel, M., Domalik-Pyzik, P., Douglas, T., Reczyńska-Kolman, K., Pamula, E. & Pielichowska, K., 23/09/2023, In: Polymers. 15, 19, 3867.

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Designing of Gradient Scaffolds and their Applications in Tissue Regeneration

Pattnaik, A., Sanket, A. S., Pradhan, S., Sahoo, R., Das, S., Pany, S., Douglas, T., Dandela, R., Liu, Q., Rajadas, J., Pati, S., De Smedt, S., Braeckmans, K. & Samal, S. K., 31/05/2023, In: Biomaterials. 296, 34 p., 122078.

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Biosurfactants as foaming agents in calcium phosphate bone cements

Cichon, E., Czechowska, J., Krok-Borkowicz, M., Allinson, S., Stepien, K., Smith, A., Pamula, E., Douglas, T. & Zima, A., 28/02/2023, In: Biomaterials Advances. 145, 14 p., 213273.

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Could Curdlan/Whey Protein Isolate/Hydroxyapatite Biomaterials Be Considered as Promising Bone Scaffolds?—Fabrication, Characterization, and Evaluation of Cytocompatibility towards Osteoblast Cells In Vitro

Klimek, K., Palka, K., Truszkiewicz, W., Douglas, T., Nurzynska, A. & Ginalska, G., 16/10/2022, In: Cells. 11, 20, 19 p., 3251.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Newly crosslinked chitosan- and chitosan-pectin-based hydrogels with high antioxidant and potential anticancer activity

Dziadek, M., Dziadek, K., Salagierski, S., Drozdowska, M., Serafim, A., Stancu, I.-C., Szatkowski, P., Kopec, A., Rajzer, I., Douglas, T. & Cholewa-Kowalska, K., 15/08/2022, In: Carbohydrate Polymers. 290, 12 p., 119486.

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WPI Hydrogels with a Prolonged Drug-Release Profile for Antimicrobial Therapy

Plastun, V., Prikhozhdenko, E., Gusliakova, O., Raikova, S., Douglas, T., Sindeeva, O. & Mayorova, O., 4/06/2022, In: Pharmaceutics. 14, 6, 15 p., 1199.

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Biomimetic biphasic curdlan-based scaffold for osteochondral tissue engineering applications: Characterization and preliminary evaluation of mesenchymal stem cell response in vitro

Klimek, K., Benko, A., Vandrovcová, M., Travnickova, M., Douglas, T., Tarczynska, M., Broz, A., Gaweda, K., Ginalska, G. & Bacakova, L., 30/04/2022, In: Biomaterials Advances. 135, 19 p., 212724.

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The influence of Ca/Mg ratio on autogelation of hydrogel biomaterials with bioceramic compounds

Abalymov, A., Lengert, E., Van der Meeren, L., Saveleva, M., Ivanova, A., Douglas, T., Douglas, E. L., Skirtach, A. G., Volodkin, D. & Parakhonskiy, B. V., 28/02/2022, In: Materials Science and Engineering: C . 133, 10 p., 112632.

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Freeze-dried curdlan/whey protein isolate-based biomaterial as promising scaffold for matrix-associated autologous chondrocyte transplantation – A pilot in vitro study

Klimek, K., Tarczynska, M., Truszkiewicz, W., Gaweda, K., Douglas, T. & Ginalska, G., 14/01/2022, In: Cells. 11, 2, 16 p., e282.

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Complex Material and Surface Analysis of Anterolateral Distal Tibial Plate of 1.4441 Steel

Hlinka, J., Dostalova, K., Dedkova, K. P., Madeja, R., Frydrysek, K., Koutecky, J., Sova, P. & Douglas, T., 27/12/2021, In: Metals. 12, 1, 14 p., e60.

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Heparin Enriched-WPI Coating on Ti6Al4V Increases Hydrophilicity and Improves Proliferation and Differentiation of Human Bone Marrow Stromal Cells

Facchetti, D., Hempel, U., Martocq, L., Smith, A., Koptyug, A., Surmenev, R., Surmeneva, M. & Douglas, T., 23/12/2021, In: International Journal of Molecular Sciences. 23, 1, 12 p., e139.

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CIEKAWOŚĆ TO NAJWAŻNIEJSZY KLUCZ DO SUKCESU: Rozmowa z dr. Timothy Douglasem z Lancaster University o zamiłowaniu do zgłębiania wiedzy i trudnościach badacza w czasie pandemii

Douglas, T., 15/12/2021, In: Inżynieria Materiałowa (Materials Engineering). 4-5

Research output: Contribution to Journal/Magazine › Journal article

Functionalization of additive-manufactured Ti6Al4V scaffolds with poly(allylamine hydrochloride)/poly(styrene sulfonate) bilayer microcapsule system containing dexamethasone

Chudinova, E., Koptyug, A., Mukhortova, Y., Pryadko, A., Volkova, A., Ivanov, A., Plotnikov, E., Khan, Y., Epple, M., Sokolova, V., Prymak, O., Douglas, T., Surmenev, R. & Surmeneva, M., 15/11/2021, In: Materials Chemistry and Physics. 273, 14 p., 125099.

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Phloroglucinol-enhanced whey protein isolate hydrogels with antimicrobial activity for tissue engineering

Platania, V., Douglas, T., Zubko, M., Ward, D., Pietryga, K. & Chatzinikolaidou, M., 31/10/2021, In: Materials Science and Engineering: C . 129, 112412.

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Electron Beam-Treated Enzymatically Mineralized Gelatin Hydrogels for Bone Tissue Engineering

Riedel, S., Ward, D., Kudlackova, R., Mazur, K., Bačáková, L., Kerns, J., Allinson, S., Ashton, L., Koniezcny, R., Mayr, S. & Douglas, T., 8/10/2021, In: Journal of Functional Biomaterials. 12, 4, p. 1-17 17 p.

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Amine-Rich Coatings to Potentially Promote Cell Adhesion, Proliferation and Differentiation, and Reduce Microbial Colonization: Strategies for Generation and Characterization

Martocq, L. & Douglas, T., 18/08/2021, In: Coatings. 11, 8, 19 p., 983.

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Modification of heat-induced whey protein isolate hydrogel with highly bioactive glass particles results in promising biomaterial for bone tissue engineering

Dziadek, M., Charuza, K., Kudlackova, R., Aveyard, J., D'Sa, R., Serafim, A., Stancu, I.-C., Iovu, H., Kerns, J., Allinson, S., Dziadek, K., Szatkowski, P., Cholewa-Kowalska, K., Bacakova, L., Pamula, E. & Douglas, T., 31/07/2021, In: Materials and Design. 205, 14 p., 109749.

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Investigations on the impact of the introduction of the Aloe vera into the hydrogel matrix on cytotoxic and hydrophilic properties of these systems considered as potential wound dressings

Kudlacik-Kramarczyk, S., Drabczyk, A., Glab, M., Alves De Lima, D., Lin, H., Douglas, T., Kuciel, S., Zagorska, A. & Tyliszczak, B., 30/04/2021, In: Materials Science and Engineering: C . 123, 12 p., 111977.

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Composites Based on Hydroxyapatite and Whey Protein Isolate for Applications in Bone Regeneration

Slota, D., Glab, M., Tyliszczak, B., Douglas, T., Rudnicka, K., Miernik, K., Urbaniak, M., Rusek-Wala, P. & Sobczak-Kupiec, A., 29/04/2021, In: Materials. 14, 9, 2317.

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Synthesis and characterization of polymer-based coatings modified with bioactive ceramic and bovine serum albumin

Florkiewicz, W., Slota, D., Placek, A., Pluta, K., Tyliszczak, B., Douglas, T. & Sobczak-Kupiec, A., 30/03/2021, In: Journal of Functional Biomaterials. 12, 2, 16 p., 21.

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Surface functionalization of chitosan as a coating material for orthopaedic applications: A Comprehensive Review

Kumari, S., Tiyyagura, H. R., Beeran Pottathara, Y., Kumar Sadasivuni, K., Ponnamma, D., Douglas, T., Skirtach, A. & Mohan, M. K., 1/03/2021, In: Carbohydrate Polymers. 255, 16 p., 117487.

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pH-sensitive dairy-derived hydrogels with a prolonged drug release profile for cancer treatment

Mayorova, O., Jolly, B., Verkhovskii, R., Plastun, V., Sindeeva, O. & Douglas, T., 5/02/2021, In: Materials. 14, 4, 13 p.

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Phenolic-Enriched Collagen Fibrillar Coatings on Titanium Alloy to Promote Osteogenic Differentiation and Reduce Inflammation

Mieszkowska, A., Beaumont, H., Martocq, L., Koptyug, A., Surmeneva, M., Surmenev, R., Naderi, J., Douglas, T. & Gurzawska-Comis, K., 3/09/2020, In: International Journal of Molecular Sciences. 21, 17, 15 p., 6406.

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Dairy-inspired coatings for bone implants from whey protein isolate-derived self-assembled fibrils

Rabe, R., Hempel, U., Martocq, L., Keppler, J. K., Aveyard, J. & Douglas, T., 3/08/2020, In: International Journal of Molecular Sciences. 21, 15, 7 p., 5544.

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Marine-inspired enzymatic mineralization of dairy-derived whey protein isolate (WPI) hydrogels for bone tissue regeneration

Norris, K., Kocot, M., Tryba, A.-M., Chai, F., Talari, A., Ashton, L., Parakhonskiy, B., Samal, S. K., Blanchemain, N., Pamula, E. & Douglas, T., 2/06/2020, In: Marine Drugs . 18, 6, 13 p., 294.

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Enhancement of biomimetic enzymatic mineralization of gellan gum polysaccharide hydrogels by plant-derived gallotannins

Douglas, T., Keppler, J. K., Vandrovcova, M., Plnencer, M., Beranova, J., Feuereisen, M., Parakhonskiy, B. V., Svenskaya, Y., Atkin, V., Ivanova, A., Ricquier , P., Balcaen, L., Vanhaecke, F., Schieber, A., Bacakova, L. & Skirtach, A. G., 27/03/2020, In: International Journal of Molecular Sciences. 21, 7, 18 p., 2315.

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Novel naturally derived whey protein isolate and aragonite biocomposite hydrogels have potential for bone regeneration

Gupta, D., Kocot, M., Tryba, A.-M., Serafim, A., Stancu, I.-C., Jaegermann, Z., Pamula, E., Reilly, G. C. & Douglas, T., 1/03/2020, In: Materials and Design. 188, 11 p., 108408.

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Novel whey protein isolate-based highly porous scaffolds modified with therapeutic ion-releasing bioactive glasses

Dziadek, M., Douglas, T., Dziadek, K., Zagrajczuk, B., Serafim, A., Stancu, I.-C. & Cholewa-Kowalska, K., 15/02/2020, In: Materials Letters. 261, 5 p., 127115.

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Novel multicomponent organic-inorganic WPI/gelatin/CaP hydrogel composites for bone tissue engineering

Dziadek, M., Kudlackova, R., Zima, A., Slosarczyk, A., Ziabka, M., Jelen, P., Shkarina, S., Cecilia, A., Zuber, M., Surmeneva, M., Surmenev, R., Bačáková, L., Cholewa-Kowalska, K. & Douglas, T., 30/11/2019, In: Journal of Biomedical Materials Research Part A. 107, 11, p. 2479-2491 13 p.

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Phenolic plant extract enrichment of enzymatically mineralized hydrogels

Douglas, T., Lopez-Heredia, M., Pulczynska, A., Łapa, A., Pietryga, K., Schaubroeck, D., Santos, S., Pais, A., Brackman, G., De Schamphelaere, K., Samal, S. K., Keppler, J. K., Bauer, J., Chai, F., Blanchemain, N., Coenye, T., Pamula, E. & Skirtach, A. G., 1/10/2019, In: Engineering of Biomaterials (Inzyneria Biomaterialow). 22, 149, p. 2-9 8 p.

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The mineralization effect on chitosan hydrogel structure containing collagen and alkaline phosphatase

Skwarczynska, A. L., Binias, D., Maniukiewicz, W., Modrzejewska, Z. & Douglas, T. E. L., 5/07/2019, In: Journal of Molecular Structure. 1187, p. 86-97 12 p.

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Electrospun polycaprolactone membranes with Zn-doped bioglass for nasal tissues treatment

Rajzer, I., Dziadek, M., Kurowska, A., Cholewa-Kowalska, K., Ziabka, M., Menaszek, E. & Douglas, T., 1/07/2019, In: Journal of Materials Science: Materials in Medicine. 30, 11 p., 80.

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Whey protein complexes with green tea polyphenols: antimicrobial, osteoblast-stimulatory and antioxidant activities

Carson, M., Keppler, J. K., Brackman, G., Dawood, D., Vandrovcová, M., El-Sayed, K. F., Coenye, T., Clarke, S., Skirtach, A. G. & Douglas, T. E. L., 1/05/2019, In: cells tissues organs. 206, 1-2, p. 106-117 12 p.

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Hierarchy of hybrid materials – the place of inorganics-in-organics in it, their composition and applications

Saveleva, M., Eftekhari, K., Abalymov, A., Douglas, T. E. L., Volodkin, D., Parakhonskiy, B. V. & Skirtach, A. G., 4/04/2019, In: Frontiers in Chemistry. 7, 21 p., 179.

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Dissolved organic carbon and biodegradable dissolved organic carbon determination in river water of the Strug Basin

Piech, A., Trzyna, K., Skwarczynska-Wojsa, A. L. & Douglas, T., 31/03/2019, In: JOURNAL OF CIVIL ENGINEERING, ENVIRONMENT AND ARCHITECTURE. 36, 1, p. 27-35 9 p.

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Pectin-bioactive glass self-gelling, injectable composites with high antibacterial activity

Douglas, T. E. L., Dziadek, M., Schietse, J., Boone, M., Declercq, H., Coenye, T., Vanhoorne, V., Vervaet, C., Balcaen, L., Buchweitz, M., Vanhaecke, F., Van Assche, F., Cholewa-Kowalska, K. & Skirtach, A. G., 1/02/2019, In: Carbohydrate Polymers. 205, p. 427-436 10 p.

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Marine Polysaccharide-Collagen Coatings on Ti6Al4V Alloy Formed by Self-Assembly

Norris, K., Mishukova, O., Zykwinska, A., Colliec-Jouault, S., Sinquin, C., Koptioug , A., Cuenot, S., Kerns, J. G., Surmeneva, M., Surmenev, R. & Douglas, T. E. L., 19/01/2019, In: Micromachines. 10, 1, 10 p., 68.

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Effect of low-temperature plasma treatment of electrospun polycaprolactone fibrous scaffolds on calcium carbonate mineralisation

Ivanova, A., Syromotina, D., Shkarina, S., Shkarin, R., Cecilia, A., Weinhardt, V., Baumbach, T., Saveleva, M., Gorin, D., Douglas, T. E. L., Parakhonskiy, B., Skirtach, A. G., Cools, P., De Geyter, N., Morent, R., Oehr, C., Surmeneva, M. & Surmenev, R., 22/11/2018, In: RSC Advances. 8, 68, p. 39106-39114 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review