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Dr Mark McLaughlin

Lecturer

  1. 2022
  2. Forthcoming

    Aza-[4+2] Cycloadditions Employing Catalytically Derived N-Acyliminium Ions

    McLaughlin, M. & Owen, N., 11/10/2022, (Accepted/In press) In: Organic and Biomolecular Chemistry .

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Unified Approach to Diverse Fused Fragments via Catalytic Dehydrative Cyclization

    Basson, A., Halcovitch, N. & McLaughlin, M., 26/08/2022, In: Chemistry - A European Journal. 28, 48, 5 p., e202201107.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    Diastereoselective Access to Substituted Oxetanes via Hydrosilylation-Iodocyclisation of Homopropargylic Alcohols

    Roberts, D. & McLaughlin, M., 4/08/2022, In: Chemical Communications. 60, p. 8376-8379 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Cucurbitacins Elicit Anti-Platelet Activity via Perturbation of the Cytoskeleton and Integrin Function

    Kriek, N., Nock, S., Sage, T., Khalifa, B., Bye, A., Mitchell, J. L., Thomson, S., McLaughlin, M. G., Jones, S., Gibbins, J. M. & Unsworth, A., 31/07/2022, In: Thrombosis and Haemostasis. 122, 7, p. 1115-1129 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Strategic Applications of the β-Silicon Effect

    Roberts, D. & McLaughlin, M., 19/07/2022, In: Advanced Synthesis & Catalysis. 364, 14, p. 2307-2332 26 p.

    Research output: Contribution to Journal/MagazineReview articlepeer-review

  7. Published

    Recent advances in the catalytic generation of N-Acyliminium ions and subsequent applications

    Basson, A. & McLaughlin, M., 21/05/2022, In: Tetrahedron. 114, 27 p., 132764.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. 2021
  9. Published

    Aza-Peterson Olefinations: Rapid Synthesis of (E)-Alkenes

    Britten, T. K., Basson, A. J., Roberts, D. D. & McLaughlin, M. G., 31/10/2021, In: SYNTHESIS. 53, 19, p. 3535-3544 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Regioselective Synthesis of Multifunctional Allylic Amines; Access to Ambiphilic Aziridine Scaffolds

    Roberts, D. D. & McLaughlin, M. G., 4/06/2021, In: Organic Letters. 23, 11, p. 4463-4467 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Sustainable Access to 5‐Amino‐Oxazoles and Thiazoles via Calcium‐Catalyzed Elimination‐Cyclization with Isocyanides

    Basson, A. J. & McLaughlin, M. G., 9/04/2021, In: ChemSusChem. 14, 7, p. 1696-1699 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. 2020
  13. Published

    Synthesis of Functionalized Isoindolinones via Calcium Catalyzed Generation and Trapping of N-Acyliminium Ions

    Basson, A. J. & McLaughlin, M. G., 17/04/2020, In: The Journal of Organic Chemistry. 85, 8, p. 5615-5628 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Brønsted Acid Catalyzed Peterson Olefinations

    Britten, T. K. & McLaughlin, M. G., 17/01/2020, In: The Journal of Organic Chemistry. 85, 2, p. 301-305 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. 2019
  16. Published

    C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays

    Le Bihan, Y-V. & McLaughlin, M., 1/09/2019, In: European Journal of Medicinal Chemistry. 177, p. 316-337 22 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Functionalisation of isoindolinones via a calcium catalysed Hosomi–Sakurai allylation

    Basson, A. J. & McLaughlin, M. G., 21/07/2019, In: Chemical Communications. 55, 57, p. 8317-8320 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. 2018
  19. Published

    Mild, calcium catalysed Beckmann rearrangements

    Kiely-Collins, H. J., Sechi, I., Brennan, P. E. & McLaughlin, M. G., 18/10/2018, In: Chemical Communications. 54, 6, p. 654-657 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. 2016
  21. Published

    8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors

    Bavetsias, V. & McLaughlin, M., 25/02/2016, In: Journal of Medicinal Chemistry. 59, 4, p. 1388-1409 22 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. 2015
  23. Published

    An alkyne hydrosilylation-Hiyama coupling approach to highly functionalised 1,3-dienes

    McAdam, C. A., McLaughlin, M. G. & Cook, M. J., 1/05/2015, In: Organic Chemistry Frontiers. 2, 5, p. 510-514 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    MIDA–Vinylsilanes: Selective Cross-Couplings and Applications to the Synthesis of Functionalized Stilbenes

    McLaughlin, M., McAdam, C. A. & Cook, M. J., 2/01/2015, In: Organic Letters. 17, 1, p. 10-13 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. 2014
  26. Published

    Highly diastereoselective hydrosilylations of allylic alcohols

    McLaughlin, M. G. & Cook, M. J., 4/04/2014, In: Chemical Communications. 50, 26, p. 3501-3504 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  27. 2013
  28. Published

    NaH mediated isomerisation-allylation reaction of 1,3-substituted propenols

    Johnston, A. J. S., McLaughlin, M. G., Reid, J. P. & Cook, M. J., 28/11/2013, In: Organic and Biomolecular Chemistry. 11, 44, p. 7662-7666 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  29. Published

    Platinum catalysed hydrosilylation of propargylic alcohols

    McAdam, C. A., McLaughlin, M. G., Johnston, A. J. S., Chen, J., Walter, M. W. & Cook, M. J., 21/07/2013, In: Organic and Biomolecular Chemistry. 11, 27, p. 4488-4502 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  30. 2012
  31. Published

    The synthesis of N-heterocycles via copper/TEMPO catalysed aerobic oxidation of amino alcohols

    Flanagan, J. C. A., Dornan, L. M., McLaughlin, M. G., McCreanor, N. G., Cook, M. J. & Muldoon, M. J., 1/05/2012, In: Green Chemistry. 14, 5, p. 1281-1283 3 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  32. Published

    Domino Alkene-Isomerization–Claisen Rearrangement Strategy to Substituted Allylsilanes

    McLaughlin, M. & Cooke, M. J., 17/02/2012, In: The Journal of Organic Chemistry. 77, 4, p. 2058-2063 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  33. 2011
  34. Published

    PtCl2/XPhos : A highly efficient and readily available catalyst for the hydrosilylation of propargylic alcohols

    McLaughlin, M. G. & Cook, M. J., 2011, In: Chemical Communications. 47, 39, p. 11104-11106 3 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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