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Biomedical and Life Sciences

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  1. DSI: Towards understanding the RNA principles of innate immunity

    Gatsiou, A. (Principal Investigator)

    The Academy of Medical Sciences

    1/08/25 → 31/07/27

    Project: Research

  2. Uncovering the spatiotemporal neural dynamics of sleep-dependent memory processing

    Hannan, S. (Principal Investigator)

    The Academy of Medical Sciences

    1/08/25 → 31/07/27

    Project: Research

  3. Investigating neurogenetic determinants of organismal death processes in C. elegans.

    Benedetto, A. (Principal Investigator)

    11/06/25 → 5/08/25

    Project: Research

  4. FAME-AI: FAME-AI: Feedback And Marking using AI

    Clancy, D. (Principal Investigator)

    7/05/25 → 31/07/25

    Project: Research

  5. Development of advanced technologies to study pneumococcal infection in the human respiratory epithelium

    Weight, C. (Principal Investigator)

    The Royal Society

    31/03/25 → 30/03/27

    Project: Research

  6. Mechanisms of gut brain axis involvement in ectotherm thermotolerance: "how the gut brain axis helps animals weather the heat?"

    Benedetto, A. (Principal Investigator)

    BBSRC

    17/03/25 → 16/09/28

    Project: Research

  7. Investigating the role of ubiquitin ligase RNF169 in the DNA replication stress response

    Kotsantis, P. (Principal Investigator)

    The Royal Society

    1/03/25 → 31/05/26

    Project: Research

  8. Methods of Treating Fibrosis

    Hardy, J. (Principal Investigator), Copeland, N. (Co-Investigator) & Anwar, J. (Co-Investigator)

    Bolashak Center for International Programs JSC (Kazakhstan)

    1/03/25 → 31/12/25

    Project: Research

  9. Core Equipment 2024

    Robinson, B. (Co-Investigator), Harley, S. (Co-Investigator), Joyce, M. (Principal Investigator), Joyce, M. (Principal Investigator), Griffin, J. (Co-Investigator), Halcovitch, N. (Co-Investigator), Griffin, J. (Co-Investigator), Cheneler, D. (Co-Investigator), Robinson, B. (Co-Investigator), Fagan, D. (Co-Investigator) & Urbaniak, M. (Co-Investigator)

    Engineering and Physical Sciences Research Council

    1/01/25 → 30/06/26

    Project: Research

  10. Developing novel PROTACs for selective PDE4B degradation as a novel therapeutic in Alzheimers Disease

    Parkin, E. (Co-Investigator) & Dawson, N. (Principal Investigator)

    Alzheimer’s Research UK

    1/01/25 → 30/06/25

    Project: Research

  11. Evaluating Astrocyte Mechanisms of pH Regulation in Acid/Base Impairment in Alzheimer’s disease

    Theparambil, S. (Principal Investigator)

    1/01/25 → 31/12/25

    Project: Research

  12. Structure-Guided and Economical Platform for Effective Vaccines Development

    Munir, M. (Principal Investigator)

    The British Council

    1/01/25 → 31/12/26

    Project: Research

  13. NWB CASE DTP: Design and implementation of a passive trap for monitoring and control of Aedes aegypti and Culex pipiens: mosquitos of significant public health importance

    Hamilton, G. (Principal Investigator)

    Russell IPM

    2/12/24 → 1/12/28

    Project: Research

  14. Development of a rapid on-site diagnostic platform for detection of foodborne pathogens in fish and shellfish production

    Munir, M. (Principal Investigator)

    Innovate UK

    1/12/24 → 31/03/26

    Project: Research

  15. Development of Galleria mellonella as a replacement preclinical model for snakebite envenoming to reduce the need for murine models.

    Menzies, S. (Co-Investigator), Clare, R. (Principal Investigator) & Wakefield, J. (Co-Investigator)

    Medical Research Council

    1/12/24 → 30/11/27

    Project: Research

  16. Investigating astroglial bicarbonate transport in stroke-induced pH imbalance and injury in the brain

    Theparambil, S. (Principal Investigator) & Hawkes, C. (Co-Investigator)

    1/12/24 → 31/10/26

    Project: Research

  17. Neddylation underlying Cell Differentiation and Biology in Trypanosomes, evolutionarily distinct human pathogens.

    Rojas Martinez, F. (Principal Investigator)

    1/11/24 → 31/10/29

    Project: Research

  18. A new solution for an age-old problem: The pharmacological development of synergistic drug combinations for neglected tropical snakebite

    Hall, S. (Principal Investigator)

    Friends of Lancaster University in America INC

    1/10/24 → 30/09/25

    Project: Research

  19. Exploring the genetics of pigmentation in dairy cattle to build resilience to climate change induced heat stress

    Mort, R. (Principal Investigator)

    Livestock Improvement Corporation Limited

    1/10/24 → 30/09/28

    Project: Research

  20. Genome sequencing of 4 new isolates of Crithidia – an emerging parasite of humans

    Gatherer, D. (Principal Investigator) & Urbaniak, M. (Co-Investigator)

    1/10/24 → 30/09/25

    Project: Research

  21. Mechansisms of volatile organic compound detection for whipworm diagnosis

    Hamilton, G. (Co-Investigator) & Worthington, J. (Principal Investigator)

    1/10/24 → 30/09/26

    Project: Research

  22. Mechansisms of volatile organic compound detection for whipworm diagnosis (Additional Funding)

    Worthington, J. (Principal Investigator)

    1/10/24 → 30/09/26

    Project: Research

  23. p27-FucciCA - A next-generation Quiescence and Cell Cycle indicator for functional studies in mouse

    Mort, R. (Principal Investigator)

    1/10/24 → 30/09/25

    Project: Research

  24. The role of Gli similar transcription factors and the primary cilium in melanocyte development and melanoma phenotype switching

    Mort, R. (Principal Investigator) & Shih, B. (Co-Investigator)

    MRC Clinical Trials Unit

    1/10/24 → 31/03/28

    Project: Research

  25. The role of mETC and ATP synthase structures in Toxoplasma gondii infection

    Sheiner, L. (Principal Investigator), Maclean, A. (Co-Investigator), Worthington, J. (Co-Investigator) & Smith, D. (Co-Investigator)

    1/10/24 → 1/10/28

    Project: Research

  26. Volatile Organic Chemicals for Leishmania Detection

    Hamilton, G. (Principal Investigator), Worthington, J. (Co-Investigator) & Zhioua, E. (Co-Investigator)

    1/10/24 → 31/10/25

    Project: Research

  27. Spot the Difference: The Cellular and Clonal Basis of Dalmatian and Mouse Spots

    Mort, R. (Principal Investigator)

    1/09/24 → 29/02/28

    Project: Research

  28. Preparing for the next pandemic: creating a bovine antibody library for Disease X

    Menzies, S. (Principal Investigator)

    1/08/24 → …

    Project: Research

  29. High-resolution spatiotemporal mapping of brain and gut organismal death processes in C. elegans

    Benedetto, A. (Principal Investigator) & Shroff, H. (Principal Investigator)

    15/07/24 → 14/07/26

    Project: Research

  30. Investigating the Interplay of Organoselenides in Metal Homeostasis and the Gut-Brain Axis for General and Brain Health

    Benedetto, A. (Principal Investigator)

    1/07/24 → 1/07/27

    Project: Research

  31. North West Cancer Research Summer Studentships 2024

    Allinson, S. (Principal Investigator)

    1/07/24 → 30/09/24

    Project: Research

  32. Optimisation and pre-clinical development of a KIFC1-PROTAC as a triple-negative breast cancer therapeutic

    Fielding, A. (Principal Investigator)

    10/06/24 → 10/06/27

    Project: Research

  33. LU BBSRC 2024 International Partnership Fund

    Benedetto, A. (Principal Investigator)

    1/04/24 → 29/06/24

    Project: Research

  34. A comprehensive study of dysfunctional HDL to identify markers for cardiovascular disease status and risk

    Jackson-Jones, L. (Co-Investigator), Middleton, D. (Principal Investigator) & Allinson, S. (Co-Investigator)

    British Heart Foundation

    1/12/23 → 30/11/26

    Project: Research

  35. Designing bacterial gut communities to improve bee resilience to climate change

    Benedetto, A. (Principal Investigator)

    1/10/23 → 30/09/27

    Project: Research

  36. Epithelial cells as sentinels in innate immunity

    Unterholzner, L. (Principal Investigator)

    The Royal Society

    1/10/23 → 30/09/24

    Project: Research

  37. Investigation of IFI16 modulating molecules on Type I IFN inflammatory mediators following cytosolic DNA sensing or detection of nuclear DNA damage

    Unterholzner, L. (Principal Investigator)

    Kymera Therapeutics

    1/10/23 → 31/03/24

    Project: Research

  38. Regulation of DNA repair and the innate immune response to radio- and chemotherapy by the DNA sensors cGAS and IFI16.

    Unterholzner, L. (Principal Investigator)

    North West Cancer Research Fund

    1/10/23 → 30/09/26

    Project: Research

  39. Rapid and Smart Diagnostic System for Infectious Diseases

    Pickup, R. (Co-Investigator), Pickup, R. (Co-Investigator) & Munir, M. (Principal Investigator)

    1/09/23 → 31/08/25

    Project: Research

  40. Securing Better Health, Ageing, and Wellbeing

    Broughton, S. (Principal Investigator)

    BBSRC

    15/08/23 → 30/08/25

    Project: Research

  41. High-resolution spatiotemporal mapping of brain and gut organismal death processes in C. elegans.

    Benedetto, A. (Principal Investigator) & Shroff, H. (Principal Investigator)

    17/07/23 → 17/07/24

    Project: Research

  42. Summer Studentships Biomedical and Life Sciences Lancaster University

    Allinson, S. (Principal Investigator)

    North West Cancer Research Fund

    1/06/23 → 30/09/23

    Project: Research

  43. Targeting the gut-brain axis to improve animal resilience to a warming climate

    Benedetto, A. (Principal Investigator)

    17/04/23 → 31/07/23

    Project: Research

  44. REMIT: Reconstructing the In Vivo Evolution of Mesothelioma for Improved Therapy

    Jackson-Jones, L. (Principal Investigator)

    Cancer Research UK

    1/04/23 → 31/03/28

    Project: Research

  45. Making the Dust Fly: Creating a million plus conversations in Ghana on home cleaning and superbugs

    Tsekleves, E. (Principal Investigator), Pickup, R. (Co-Investigator) & Darby, A. (Research Associate)

    1/03/23 → 29/02/24

    Project: Research

  46. Volatile organic compound detection of intestinal whipworm infection

    Worthington, J. (Principal Investigator)

    King Abdulaziz University

    27/02/23 → 26/08/24

    Project: Research

  47. Mesothelioma Disease Evolution (CRUK Discovery Award supplement - REMIT)

    Jackson-Jones, L. (Principal Investigator)

    University of Cambridge

    1/02/23 → 31/01/24

    Project: Research

  48. EPSRC CORE Equipment 2022 - Lancaster University

    Heathwaite, L. (Principal Investigator), Heathwaite, L. (Principal Investigator) & Allinson, S. (Co-Investigator)

    Engineering and Physical Sciences Research Council

    3/01/23 → 3/07/24

    Project: Research

  49. Impact of paternal obesity on offspring brain structure and function; implications for Alzheimer's disease

    Hawkes, C. (Principal Investigator) & Dawson, N. (Co-Investigator)

    Alzheimer’s Research UK

    1/01/23 → 31/12/27

    Project: Research

  50. STING signalling as link between DNA damaging therapies and innate immunity in bladder cancer

    Unterholzner, L. (Principal Investigator)

    Cancer Research UK Manchester Institute

    1/12/22 → 30/11/25

    Project: Research

  51. Talent and Research Stabilisation Fund 2022 (Leonie Unterholzner)

    Unterholzner, L. (Principal Investigator)

    21/11/22 → 31/03/23

    Project: Research

  52. Understanding protein Ufmylation in Trypanosoma brucei

    Rojas Martinez, F. (Principal Investigator)

    The Royal Society

    17/10/22 → 16/10/23

    Project: Research

  53. WASHable II Impact Accelerator: Participatory design and community engagement Network on WASH in Lusophone and Francophone African Countries

    Tsekleves, E. (Principal Investigator), Pickup, R. (Co-Investigator) & Semple, K. (Co-Investigator)

    1/10/22 → 30/09/23

    Project: Research

  54. Horizon Europe: CLIMOS: Climate Monitoring and Decision Support Framework for Sand Fly-borne Diseases Detection and Mitigation with COst-benefit and Climate-policy MeasureS

    Hamilton, G. (Principal Investigator)

    UKRI

    1/09/22 → 31/05/26

    Project: Research

  55. Brazil-UK Partnership: New Bioactives for a Healthy Gut, targeting the gut microbiota

    Benedetto, A. (Principal Investigator) & Zarate Potes, A. (Co-Investigator)

    BBSRC

    1/06/22 → 31/05/26

    Project: Research

  56. Summer Studentships Biomedical and Life Sciences Lancaster University

    Allinson, S. (Principal Investigator)

    North West Cancer Research Fund

    1/06/22 → 30/09/22

    Project: Research

  57. Modalities for Understanding, Recording and Integrating Data Across Early life (MURIDAE)

    Dawson, N. (Principal Investigator)

    Medical Research Council

    1/04/22 → 31/03/27

    Project: Research

  58. Harnessing knowledge of lifespan biological, health, environmental and psychosocial mechanisms of cognitive frailty for integrated interventions

    Broughton, S. (Co-Investigator) & Holland, C. (Principal Investigator)

    BBSRC

    14/02/22 → 30/04/25

    Project: Research

  59. Harnessing knowledge of lifespan biological, health, environmental and psychosocial mechanisms of cognitive frailty for integrated interventions

    Broughton, S. (Co-Investigator) & Holland, C. (Principal Investigator)

    14/02/22 → 31/03/25

    Project: Research

  60. Characterisation of perivascular astrocyte heterogeneity in human brains

    Hawkes, C. (Principal Investigator)

    Alzheimer’s Research UK

    1/01/22 → 31/12/23

    Project: Research

  61. Re-purposing GLP-1 receptor agonists for use as ani-helminth therapy

    Worthington, J. (Principal Investigator)

    King Abdulaziz University

    1/01/22 → 31/12/23

    Project: Research

  62. Re-purposing GLP-1 receptor agonists for use as ani-helminth therapy

    Worthington, J. (Principal Investigator)

    Al Baha University

    1/01/22 → 31/12/23

    Project: Research

  63. Tropism, Immunity and Pathology in African sleeping sickness (HAT-TIP)

    Worthington, J. (Co-Investigator), Dawson, N. (Co-Investigator), Urbaniak, M. (Principal Investigator) & Jackson-Jones, L. (Co-Investigator)

    The Dowager Countess Eleanor Peel Trust

    1/01/22 → 30/09/22

    Project: Research

  64. Understanding the Mechanisms of antibiotic induced weight loss and subsequent impact on Immunity (Megan Dooley)

    Worthington, J. (Principal Investigator) & Rigby, R. (Co-Investigator)

    Defence Science and Technology Laboratory (DSTL)

    1/01/22 → 31/12/24

    Project: Research

  65. Heat shock signalling and response in African trypanosomes

    Urbaniak, M. (Principal Investigator)

    BBSRC

    1/12/21 → 30/11/25

    Project: Research

  66. Resolving the ‘dual-extraction bottleneck’ in transcriptomics for a deep understanding of host-microbe interactions

    Zarate Potes, A. (Principal Investigator)

    29/11/21 → 29/11/22

    Project: Research

  67. Inflammatory responses against viruses

    Munir, M. (Principal Investigator)

    Aeirtec Limited

    8/11/21 → 30/01/23

    Project: Research

  68. Building and optimisation of a microscope stage mounted stretch apparatus to investigate the role of physical forces in melanoblast behaviour

    Mort, R. (Principal Investigator) & Benedetto, A. (Co-Investigator)

    The Royal Society

    1/11/21 → 31/10/22

    Project: Research

  69. Development of New 3D Cell Model to Perform Cytotoxicity Assays Using a Panel of Common Cancer Therapeutics and Compare Expression and Localisation of CIZl Biomarker (Megan Fraser)

    Copeland, N. (Principal Investigator)

    AandA Biotech Limited

    11/10/21 → 10/10/22

    Project: Research

  70. An ethical investigation into healthcare sustainability (Dr. Joshua Parker)

    Allinson, S. (Co-Investigator), Wilkinson, S. (Co-Investigator) & Appleby, J. (Principal Investigator)

    The Wellcome Trust

    1/10/21 → 31/08/25

    Project: Research

  71. Local oxidised phospholipids within the pleural cavity: fuelling macrophage response during inflammation?

    Jackson-Jones, L. (Principal Investigator)

    Medical Research Council

    1/10/21 → 30/09/24

    Project: Research

  72. The generation and validation of novel molecular biology tools for the study of 'protective protein' combination therapies in Alzheimer's disease

    Parkin, E. (Principal Investigator) & Mort, R. (Co-Investigator)

    The Dowager Countess Eleanor Peel Trust

    1/10/21 → 30/09/23

    Project: Research

  73. The role of soluble APP fragments in Alzheimer's disease

    Parkin, E. (Principal Investigator), Dawson, N. (Principal Investigator) & Hawkes, C. (Principal Investigator)

    1/10/21 → 30/09/25

    Project: Research

  74. Defining the quality of good cholesterol from a combined structural and functional perspective

    Middleton, D. (Principal Investigator) & Allinson, S. (Co-Investigator)

    British Heart Foundation

    1/09/21 → 31/10/23

    Project: Research

  75. LIC has identified a structural variant of interest that is assumed to cause white spotting in the coats of bovine and wishes to undertake a model development project to demonstrate causality of this variant

    Mort, R. (Principal Investigator)

    Livestock Improvement Corporation Limited

    27/08/21 → 26/08/24

    Project: Research

  76. Nasal Cannabinoids in Covid-19/viral pathobiology

    Wright, K. (Principal Investigator) & Munir, M. (Co-Investigator)

    Gaea Science Ltd

    1/08/21 → 30/04/22

    Project: Research

  77. Functional Validation and Safety of Antimicrobial Properties of an Innovative Coating Material

    Munir, M. (Principal Investigator) & Pickup, R. (Co-Investigator)

    Viracoat Ltd

    1/07/21 → 30/06/25

    Project: Research

  78. NWCR Summer Studentship Renewal

    Allinson, S. (Principal Investigator), Parkin, E. (Co-Investigator), Copeland, N. (Co-Investigator), Fielding, A. (Co-Investigator), Rigby, R. (Co-Investigator) & Jackson-Jones, L. (Co-Investigator)

    North West Cancer Research Fund

    1/07/21 → 30/09/21

    Project: Research

  79. The local immune response in malignant pleural mesothelioma

    Jackson-Jones, L. (Principal Investigator)

    British Lung Foundation

    1/07/21 → 31/12/24

    Project: Research

  80. Cerebral glucose metabolism in the AppNL-G-F mouse model of Alzheimer’s disease

    Dawson, N. (Principal Investigator)

    Alzheimer’s Research UK

    9/06/21 → 8/06/22

    Project: Research

  81. Low-cost Portable Molecular Diagnostic Platform for Rapid Detection of Poultry Infectious Pathogens

    Munir, M. (Principal Investigator)

    1/04/21 → 30/09/21

    Project: Research

  82. Molecular analysis of Ap4A mediated regulation of DNA replication and genome stability

    Copeland, N. (Principal Investigator)

    1/04/21 → 30/09/23

    Project: Research

  83. Questioning Vaccination Discourse (Quo VaDis): A corpus-based study

    Semino, E. (Principal Investigator), Geyer, R. (Co-Investigator), Gatherer, D. (Co-Investigator), Brezina, V. (Co-Investigator) & Hardaker, C. (Co-Investigator)

    ESRC

    1/03/21 → 30/06/24

    Project: Research

  84. MSI: High performance Wide spectral range Nanoprobe (HiWiN)

    Kolosov, O. (Principal Investigator), Jarvis, S. (Co-Investigator) & Fullwood, N. (Co-Investigator)

    Engineering and Physical Sciences Research Council

    8/02/21 → 7/09/24

    Project: Research

  85. MSI: Plasma-activated antimicrobial hydrogel therapy (PAHT) for combatting infections in diabetic foot ulcers

    Jaki, T. (Co-Investigator), Mateus, C. (Co-Investigator), Hollingsworth, B. (Co-Investigator), Allinson, S. (Co-Investigator) & Short, R. (Principal Investigator)

    Engineering and Physical Sciences Research Council

    1/02/21 → 30/11/24

    Project: Research

  86. Evaluation of CoVID-19 Diagnostic Kits on Anonymized Human Samples

    Munir, M. (Principal Investigator)

    Katalyst Communications Ltd

    18/01/21 → 31/05/21

    Project: Research

  87. 3 Year Research PhD Studentship: Modulation of the innate immune responses by DNAzymes

    Unterholzner, L. (Principal Investigator)

    Defence Science and Technology Laboratory (DSTL)

    4/01/21 → 30/04/24

    Project: Research

  88. Mechanisms by which African tryanosomes sense and repsond to iron availability in the mammalian host

    Urbaniak, M. (Principal Investigator)

    BBSRC

    22/12/20 → 21/03/24

    Project: Research

  89. EPSRC Core Equipment 2020

    Jackson-Jones, L. (Co-Investigator), Nemeth, C. (Co-Investigator), O'Shea, P. (Principal Investigator) & Worthington, J. (Co-Investigator)

    Engineering and Physical Sciences Research Council

    14/11/20 → 13/05/22

    Project: Research

  90. Analysis of the role of CIZ1 in maintenance of genome stability and recovery form DNA replication stress

    Copeland, N. (Principal Investigator)

    North West Cancer Research Fund

    1/11/20 → 31/12/26

    Project: Research

  91. Impact of Cannabis strain extracts on Inflammatory Bowel Disease models

    Wright, K. (Principal Investigator)

    MediCane Research and Development Ltd

    1/11/20 → 31/07/23

    Project: Research

  92. Using the Asgard archaea to trace the natural history of protein homeostasis

    Robinson, N. (Principal Investigator)

    The Leverhulme Trust

    1/11/20 → 22/04/26

    Project: Research

  93. MSI: Electroactive Biomaterials for Drug Delivery and Tissue Engineering - PhD studentship - Hend Abdelrady Mohamed Abdelmohsen

    Hardy, J. (Principal Investigator) & Copeland, N. (Co-Investigator)

    British Council (London)

    1/10/20 → 30/09/24

    Project: Research

  94. MSI: Electroactive Biomaterials for Drug Delivery and Tissue Engineering - PhD studentship - Hend Abdelrady Mohamed Abdelmohsen

    Copeland, N. (Co-Investigator) & Hardy, J. (Principal Investigator)

    The Egyptian Bureau for Cultural and Educational Affairs

    1/10/20 → 30/09/24

    Project: Research

  95. Releasing the cell cycle arrest with PROTACs to enhance DNA-damaging therapies

    Gadd, M. (Principal Investigator) & Allinson, S. (Co-Investigator)

    North West Cancer Research Fund

    1/10/20 → 31/12/24

    Project: Research

  96. HiWiN: High performance Wide spectral range Nanoprobe

    Mikhaylovskiy, R. (Co-Investigator), Kolosov, O. (Principal Investigator), Jarvis, S. (Co-Investigator) & Fullwood, N. (Co-Investigator)

    1/09/20 → 31/01/23

    Project: Research

  97. Investigation of the impact of a novel Tau aggregation inhibitor peptide (RI-AG03) in a Drosophila model of Tauopathy

    Aggidis, A. (Principal Investigator)

    Alzheimer’s Research UK

    1/09/20 → 30/11/20

    Project: Research

  98. Development of CRISPR/Cas9 base Novel Poultry Vaccines against Endemic Viruses (PhD student: Julianne Vilela)

    Munir, M. (Principal Investigator)

    The British Council

    1/02/20 → 31/03/24

    Project: Research

  99. Peptide inhibitors of tau aggregation as a potential treatment for Alzheimer’s disease

    Allsop, D. (Principal Investigator), Fullwood, N. (Co-Investigator) & Fullwood, N. (Principal Investigator)

    Alzheimer’s Society

    1/02/20 → 31/10/22

    Project: Research

  100. Integrated Multiomics of Host-bacteria Interactions during C. elegans Gut Infections

    Benedetto, A. (Principal Investigator)

    BBSRC

    31/01/20 → 30/04/25

    Project: Research

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