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Medical and Social Statistics

  1. 2023
  2. Published

    Using biomarkers to allocate patients in a response-adaptive clinical trial

    Jackson, H., Bowen, S. & Jaki, T., 2/12/2023, In: Communications in Statistics: Simulation and Computation. 52, 12, p. 5946-5965 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Identifying prodromal symptoms at high specificity for Parkinson’s disease

    Jackson, H., Anzures-Cabrera, J., Simuni, T., Postuma, R. B., Marek, K. & Pagano, G., 22/09/2023, In: Frontiers in Aging Neuroscience. 15, 1232387.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. E-pub ahead of print

    A comparison of Bayesian information borrowing methods in basket trials and a novel proposal of modified exchangeability‐nonexchangeability method

    Daniells, L., Mozgunov, P., Bedding, A. & Jaki, T., 23/08/2023, (E-pub ahead of print) In: Statistics in Medicine.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    A Bayesian multi‐arm multi‐stage clinical trial design incorporating information about treatment ordering

    Serra, A., Mozgunov, P. & Jaki, T., 20/07/2023, In: Statistics in Medicine. 42, 16, p. 2841-2854 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    An alternative to traditional sample size determination for small patient populations

    Jackson, H. & Jaki, T., 3/07/2023, In: Statistics in Biopharmaceutical Research. 15, 3, p. 596-607 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. E-pub ahead of print

    A Spline Function Method for Modelling and Generating a Nonhomogeneous Poisson Process

    Morgan, L., Nelson, B., Titman, A. & Worthington, D., 19/06/2023, (E-pub ahead of print) In: Journal of Simulation. 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Point estimation for adaptive trial designs I: A methodological review

    Robertson, D. S., Choodari‐Oskooei, B., Dimairo, M., Flight, L., Pallmann, P. & Jaki, T., 30/01/2023, In: Statistics in Medicine. 42, 2, p. 122-145 24 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Input Uncertainty Quantification for Quantiles

    Parmar, D., Morgan, L., Titman, A., Sanchez, S. & Williams, R., 23/01/2023, 2022 Winter Simulation Conference (WSC). Feng, B., Pedrielli, G., Peng, Y., Shashaani, S., Song, E., Corlu, C. G., Lee, L. H., Chew, E. P., Roeder, T. & Lendermann, P. (eds.). IEEE, p. 97-108 12 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  10. Published

    Confidence Intervals for the Treatment Effects in Adaptive Enrichment Designs

    Zhu, J., 2023, Lancaster University. 118 p.

    Research output: ThesisDoctoral Thesis

  11. Published

    Rare Disease Trials: Beyond the Randomised Controlled Trial

    Jackson, H., 2023, Lancaster University. 237 p.

    Research output: ThesisDoctoral Thesis

  12. 2022
  13. Published

    Penalty shootouts: Are estimates on the spot?

    Jackson, J., 31/12/2022, In: Significance. 19, 6, p. 10-13 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Dose finding studies for therapies with late‐onset toxicities: A comparison study of designs

    Barnett, H., Boix, O., Kontos, D. & Jaki, T., 30/12/2022, In: Statistics in Medicine. 41, 30, p. 5767-5788 22 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Practical implementation of the partial ordering continual reassessment method in a Phase I combination‐schedule dose‐finding trial

    Mozgunov, P., Jaki, T., Gounaris, I., Goddemeier, T., Victor, A. & Grinberg, M., 30/12/2022, In: Stat. Med.. 41, 30, p. 5789-5809 21 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Using saturated count models for user-friendly synthesis of large confidential administrative databases

    Jackson, J., Mitra, R., Francis, B. & Dove, I., 31/10/2022, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 185, 4, p. 1613-1643 31 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Whitehead et al. Response to “Misunderstandings of Multiple Systems Estimation.”

    Whitehead, J., Jackson, J., Balch, A. & Francis, B., 31/10/2022, In: Journal of Human Trafficking. 8, 4, p. 469-473 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Bandit Procedures for Designing Patient-Centric Clinical Trials

    Villar, S. S. & Jacko, P., 21/09/2022, Springer Series in Supply Chain Management. Chen, X., Jasin, S. & Shi, C. (eds.). 1 ed. London: Springer Nature, p. 365-389 25 p. (Springer Series in Supply Chain Management; vol. 18).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  19. Published

    On integrating the number of synthetic data sets m into the a priori synthesis approach

    Jackson, J., Mitra, R., Francis, B. & Dove, I., 14/09/2022, Privacy in Statistical Databases: International Conference, PSD 2022, Paris, France, September 21–23, 2022, Proceedings. Domingo-Ferrer, J. & Laurent, M. (eds.). Cham: Springer, p. 205-219 15 p. (Lecture Notes in Computer Science).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  20. Published

    Estimating quality-adjusted life-years: Assessing the bias induced for a terminal decline quality of life model

    Welsh, A., Costain, D. & Titman, A., 18/07/2022, Proceedings of the 36th International Workshop on Statistical Modelling: July 18-22, 2022 - Trieste, Italy. Torelli, N., Bellio, R. & Muggeo, V. (eds.). EUT Edizioni Università di Trieste, Trieste 2022, p. 354-359 6 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  21. Published

    Using saturated models for data synthesis

    Jackson, J., Francis, B., Mitra, R. & Dove, I., 18/07/2022, Proceedings of the 36th International Workshop on Statistical Modelling: July 18-22, 2022 - Trieste, Italy. Torelli, N., Bellio, R. & Muggeo, V. (eds.). EUT Edizioni Università di Trieste, Trieste 2022, p. 205-210 6 p. 34

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  22. Published

    Baseline and peak cortisol response to the low dose short Synacthen test relates to indication for testing, age and sex

    Park, J., Titman, A., Lancaster, G., Selvarajah, B., Collingwood, C., Powell, D., Das, U., Dharmaraj, P., Didi, M., Senniappan, S. & Blair, J., 30/06/2022, In: Journal of the Endocrine Society. 6, 6, p. bvac043 bvac043.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    An order restricted multi-arm multi-stage clinical trial design

    Serra, A., Mozgunov, P. & Jaki, T., 30/04/2022, In: Statistics in Medicine. 41, 9, p. 1613-1626 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    General tests of the Markov property in multi-state models

    Titman, A. & Putter, H., 30/04/2022, In: Biostatistics. 23, 2, p. 380-396 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    In Honour of Murray Aitkin: Special Issue of <Statistical Modelling>

    Francis, B. (ed.) & Hinde, J. (ed.), 22/04/2022, In: Statistical Modelling. 22, 1-2, p. 1-145 145 p.

    Research output: Contribution to Journal/MagazineSpecial issuepeer-review

  26. Published

    Comparing Data Collection Strategies via Input Uncertainty When Simulating Testing Policies Using Viral Load Profiles

    Parmar, D., Morgan, L., Titman, A., Regnier, E. & Sanchez, S., 28/02/2022, WSC '21: Proceedings of the Winter Simulation Conference. IEEE Press, 12 p. 101

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  27. Published

    Statistical models for Mendelian randomization analysis using summary-level data

    Uche-Ikonne, O., 2022, Lancaster University. 141 p.

    Research output: ThesisDoctoral Thesis

  28. Published

    The use of saturated count models for synthesis of large confidential administrative databases

    Jackson, J., 2022, Lancaster University. 151 p.

    Research output: ThesisDoctoral Thesis

  29. 2021
  30. Published

    Hoehn and Yahr Stage and Striatal Dat-SPECT Uptake Are Predictors of Parkinson’s Disease Motor Progression

    PASADENA Investigators & Prasinezumab Study Group, 13/12/2021, In: Frontiers in Neuroscience. 15, 10 p., 765765.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  31. Published

    Incidence and risk factors of long COVID in the UK: a single-centre observational study

    Nune, A., Durkowski, V., Titman, A., Gupta, L., Hadzhiivanov, M., Ahmed, A., Musat, C. & Sapktoa, H., 9/12/2021, In: The Journal of the Royal College of Physicians of Edinburgh. 51, 4, p. 338-343 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  32. Published

    Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study

    Khoo, S. H., Fitzgerald, R., Fletcher, T., Ewings, S., Jaki, T., Lyon, R., Downs, N., Walker, L., Tansley-Hancock, O., Greenhalf, W., Woods, C., Reynolds, H., Marwood, E., Mozgunov, P., Adams, E., Bullock, K., Holman, W., Bula, M. D., Gibney, J. L., Saunders, G., & 18 othersCorkhill, A., Hale, C., Thorne, K., Chiong, J., Condie, S., Pertinez, H., Painter, W., Wrixon, E., Johnson, L., Yeats, S., Mallard, K., Radford, M., Fines, K., Shaw, V., Owen, A., Lalloo, D. G., Jacobs, M. & Griffiths, G., 12/11/2021, In: Journal of Antimicrobial Chemotherapy. 76, 12, p. 3286-3295 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  33. Published

    A permutation test for assessing the presence of individual differences in treatment effects

    Chang, C., Jaki, T., Sadiq, M. S., Kuhlemeier, A., Feaster, D., Cole, N., Lamont, A., Oberski, D., Desai, Y. & Lee Van Horn, M., 1/11/2021, In: Statistical Methods in Medical Research. 30, 11, p. 2369-2381 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  34. E-pub ahead of print

    Proposing a Core Outcome Set for Physical Activity and Exercise Interventions in People With Rare Neurological Conditions

    Ramdharry, G., Buscemi, V., Boaz, A., Dawes, H., Jaki, T., Jones, F., Marsden, J., Paul, L., Playle, R., Randell, E., Robling, M., Rochester, L. & Busse, M., 21/10/2021, (E-pub ahead of print) In: Frontiers in Rehabilitation Sciences. 2, 13 p., 705474.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  35. Published

    Optimizing subgroup selection in two-stage adaptive enrichment and umbrella designs

    Ballarini, N. M., Burnett, T., Jaki, T., Jennison, C., König, F. & Posch, M., 31/05/2021, In: Statistics in Medicine. 40, 12, p. 2939-2956 18 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  36. Published

    Applying methods for personalized medicine to the treatment of alcohol use disorder

    Kuhlemeier, A., Desai, Y., Tonigan, A., Witkiewitz, K., Jaki, T., Hsiao, Y-Y., Chang, C. & Van Horn, M. L., 30/04/2021, In: Journal of Consulting and Clinical Psychology. 89, 4, p. 288-300 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  37. Published

    Bridging across patient subgroups in phase I oncology trials that incorporate animal data

    Zheng, H., Hampson, L. V. & Jaki, T., 1/04/2021, In: Statistical Methods in Medical Research. 30, 4, p. 1057-1071 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  38. Published

    To Adjust or Not to Adjust? When a "Confounder" Is Only Measured After Exposure

    Groenwold, R. H. H., Palmer, T. M. & Tilling, K., 31/03/2021, In: Epidemiology. 32, 2, p. 194-201 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  39. Published

    Recurrent events modelling of haemophilia bleeding events

    Titman, A., Wolfsegger, M. J. & Jaki, T., 1/03/2021, In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 70, 2, p. 351-371 21 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  40. Published

    Software Application Profile: Bayesian estimation of inverse variance weighted and MR-Egger models for two-sample Mendelian randomization studies-mrbayes

    Uche-Ikonne, O., Dondelinger, F. & Palmer, T., 28/02/2021, In: International Journal of Epidemiology. 50, 1, p. 43-49 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  41. Published

    Adaptive enrichment trials: What are the benefits?

    Burnett, T. & Jennison, C., 10/02/2021, In: Statistics in Medicine. 40, 3, p. 690-711 22 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  42. 2020
  43. Published

    Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs

    Burnett, T., Mozgunov, P., Pallmann, P., Villar, S. S., Wheeler, G. M. & Jaki, T., 19/11/2020, In: BMC Medicine. 18, 1, 21 p., 352.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  44. Published

    An information-theoretic approach for selecting arms in clinical trials

    Mozgunov, P. & Jaki, T. F., 10/11/2020, In: Journal of the Royal Statistical Society: Series B (Statistical Methodology). 82, 5, p. 1223-1247 25 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  45. Published

    Salivary cortisol, cortisone and serum cortisol concentrations are related to age and body mass index in healthy children and young people

    Titman, A., Price, V., Hawcutt, D., Chesters, C., Ali, M., Cacace, G., Lancaster, G., Peak, M. & Blair, J. C., 31/10/2020, In: Clinical Endocrinology. 93, 5, p. 572-578 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  46. Published

    Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

    Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D. H., Hedman, Å. K., Schork, A., Page, K., Zhernakova, D. V., Wu, Y., Peters, J., Eriksson, N., Bergen, S. E., Boutin, T. S., Bretherick, A. D., Enroth, S., Kalnapenkis, A., Gådin, J. R., Suur, B. E., Chen, Y., Matic, L., & 63 othersGale, J. D., Lee, J., Zhang, W., Quazi, A., Ala-Korpela, M., Choi, S. H., Claringbould, A., Danesh, J., Davey Smith, G., de Masi, F., Elmståhl, S., Engström, G., Fauman, E., Fernandez, C., Franke, L., Franks, P. W., Giedraitis, V., Haley, C., Hamsten, A., Ingason, A., Johansson, Å., Joshi, P. K., Lind, L., Lindgren, C. M., Lubitz, S., Palmer, T., Macdonald-Dunlop, E., Magnusson, M., Melander, O., Michaelsson, K., Morris, A. P., Mägi, R., Nagle, M. W., Nilsson, P. M., Nilsson, J., Orho-Melander, M., Polasek, O., Prins, B., Pålsson, E., Qi, T., Sjögren, M., Sundström, J., Surendran, P., Võsa, U., Werge, T., Wernersson, R., Westra, H-J., Yang, J., Zhernakova, A., Ärnlöv, J., Fu, J., Smith, J. G., Esko, T., Hayward, C., Gyllensten, U., Landen, M., Siegbahn, A., Wilson, J. F., Wallentin, L., Butterworth, A. S., Holmes, M. V., Ingelsson, E. & Mälarstig, A., 16/10/2020, In: Nature Metabolism. 2, 10, p. 1135-1148 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  47. Published

    Statistics and the “little grey cells”

    Jackson, J., 1/10/2020, In: Significance. 17, 5, p. 10-11 2 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  48. Published

    A Critical Review of Graphics for Subgroup Analyses in Clinical Trials

    Ballarini, N. M., Chiu, Y-D., Koenig, F., Posch, M. & Jaki, T., 1/09/2020, In: Pharmaceutical Statistics. 19, 5, p. 541-560 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  49. Published

    Bias induced during the estimation of quality-adjusted life-years

    Welsh, A., 08/2020. 5 p.

    Research output: Contribution to conference - Without ISBN/ISSN Conference paper

  50. Published

    Covid-19 deaths: How are gender, age and underlying health condition related?

    Jackson, J., 27/07/2020, In: Significance. 680.

    Research output: Contribution to Journal/MagazineJournal article

  51. Published

    Bias induced during the estimation of quality-adjusted life-years

    Welsh, A., Costain, D. & Titman, A., 20/07/2020, Proceedings of the 35th International Workshop on Statistical Modelling. 5 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paper

  52. Published

    Attitudes to immigration and human values – a repeated cross-sectional study in three European countries

    Hoti, V., 14/07/2020, Lancaster University. 237 p.

    Research output: ThesisDoctoral Thesis

  53. Published

    Discussion on the paper by Silverman (2020): James Jackson (Lancaster University)

    Jackson, J., 1/06/2020, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 183, 3

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  54. Published

    Estimation of treatment effects following a sequential trial of multiple treatments

    Whitehead, J., Desai, Y. & Jaki, T., 20/05/2020, In: Statistics in Medicine. 39, 11, p. 1593-1609 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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