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Biomedical and Life Sciences

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  1. Releasing the cell cycle arrest with PROTACs to enhance DNA-damaging therapies

    Gadd, M. (Principal Investigator) & Allinson, S. (Co-Investigator)

    North West Cancer Research Fund

    1/10/20 → 31/12/24

    Project: Research

  2. MSI: High performance Wide spectral range Nanoprobe (HiWiN)

    Kolosov, O. (Principal Investigator), Jarvis, S. (Co-Investigator) & Fullwood, N. (Co-Investigator)

    Engineering and Physical Sciences Research Council

    8/02/21 → 7/09/24

    Project: Research

  3. Impact of Cannabis strain extracts on Inflammatory Bowel Disease models

    Wright, K. (Principal Investigator)

    MediCane Research and Development Ltd

    1/11/20 → 31/07/23

    Project: Research

  4. Mechanisms by which African tryanosomes sense and repsond to iron availability in the mammalian host

    Urbaniak, M. (Principal Investigator)

    BBSRC

    22/12/20 → 21/03/24

    Project: Research

  5. RECIRCULATE : GCRF: Driving eco-innovation in Africa:capacity-building for a safe circular water economy

    Paul, N. (Principal Investigator), Semple, K. (Co-Investigator), Martin, A. (Principal Investigator), Roy, M. (Principal Investigator), Pickup, R. (Principal Investigator), Dodd, I. (Principal Investigator), Rufino, M. (Principal Investigator), Larty, J. (Principal Investigator) & Jack, S. (Principal Investigator)

    1/10/17 → 31/12/21

    Project: Research

  6. Investigation of the impact of a novel Tau aggregation inhibitor peptide (RI-AG03) in a Drosophila model of Tauopathy

    Aggidis, A. (Principal Investigator)

    Alzheimer’s Research UK

    1/09/20 → 30/11/20

    Project: Research

  7. Development of CRISPR/Cas9 base Novel Poultry Vaccines against Endemic Viruses (PhD student: Julianne Vilela)

    Munir, M. (Principal Investigator)

    The British Council

    1/02/20 → 31/03/24

    Project: Research

  8. WASHable: Participatory design and community engagement Network on WASH in Lusophone and Francophone African Countries

    Pickup, R. (Co-Investigator)

    AHRC

    15/01/20 → 31/03/22

    Project: Research

  9. Peptide inhibitors of tau aggregation as a potential treatment for Alzheimer’s disease

    Allsop, D. (Principal Investigator), Fullwood, N. (Co-Investigator) & Fullwood, N. (Principal Investigator)

    Alzheimer’s Society

    1/02/20 → 31/10/22

    Project: Research

  10. Using the Asgard archaea to trace the natural history of protein homeostasis

    Robinson, N. (Principal Investigator)

    The Leverhulme Trust

    1/11/20 → 22/04/26

    Project: Research

  11. Dual morbidities in the developing world: The effect of obesity on susceptibility to nematode infection

    Worthington, J. (Principal Investigator)

    King Abdulaziz University

    1/12/19 → 30/11/21

    Project: Research

  12. Targeting perivascular innervation and vascular tone for improved clearance of ß-amyloid from the brain

    Hawkes, C. (Principal Investigator)

    Alzheimer’s Research UK

    1/10/19 → 31/08/20

    Project: Research

  13. A next generation Quiescence and Cell Cycle Indicator (QuCCi) for the refinement and reduction of animal usage in proliferation assays

    Mort, R. (Principal Investigator)

    National Centre for the Replacemnt Refinement and Reduction of Animals in Research

    7/01/20 → 6/07/23

    Project: Research

  14. NWCR Equipment grant: Spinning Disc Confocal Microscope for superfast multichannel live imaging

    Mort, R. (Principal Investigator) & Benedetto, A. (Principal Investigator)

    North West Cancer Research Fund

    1/10/19 → 31/03/20

    Project: Research

  15. ACTUATE : Accelerating the adoption of circular sanitation demonstration systems for improved health outcomes

    Pickup, R. (Principal Investigator)

    Engineering and Physical Sciences Research Council

    1/10/19 → 31/03/21

    Project: Research

  16. Investigating the Biological Mechanisms of Brain Ageing

    Broughton, S. (Principal Investigator)

    Sir John Fisher Foundation

    1/11/19 → 31/03/22

    Project: Research

  17. ACTUATE : Accelerating the adoption of circular sanitation demonstration systems for improved health outcomes

    Roy, M. (Co-Investigator), Martin, A. (Co-Investigator), Dada, L. (Co-Investigator), Tsekleves, E. (Co-Investigator), Semple, K. (Co-Investigator), Pickup, R. (Co-Investigator), Barker, P. (Principal Investigator) & Tsekleves, E. (Co-Investigator)

    Engineering and Physical Sciences Research Council

    1/10/19 → 31/12/21

    Project: Research

  18. Small molecule induced degradation of centrosome clustering proteins: development of a novel, cancer-specific therapeutic approach

    Fielding, A. (CoPI), Gadd, M. (CoPI) & Thomaz, A. (Research Associate)

    North West Cancer Research Fund

    27/01/20 → 31/10/23

    Project: Research

  19. How is the immune system alerted to persistent replication stress and DNA damage in keratinocytes during immunosurveillance against cutaneous squamous cell carcinoma?

    Jackson-Jones, L. (Principal Investigator) & Unterholzner, L. (Co-Investigator)

    North West Cancer Research Fund

    1/10/19 → 30/09/24

    Project: Research

  20. Integrated Multiomics of Host-bacteria Interactions during C. elegans Gut Infections

    Benedetto, A. (Principal Investigator)

    BBSRC

    31/01/20 → 30/04/25

    Project: Research

  21. Assess the anti-microbial properties of cold plasma

    Gaur, N. (Principal Investigator)

    Project: Research

  22. Monitor the effects of plasma delivered RONS to cells grown in 3-D scaffolds

    Gaur, N. (PhD Student)

    Project: Research

  23. How the orientation of the electric field from the plasma jet influences the delivery of reactive oxygen and nitrogen species into mammalian cells and tissues

    Gaur, N. (PhD Student)

    Project: Research

  24. Gamma H2AX as the parameter to assess effects of plasma jet on HaCaTs

    Gaur, N. (PhD Student)

    Project: Research

  25. Investigating the thermosensitivity of cancer cell division dynamics: toward cancer thermotherapies?

    Benedetto, A. (Principal Investigator), Mort, R. (Co-Investigator) & Fielding, A. (Co-Investigator)

    North West Cancer Research Fund

    1/07/19 → 30/09/20

    Project: Research

  26. Para-site-seeing

    Southern, J. (Principal Investigator) & Dillon, R. (Principal Investigator)

    1/08/18 → 31/08/19

    Project: Research

  27. The role of innate immunity in the response to radiation-induced DNA damage in human skin cells

    Unterholzner, L. (Principal Investigator) & Allinson, S. (Co-Investigator)

    North West Cancer Research Fund

    1/02/19 → 30/04/19

    Project: Research

  28. The gnatwork: building capacity for research on neglected tropical vectors

    Sedda, L. (Co-Investigator) & Dillon, R. (Principal Investigator)

    BBSRC

    1/03/19 → 29/02/20

    Project: Research

  29. University Hospitals of Morecambe Bay NHS Foundation Trust funded (Leese bequest) studentship - Modelling the role of the endothelium in cardiovascular physiology £61,000

    Roberts, S. (Principal Investigator), Owen-Lynch, J. (Co-Investigator) & Stefanovska, A. (Co-Investigator)

    1/09/10 → 31/08/13

    Project: Research

  30. Knowledge Transfer Partnership (KTP) award Micap plc. Developing novel encapsulation technology to protect and control the release of active ingredients from yeast. £135,323.

    Roberts, S. (Principal Investigator) & Price, C. (Principal Investigator)

    1/09/04 → 30/08/06

    Project: Research

  31. BBSRC project grant “Developing Pichia pastoris as a heterologous expression system for ion transporters £99, 169

    Roberts, S. (Principal Investigator) & Forde, B. (Principal Investigator)

    1/09/02 → 30/08/04

    Project: Research

  32. BBSRC Using modern molecular and cellular techniques to interpret plant responses to environmental change £1,053,816

    Roberts, S. (Co-Investigator)

    1/09/02 → …

    Project: Research

  33. 2001 BBSRC project grant Release of organic acid to the rhizosphere: a role for anion channels. £209, 216

    Roberts, S. (Principal Investigator), Roberts, M. (Principal Investigator) & Sanders, D. (Co-Investigator)

    Project: Research

  34. BBSRC Committee Studentship award for investigation of anion transport in Arabidopsis roots

    Roberts, S. (Principal Investigator)

    1/09/01 → 30/08/04

    Project: Research

  35. Lancaster University Small Grant Scheme Purchase of equipment for novel investigations of transporters in fungal membranes £6096

    Roberts, S. (Principal Investigator)

    3/05/02 → …

    Project: Research

  36. Wellcome Trust: The role of plasma membrane ion channels in fungal growth - potential targets for fungicides £311,656

    Roberts, S. (Principal Investigator)

    1/02/00 → 1/02/04

    Project: Research

  37. Effective Diagnostics and Novel Vaccine Strategies for the Control of Multiple Respiratory Viral Infections in Egyptian Poultry

    Munir, M. (Principal Investigator)

    British Council (London)

    1/04/18 → 28/02/21

    Project: Research

  38. Investigation of the immune response that occurs during mesothelioma

    Jackson-Jones, L. (Principal Investigator)

    Sir John Fisher Foundation

    1/08/19 → 30/01/23

    Project: Research

  39. Biology of Ageing - Sir John Fisher Foundation Studentship (Year 3)

    Broughton, S. (Principal Investigator)

    Sir John Fisher Foundation

    1/10/18 → 30/09/19

    Project: Research

  40. Innate immune recognition of intracellular DNA as 'stranger' and 'danger' signal

    Unterholzner, L. (Principal Investigator)

    European Commission

    1/01/15 → 31/12/18

    Project: Research

  41. Neuromodulation of death in Caenorhabditis elegans

    Benedetto, A. (Principal Investigator)

    The Wellcome Trust

    18/03/19 → 30/04/22

    Project: Research

  42. NWCR Equipment bid: Faxitron CellRad Irradiator

    Allinson, S. (Principal Investigator) & Unterholzner, L. (Co-Investigator)

    North West Cancer Research Fund

    1/10/18 → 31/03/19

    Project: Research

  43. The role of NSMCE2-dependent SUMO modification in the replication stress response

    Urbaniak, M. (Co-Investigator) & Taylor, E. (Principal Investigator)

    North West Cancer Research Fund

    1/05/19 → 31/07/23

    Project: Research

  44. MSI: A novel coating technology based upon polyatomic ions from plasma

    Pickup, R. (Co-Investigator), Evans, N. (Co-Investigator), Murphy, S. (Co-Investigator), Douglas, T. (Co-Investigator), Short, R. (Principal Investigator), Andrieux, F. (Co-Investigator) & Robinson, B. (Co-Investigator)

    Engineering and Physical Sciences Research Council

    1/02/19 → 30/08/22

    Project: Research

  45. Equipment: Cell microenvironment control platform for cancer biomedicine

    Benedetto, A. (Principal Investigator)

    North West Cancer Research Fund

    28/09/18 → 31/03/19

    Project: Research

  46. Keeping macrophages alive: sensing IgM for survival

    Jackson-Jones, L. (Principal Investigator)

    The Wellcome Trust

    1/04/19 → 1/07/22

    Project: Research

  47. Establishing Field Data-Driven Vaccine Platform for Newcastle Disease Virus in Poultry: Step Towards Poverty Alleviation & Food security in Kenya

    Munir, M. (Principal Investigator)

    British Council (London)

    1/05/18 → 30/04/19

    Project: Research

  48. Alzheimer's Research Project - Year 10

    Crawford, T. (Principal Investigator) & Parkin, E. (Co-Investigator)

    Sir John Fisher Foundation

    1/10/18 → 30/09/19

    Project: Research

  49. Alzheimer's Research Project - Years 11,12 & 13

    Crawford, T. (Principal Investigator), Stefanovska, A. (Co-Investigator), Benson, F. (Co-Investigator) & Fullwood, N. (Co-Investigator)

    Sir John Fisher Foundation

    1/10/19 → 30/09/22

    Project: Research

  50. Innate immune recognition of Herpes SImplex Virus in skin cells: Differences between neonatal and adult keratinocytes.

    Unterholzner, L. (Principal Investigator)

    1/08/14 → 28/02/16

    Project: Research

  51. How do keratinocytes sense the presence of intracellular DNA?

    Unterholzner, L. (Principal Investigator)

    1/02/14 → 31/08/15

    Project: Research

  52. IFNDNA: Elucidating the molecular mechanism of intracellular DNA recognition by the innate immune sensor IFI16

    Unterholzner, L. (Principal Investigator)

    1/02/13 → 31/07/18

    Project: Research

  53. NWCR Summer Studentships 2018 and 2019

    Allinson, S. (Principal Investigator), Rigby, R. (Co-Investigator), Copeland, N. (Co-Investigator), Taylor, E. (Co-Investigator), Lindsay, H. (Co-Investigator) & Wright, K. (Co-Investigator)

    North West Cancer Research Fund

    1/07/18 → 30/09/19

    Project: Research

  54. MSI: Feasibility of developing light emitting wound care dressing

    Hardy, J. (Principal Investigator), Wright, K. (Co-Investigator) & Mort, R. (Co-Investigator)

    Medilink North of England Ltd

    1/08/18 → 31/03/20

    Project: Research

  55. Low-cost Portable Molecular Diagnostic Platform for Rapid Detection of Poultry Infectious Pathogens

    Munir, M. (Principal Investigator)

    BBSRC

    1/04/18 → 31/03/21

    Project: Research

  56. Defying Dementia: Preliminary studies into peptide-based inhibitors of Tau aggregation

    Allsop, D. (Principal Investigator) & Fullwood, N. (Co-Investigator)

    Lancaster University

    1/07/18 → 31/12/18

    Project: Research

  57. Workshop on non-autonomous oscillatory systems and their applications in the life sciences

    Roberts, S. (Co-Investigator), Stefanovska, A. (Co-Investigator), Zmeev, D. (Co-Investigator), Luchinsky, D. (Co-Investigator) & McClintock, P. (Principal Investigator)

    Engineering and Physical Sciences Research Council

    1/06/18 → 30/11/19

    Project: Research

  58. Dissecting Essential Roles of Chicken Interferon Stimulated Genes in the Pathobiology of Poultry Viruses

    Munir, M. (Principal Investigator)

    BBSRC

    2/03/18 → 1/03/19

    Project: Research

  59. Emerging and Next Generation Vaccine Strategies Against Veterinary Viruses

    Munir, M. (Principal Investigator)

    British Council (London)

    1/04/18 → 28/02/19

    Project: Research

  60. Understanding the home as a source of infection of AMR bacteria carried by dust by exploring hygiene practices in different home environments in Ghana

    Pickup, R. (Co-Investigator) & Tsekleves, E. (Principal Investigator)

    AHRC

    22/01/18 → 20/04/21

    Project: Research

  61. Internal Project – FHM RCAD Contract Researcher Audit and Survey

    Brown, J. (Researcher), Pickup, R. (Principal Investigator), Morbey, H. (Principal Investigator) & Shaw, E. (Co-Investigator)

    1/09/16 → …

    Project: Other

  62. Novel genetic and biological control methods for an invasive insect pest.

    Sinkins, S. (Principal Investigator)

    1/10/10 → 1/09/14

    Project: Other

  63. PEC: Pickup external collaboration

    Pickup, R. (Principal Investigator)

    1/01/16 → 30/06/18

    Project: Other

  64. Identification of cyclin A-CDK2 substrates during the initation phase of DNA replication

    Copeland, N. (Principal Investigator)

    1/09/11 → 31/08/16

    Project: Other

  65. Patchworks: Catalyst Sprint Project

    Dillon, R. (Principal Investigator)

    1/03/12 → 31/10/12

    Project: Other

  66. Structure and Function of glycosaminoglycans

    Lauder, B. (Principal Investigator)

    1/01/01 → …

    Project: Other

  67. Bacterial Toxins

    Lauder, B. (Principal Investigator)

    1/01/01 → …

    Project: Other

  68. Characterisation of glycosaminoglycans

    Lauder, B. (Principal Investigator)

    1/01/01 → …

    Project: Other

  69. MSI: Synthesis and Characterisation of RAFT mediated gels and its application in diverse field

    Hardy, J. (Principal Investigator), Pickup, R. (Co-Investigator) & Hardy, J. (Principal Investigator)

    British Council, New Delhi

    3/09/18 → 2/01/19

    Project: Research

  70. Proximity to Discover: Industry Engagement for Impact

    Jarvis, S. (Co-Investigator), Wright, K. (Co-Investigator), Mort, R. (Co-Investigator), Hardy, J. (Co-Investigator), Robinson, B. (Co-Investigator), Ashton, L. (Co-Investigator), Kerns, J. (Co-Investigator), Rennie, A. (Co-Investigator), Cheneler, D. (Co-Investigator), Atkinson, P. (Principal Investigator), Allinson, S. (Co-Investigator), Hathaway, H. (Co-Investigator), Short, R. (Co-Investigator), Helal, S. (Co-Investigator), Ashmore, L. (Co-Investigator), Ni, Q. (Co-Investigator), Karnik, A. (Co-Investigator), Knight, J. (Co-Investigator), Taylor, B. (Co-Investigator), Lunn, J. (Co-Investigator), Lunn, J. (Co-Investigator) & Knight, J. (Co-Investigator)

    Medical Research Council

    31/03/18 → 30/11/19

    Project: Research

  71. RECIRCULATE : GCRF: Driving eco-innovation in Africa:capacity-building for a safe circular water economy

    Paul, N. (Principal Investigator), Semple, K. (Co-Investigator), Lockett, N. (Co-Investigator), Pickup, R. (Co-Investigator), Dodd, I. (Co-Investigator), Jack, S. (Co-Investigator), Roy, M. (Co-Investigator), Martin, A. (Co-Investigator), Rufino, M. (Co-Investigator), Paul, N. (Co-Investigator), Semple, K. (Principal Investigator) & Forson, C. (Co-Investigator)

    ESRC

    1/10/17 → 31/03/22

    Project: Research

  72. How does p53 link DNA damage to innate immunity?

    Unterholzner, L. (Principal Investigator)

    North West Cancer Research Fund

    1/01/18 → 31/05/21

    Project: Research

  73. Molecular analysis of Ap4A mediated regulation of DNA replication and genome stability

    Copeland, N. (Principal Investigator)

    North West Cancer Research Fund

    1/10/17 → 30/09/23

    Project: Research

  74. Smartwound-plasma

    Short, R. (Principal Investigator) & Allinson, S. (Co-Investigator)

    EPSRC

    1/12/17 → 31/01/21

    Project: Research

  75. Ionic Coulomb blockade oscillations and the physical origins of permeation, selectivity, and their mutation transformations in biological ion channels

    McClintock, P. (Principal Investigator), Luchinsky, D. (Co-Investigator), Roberts, S. (Co-Investigator), Stefanovska, A. (Co-Investigator), Kaufman, I. (Researcher) & Fedorenko, O. (Researcher)

    EPSRC

    1/04/15 → 30/09/18

    Project: Research

  76. Dynamic Phosphorylation in the Post-Transcriptional Regulation of the Trypanosoma Brucei Cell Cycle

    Urbaniak, M. (Principal Investigator)

    1/07/15 → 30/06/19

    Project: Research

  77. UHMBT Studentship: Cognitive Dysfunction and Early Dementia in Chronic Kidney Disease

    Simpson, J. (Principal Investigator), Allsop, D. (Co-Investigator) & Crawford, T. (Co-Investigator)

    1/10/14 → 30/09/15

    Project: Research

  78. Towards disease diagnosis through spectrochemical imagining of tissue architecture

    Kolosov, O. (Principal Investigator), Allsop, D. (Co-Investigator) & Martin, F. (Co-Investigator)

    EPSRC

    12/11/13 → 11/11/16

    Project: Research

  79. A Drosophila-Herpetomonas model as a blueprint to study Leishmania infection in phlebotomine sand flies

    Dillon, R. (Principal Investigator) & Shawcross, E. (Researcher)

    BBSRC

    1/10/12 → 31/01/16

    Project: Research

  80. Development of Bacteraemia and Toxin Detection Methods

    Lauder, B. (Principal Investigator), Lauder, B. (Principal Investigator), Lauder, B. (Principal Investigator) & Bishop, L. (Team Member)

    University Hospitals of Morecambe Bay NHS Foundation Trust

    3/09/12 → 30/08/13

    Project: Research

  81. FP7: ROOTOPOWER: Empowering root targeted strategies to minimize abiotic stress impacts on horticultural crops

    Dodd, I. (Principal Investigator), Binley, A. (Co-Investigator) & Pickup, R. (Co-Investigator)

    European Commission

    1/01/12 → 31/12/15

    Project: Research

  82. The Contribution of microbes to the life of phlebotomine sand Flies

    Dillon, R. (Principal Investigator)

    1/10/11 → 31/10/12

    Project: Research

  83. UHMMPT MSc: An investigation of the hypothesis that bacterial toxins may trigger sudden life threaten

    Lauder, B. (Principal Investigator), Lauder, B. (Principal Investigator), Lauder, B. (Principal Investigator), Bishop, L. (Team Member) & McConnell, T. (Research Associate)

    University Hospitals of Morecambe Bay NHS Foundation Trust

    1/09/11 → 31/08/12

    Project: Research

  84. Transmission biology of leishmaniasis in Ghana

    Bates, P. (Principal Investigator), Diggle, P. (Co-Investigator), Dillon, R. (Co-Investigator) & McKean, P. (Co-Investigator)

    The Royal Society

    1/10/11 → 30/09/15

    Project: Research

  85. Dynamics of cardiovascular ageing

    Stefanovska, A. (Principal Investigator), McClintock, P. (Co-Investigator) & Owen-Lynch, J. (Co-Investigator)

    ESRC

    1/10/09 → 31/03/12

    Project: Research

  86. Novel biomarkers and alzheimer's disease

    Crawford, T. (Principal Investigator) & Allsop, D. (Co-Investigator)

    The Fisher Foundation

    1/10/09 → 30/09/13

    Project: Research

  87. Regulation of DNA replication by diadenosine nucleotides after DNA damage

    Nigel Jones, D. (Principal Investigator), Copeland, N. (Co-Investigator) & Sandy McLennan, P. (Co-Investigator)

    1/10/13 → 30/09/16

    Project: Research

  88. Lost in Translation: Cross - disciplinary analysis of knowledge exchange and effectiveness in animal disease management

    Heathwaite, L. (Principal Investigator), Crowe, A. (Co-Investigator), Medd, W. (Co-Investigator), Mort, M. (Co-Investigator), Mort, M. (Co-Investigator), Wynne, B. (Co-Investigator), Pickup, R. (Co-Investigator) & Pickup, R. (Co-Investigator)

    ESRC

    1/07/08 → 30/11/11

    Project: Research

  89. Ciência sem Fronteiras: Brazil Science without Borders Programme; Special Visiting Researcher

    Dillon, R. (Principal Investigator) & Genta, F. (Project Manager)

    1/06/12 → 31/05/15

    Project: Research

  90. FEC code for PYA7886: Dynamics of cardiovascular ageing: FEC code for PYA7886: Dynamics of cardiovascular ageing

    Owen-Lynch, J. (Principal Investigator), McClintock, P. (Co-Investigator) & Stefanovska, A. (Co-Investigator)

    1/10/09 → …

    Project: Research

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