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Medical and Social Statistics

  1. 2022
  2. E-pub ahead of print

    An order restricted multi-arm multi-stage clinical trial design

    Serra, A., Mozgunov, P. & Jaki, T., 19/01/2022, (E-pub ahead of print) In: Statistics in Medicine. 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Statistical models for Mendelian randomization analysis using summary-level data

    Uche-Ikonne, O., 2022, Lancaster University. 141 p.

    Research output: ThesisDoctoral Thesis

  4. 2021
  5. Published

    Hoehn and Yahr Stage and Striatal Dat-SPECT Uptake Are Predictors of Parkinson’s Disease Motor Progression

    PASADENA Investigators & Prasinezumab Study Group, 13/12/2021, In: Frontiers in Neuroscience. 15, 10 p., 765765.

    Research output: Contribution to journalJournal articlepeer-review

  6. E-pub ahead of print

    Using biomarkers to allocate patients in a response-adaptive clinical trial

    Jackson, H., Bowen, S. & Jaki, T., 25/11/2021, (E-pub ahead of print) In: Communications in Statistics: Simulation and Computation.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study

    Khoo, S. H., Fitzgerald, R., Fletcher, T., Ewings, S., Jaki, T., Lyon, R., Downs, N., Walker, L., Tansley-Hancock, O., Greenhalf, W., Woods, C., Reynolds, H., Marwood, E., Mozgunov, P., Adams, E., Bullock, K., Holman, W., Bula, M. D., Gibney, J. L., Saunders, G. & 18 others, Corkhill, A., Hale, C., Thorne, K., Chiong, J., Condie, S., Pertinez, H., Painter, W., Wrixon, E., Johnson, L., Yeats, S., Mallard, K., Radford, M., Fines, K., Shaw, V., Owen, A., Lalloo, D. G., Jacobs, M. & Griffiths, G., 12/11/2021, In: Journal of Antimicrobial Chemotherapy. 76, 12, p. 3286-3295 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    A permutation test for assessing the presence of individual differences in treatment effects

    Chang, C., Jaki, T., Sadiq, M. S., Kuhlemeier, A., Feaster, D., Cole, N., Lamont, A., Oberski, D., Desai, Y. & Lee Van Horn, M., 1/11/2021, In: Statistical Methods in Medical Research. 30, 11, p. 2369-2381 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Forthcoming

    Comparing Data Collection Strategies via Input Uncertainty When Simulating Testing Policies Using Viral Load Profiles

    Parmar, D., Morgan, L., Titman, A., Sanchez, S. & Regnier, E., 18/06/2021, (Accepted/In press).

    Research output: Contribution to conference - Without ISBN/ISSN Conference paperpeer-review

  10. Published

    Optimizing subgroup selection in two-stage adaptive enrichment and umbrella designs

    Ballarini, N. M., Burnett, T., Jaki, T., Jennison, C., König, F. & Posch, M., 31/05/2021, In: Statistics in Medicine. 40, 12, p. 2939-2956 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Applying methods for personalized medicine to the treatment of alcohol use disorder

    Kuhlemeier, A., Desai, Y., Tonigan, A., Witkiewitz, K., Jaki, T., Hsiao, Y-Y., Chang, C. & Van Horn, M. L., 30/04/2021, In: Journal of Consulting and Clinical Psychology. 89, 4, p. 288-300 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Bridging across patient subgroups in phase I oncology trials that incorporate animal data

    Zheng, H., Hampson, L. V. & Jaki, T., 1/04/2021, In: Statistical Methods in Medical Research. 30, 4, p. 1057-1071 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Recurrent events modelling of haemophilia bleeding events

    Titman, A., Wolfsegger, M. J. & Jaki, T., 31/03/2021, In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 70, 2, p. 351-371 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    To Adjust or Not to Adjust? When a "Confounder" Is Only Measured After Exposure

    Groenwold, R. H. H., Palmer, T. M. & Tilling, K., 31/03/2021, In: Epidemiology. 32, 2, p. 194-201 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Software Application Profile: Bayesian estimation of inverse variance weighted and MR-Egger models for two-sample Mendelian randomization studies-mrbayes

    Uche-Ikonne, O., Dondelinger, F. & Palmer, T., 28/02/2021, In: International Journal of Epidemiology. 50, 1, p. 43-49 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Adaptive enrichment trials: What are the benefits?

    Burnett, T. & Jennison, C., 10/02/2021, In: Statistics in Medicine. 40, 3, p. 690-711 22 p.

    Research output: Contribution to journalJournal articlepeer-review

  17. 2020
  18. Published

    Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs

    Burnett, T., Mozgunov, P., Pallmann, P., Villar, S. S., Wheeler, G. M. & Jaki, T., 19/11/2020, In: BMC Medicine. 18, 1, 21 p., 352.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    An information-theoretic approach for selecting arms in clinical trials

    Mozgunov, P. & Jaki, T. F., 10/11/2020, In: Journal of the Royal Statistical Society: Series B (Statistical Methodology). 82, 5, p. 1223-1247 25 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. E-pub ahead of print

    Whitehead et al. Response to “Misunderstandings of Multiple Systems Estimation.”

    Whitehead, J., Jackson, J., Balch, A. & Francis, B., 6/11/2020, (E-pub ahead of print) In: Journal of Human Trafficking. 5 p.

    Research output: Contribution to journalComment/debatepeer-review

  21. Published

    Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

    Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D. H., Hedman, Å. K., Schork, A., Page, K., Zhernakova, D. V., Wu, Y., Peters, J., Eriksson, N., Bergen, S. E., Boutin, T. S., Bretherick, A. D., Enroth, S., Kalnapenkis, A., Gådin, J. R., Suur, B. E., Chen, Y., Matic, L. & 63 others, Gale, J. D., Lee, J., Zhang, W., Quazi, A., Ala-Korpela, M., Choi, S. H., Claringbould, A., Danesh, J., Davey Smith, G., de Masi, F., Elmståhl, S., Engström, G., Fauman, E., Fernandez, C., Franke, L., Franks, P. W., Giedraitis, V., Haley, C., Hamsten, A., Ingason, A., Johansson, Å., Joshi, P. K., Lind, L., Lindgren, C. M., Lubitz, S., Palmer, T., Macdonald-Dunlop, E., Magnusson, M., Melander, O., Michaelsson, K., Morris, A. P., Mägi, R., Nagle, M. W., Nilsson, P. M., Nilsson, J., Orho-Melander, M., Polasek, O., Prins, B., Pålsson, E., Qi, T., Sjögren, M., Sundström, J., Surendran, P., Võsa, U., Werge, T., Wernersson, R., Westra, H-J., Yang, J., Zhernakova, A., Ärnlöv, J., Fu, J., Smith, J. G., Esko, T., Hayward, C., Gyllensten, U., Landen, M., Siegbahn, A., Wilson, J. F., Wallentin, L., Butterworth, A. S., Holmes, M. V., Ingelsson, E. & Mälarstig, A., 16/10/2020, In: Nature Metabolism. 2, 10, p. 1135-1148 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Statistics and the “little grey cells”

    Jackson, J., 1/10/2020, In: Significance. 17, 5, p. 10-11 2 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    A Critical Review of Graphics for Subgroup Analyses in Clinical Trials

    Ballarini, N. M., Chiu, Y-D., Koenig, F., Posch, M. & Jaki, T., 1/09/2020, In: Pharmaceutical Statistics. 19, 5, p. 541-560 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Bias induced during the estimation of quality-adjusted life-years

    Welsh, A., Costain, D. & Titman, A., 08/2020. 5 p.

    Research output: Contribution to conference - Without ISBN/ISSN Conference paper

  25. Published

    Covid-19 deaths: How are gender, age and underlying health condition related?

    Jackson, J., 27/07/2020, In: Significance. 680.

    Research output: Contribution to journalJournal article

  26. Published

    Attitudes to immigration and human values – a repeated cross-sectional study in three European countries

    Hoti, V., 14/07/2020, Lancaster University. 237 p.

    Research output: ThesisDoctoral Thesis

  27. Published

    Discussion on the paper by Silverman (2020): James Jackson (Lancaster University)

    Jackson, J., 1/06/2020, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 183, 3

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Estimation of treatment effects following a sequential trial of multiple treatments

    Whitehead, J., Desai, Y. & Jaki, T., 20/05/2020, In: Statistics in Medicine. 39, 11, p. 1593-1609 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    A benchmark for dose finding studies with continuous outcomes

    Mozgunov, P., Jaki, T. F. & Paoletti, X., 1/04/2020, In: Biostatistics. 21, 2, p. 189–201 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    A quantitative framework to inform extrapolation decisions in children

    Wadsworth, I., Hampson, L. V., Jaki, T., Sills, G. J., Marson, A. G. & Appleton, R., 1/02/2020, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 183, 2, p. 515-534 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. E-pub ahead of print

    Dynamic inference for non-Markov transition probabilities under random right-censoring

    Dobler, D. & Titman, A. C., 14/01/2020, (E-pub ahead of print) In: Scandinavian Journal of Statistics. 47, 2, p. 572-586 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Confidentiality challenges in releasing longitudinally linked data

    Mitra, R., Blanchard, S., Dove, I., Tudor, C. & Spicer, K., 2020, In: Transactions on Data Privacy. 13, 2, p. 151-170 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published
  34. 2019
  35. Published

    A Review of the National Male Survivors Helpline and Online Service - Project Report

    Weare, S., Hulley, J. & Pattinson, B., 11/11/2019, Lancaster: Lancaster University. 40 p.

    Research output: Book/Report/ProceedingsCommissioned report

  36. Published

    A flexible design for advanced Phase I/II clinical trials with continuous efficacy endpoints

    Mozgunov, P. & Jaki, T., 1/11/2019, In: Biometrical Journal. 61, 6, p. 1477-1492 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Loss Functions in Restricted Parameter Spaces and Their Bayesian Applications

    Mozgunov, P., Jaki, T. F. & Gasparini, M., 3/10/2019, In: Journal of Applied Statistics. 46, 13, p. 2314-2337 24 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. E-pub ahead of print

    Bayesian estimation of IVW and MR-Egger models for two-sample Mendelian randomization studies

    Uche-Ikonne, O., Dondelinger, F. & Palmer, T., 21/09/2019, (E-pub ahead of print) https://doi.org/10.1101/19005868: medRxiv.

    Research output: Working paper

  39. Published

    A novel measure of drug benefit–risk assessment based on Scale Loss Score

    Saint-Hilary, G., Robert, V., Gasparini, M., Jaki, T. F. & Mozgunov, P., 1/09/2019, In: Statistical Methods in Medical Research. 28, 9, p. 2738-2753 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    ‘Cost’ calculations as a barrier to gaining information under the Freedom of Information Act 2000 from the Police in England and Wales

    Kingston, S. E., Elliott, A. & Thomas, T., 1/08/2019, In: Policing and Society: An International Journal of Research and Policy. 29, 7, p. 834-847 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    A Bayesian model to estimate the cutoff and the clinical utility of a biomarker assay

    Vradi, E., Jaki, T. F., Vonk, R. & Brannath, W., 1/08/2019, In: Statistical Methods in Medical Research. 28, 8, p. 2538-2556 19 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    The effects of sample size on the estimation of regression mixture models

    Jaki, T. F., Kim, M., Lamont, A. E., George, M., Feaster, D. & Van Horn, M. L., 1/04/2019, In: Educational and Psychological Measurement. 79, 2, p. 358-384 27 p.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Instrumental variable estimation in semi-parametric additive hazards models

    Brueckner, M., Titman, A. C. & Jaki, T. F., 1/03/2019, In: Biometrics. 75, 1, p. 110-120 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    The influence of temperature on nutrient supply and demand: host plant quality is temperature dependent

    Clissold, F. J., Woodman, J. D., Wilson, K. & Simpson, S. J., 1/03/2019, In: INTEGRATIVE AND COMPARATIVE BIOLOGY. 59, Suppl. 1, p. E39-E39 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  45. Published

    The interactive impact of temperature and nutrition on disease resistance

    Clissold, F. J., Woodman, J. D., Wilson, K. & Simpson, S. J., 1/03/2019, In: INTEGRATIVE AND COMPARATIVE BIOLOGY. 59, Suppl. 1, p. E39-E39 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  46. Published

    Quantifying the association between progression-free survival and overall survival in oncology trials using Kendall's tau.

    Weber, E. & Titman, A. C., 28/02/2019, In: Statistics in Medicine. 38, 5, p. 703-719 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    The R package MAMS for designing multi-arm multi-stage clinical trials

    Jaki, T. F., Pallmann, P. S. & Magirr, D., 31/01/2019, In: Journal of Statistical Software. 88, 4, 25 p.

    Research output: Contribution to journalJournal articlepeer-review

  48. E-pub ahead of print

    A robust Bayesian meta-analytic approach to incorporate animal data into phase I oncology trials

    Zheng, H., Hampson, L. V. & Wandel, S., 16/01/2019, (E-pub ahead of print) In: Statistical Methods in Medical Research. 17 p.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Bayesian adaptive methods to incorporate preclinical data into phase I clinical trials

    Zheng, H., 2019, Lancaster University. 176 p.

    Research output: ThesisDoctoral Thesis

  50. Published

    Investigating the association between socio-economic position and stillbirth in Brazil and the UK

    Jones, A., 2019, Lancaster University. 318 p.

    Research output: ThesisDoctoral Thesis

  51. 2018
  52. Published

    An alternative method to analyse the Biomarker-strategy design

    Kunz, C. U., Jaki, T. F. & Stallard, N., 30/12/2018, In: Statistics in Medicine. 37, 30, p. 4636-4651 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Design and estimation in clinical trials with subpopulation selection

    Chiu, Y-D., Koenig, F., Posch, M. & Jaki, T. F., 20/12/2018, In: Statistics in Medicine. 37, 29, p. 4335-4352 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    Data collection on trafficking in human beings in the EU: Final report

    Francis, B., Walby, S., Pattinson, B., Elliott, A., Hoti - Llabjani, V., Phoenix, J., Verrall, R. & Peelo, M., 4/12/2018, Luxembourg: European Commission. 272 p.

    Research output: Book/Report/ProceedingsCommissioned report

  55. E-pub ahead of print

    The role of the home environment in neurocognitive development of children living in extreme poverty and with frequent illnesses: a cross-sectional study

    Nampijja, M., Kizindo, R., Apule, B., Lule, S. A., Muhangi, L., Titman, A., Elliott, A., Alcock, K. J. & Lewis, C. N., 3/12/2018, (E-pub ahead of print) In: Wellcome Open Research. 3, 17 p., 152.

    Research output: Contribution to journalJournal articlepeer-review

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