Joint TITE-CRM: A Design for Dose Finding Studies for Therapies with Late-Onset Safety and Activity Outcomes

Barnett, H., Boix, O., Kontos, D. & Jaki, T., 17/04/2024, (E-pub ahead of print) In: Statistics in Biopharmaceutical Research. 29 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A Systematic Review of Methodologies Used in Models of the Treatment of Diabetes Mellitus

Antoniou, M., Mateus, C., Hollingsworth, B. & Titman, A., 1/01/2024, In: PharmacoEconomics. 42, 1, p. 19-40 22 p.

Research output: Contribution to Journal/Magazine › Review article › peer-review

Utilising high-dimensional data in randomised clinical trials: a review of methods and practice

Cherlin, S., Bigirumurame, T., Grayling, M., Nsengimana, J., Ouma, L., Santaolalla, A., Wan, F., Williamson, F. & Wason, J., 25/12/2023, (E-pub ahead of print) In: Research Methods in Medicine & Health Sciences.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Inference on extended-spectrum beta-lactamase Escherichia coli and Klebsiella pneumoniae data through SMC2

Rimella, L., Alderton, S., Sammarro, M., Rowlingson, B., Cocker, D., Feasey, N., Fearnhead, P. & Jewell, C., 30/11/2023, In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 72, 5, p. 1435–1451

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Estimation and Clustering of Directional Wave Spectra

Wu, Z., Euan, C., Crujeiras, R. M. & Sun, Y., 30/09/2023, In: Journal of Agricultural, Biological and Environmental Statistics. 28, 3, p. 502-525 24 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Consistent and fast inference in compartmental models of epidemics using Poisson Approximate Likelihoods

Whitehouse, M., Whiteley, N. & Rimella, L., 29/09/2023, In: Journal of the Royal Statistical Society: Series B (Statistical Methodology). 85, 4, p. 1173-1203 31 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Modelling the age-prevalence relationship in schistosomiasis: A secondary data analysis of school-aged-children in Mangochi District, Lake Malawi.

Reed, A., O'Ferrall, A., Kayuni, S., Baxter, H., Stanton, M., Stothard, J. R. & Jewell, C., 31/08/2023, In: Parasite epidemiology and control. 22, e00303.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Is hearing loss a risk factor for idiopathic Parkinson’s disease? An English Longitudinal Study of Ageing Analysis

Readman, M., Wan, F., Linkenauger, S., Crawford, T. & Plack, C., 12/08/2023, In: Brain Sciences. 13, 8, 1196.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

COVID-19 transmission dynamics and the impact of vaccination: modelling, analysis and simulations

Malinzi, J., Juma, V. O., Madubueze, C. E., Mwaonanji, J., Nkem, G. N., Mwakilama, E., Mupedza, T. V., Chiteri, V. N., Bakare, E. A., Moyo, I. L-Z., Campillo-Funollet, E., Nyabadza, F. & Madzvamuse, A., 31/07/2023, In: Royal Society Open Science. 10, 7, 24 p., 221656.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Investigating One Health risks for human colonisation with extended spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Malawian households: a longitudinal cohort study

Cocker, D., Chidziwisano, K., Mphasa, M., Mwapasa, T., Lewis, J. M., Rowlingson, B., Sammarro, M., Bakali, W., Salifu, C., Zuza, A., Charles, M., Mandula, T., Maiden, V., Amos, S., Jacob, S. T., Kajumbula, H., Mugisha, L., Musoke, D., Byrne, R., Edwards, T., & 7 othersLester, R., Elviss, N., Roberts, A. P., Singer, A. C., Jewell, C., Morse, T. & Feasey, N. A., 31/07/2023, In: The Lancet. Microbe. 4, 7, p. e534-e543 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Risk Factors, Temporal Dependence, and Seasonality of Human extended-spectrum β-lactamases-producing<i>Escherichia coli</i>and<i>Klebsiella pneumoniae</i>Colonization in Malawi: A Longitudinal Model-based Approach

Sammarro, M., Rowlingson, B., Cocker, D., Chidziwisano, K., Jacob, S. T., Kajumbula, H., Mugisha, L., Musoke, D., Lester, R., Morse, T., Feasey, N. & Jewell, C., 5/07/2023, In: Clinical Infectious Diseases. 77, 1, p. 1-8 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Backfilling cohorts in phase I dose-escalation studies

Barnett, H., Boix, O., Kontos, D. & Jaki, T., 30/06/2023, In: Clinical Trials. 20, 3, p. 261-268 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Contact patterns of UK home delivery drivers and their use of protective measures during the COVID-19 pandemic: a cross-sectional study

Bridgen, J. R. E., Wei, H., Whitfield, C., Han, Y., Hall, I., Jewell, C. P., van Tongeren, M. J. A. & Read, J. M., 30/06/2023, In: Occupational and Environmental Medicine. 80, 6, p. 333-338 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Individual and population level costs and health-related quality of life outcomes of third-generation cephalosporin resistant bloodstream infection in Blantyre, Malawi

Lester, R., Mango, J., Mallewa, J., Jewell, C. P., Lalloo, D. A., Feasey, N. A., Maheswaran, H. & Muniyandi, M. (ed.), 22/06/2023, In: PLOS Global Public Health. 3, 6, e0001589.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A Spline Function Method for Modelling and Generating a Nonhomogeneous Poisson Process

Morgan, L., Nelson, B., Titman, A. & Worthington, D., 19/06/2023, (E-pub ahead of print) In: Journal of Simulation. 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A hospital demand and capacity intervention approach for COVID-19

Van Yperen, J., Campillo-Funollet, E., Inkpen, R., Memon, A., Madzvamuse, A. & Ndeffo-Mbah, M. L. (ed.), 3/05/2023, In: PLoS One. 18, 5, 35 p., e0283350.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Air Pollution Exposure Among Adult Chronic Airway Disease Patients in the Gambia: A Pilot Case-control Study

Awokola, B. I., Mohammed, N., Okello, G., Johnson, O., Jatta, M. L., Susso, M., Gibba, A., Ndow, P., Awokola, E., Amusa, G. A., Jewell, C. P., Devereux, G., Mortimer, K. J. & Erhart, A., 1/05/2023, In: American Journal of Respiratory and Critical Care Medicine. 207, 1 p.

Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review

A novel statistical test for treatment differences in clinical trials using a response‐adaptive forward‐looking Gittins Index Rule

Barnett, H. Y., Villar, S. S., Geys, H. & Jaki, T., 31/03/2023, In: Biometrics. 79, 1, p. 86-97 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

An Updated Show of Hands

Barnett, H., Karapiperi, A. & Kastis, E., 6/03/2023, In: MSOR Connections. 21, 1, p. 18-22 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A dependent Bayesian Dirichlet process model for source apportionment of particle number size distribution

Baerenbold, O., Meis, M., Martínez‐Hernández, I., Euán, C., Burr, W. S., Tremper, A., Fuller, G., Pirani, M. & Blangiardo, M., 28/02/2023, In: Environmetrics. 34, 1, 18 p., e2763.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Effect of resistance to third-generation cephalosporins on morbidity and mortality from bloodstream infections in Blantyre, Malawi: a prospective cohort study

Lester, R., Musicha, P., Kawaza, K., Langton, J., Mango, J., Mangochi, H., Bakali, W., Pearse, O., Mallewa, J., Denis, B., Bilima, S., Gordon, S. B., Lalloo, D. G., Jewell, C. P. & Feasey, N. A., 31/12/2022, In: The Lancet. Microbe. 3, 12, p. e922-e930 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Dose finding studies for therapies with late‐onset toxicities: A comparison study of designs

Barnett, H., Boix, O., Kontos, D. & Jaki, T., 30/12/2022, In: Statistics in Medicine. 41, 30, p. 5767-5788 22 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Social mixing patterns in the UK following the relaxation of COVID-19 pandemic restrictions, July to August 2020: a cross-sectional online survey

Bridgen, J., Jewell, C. & Read, J., 13/12/2022, In: BMJ Open. 12, 12, 8 p., e059231.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Colonization dynamics of extended-spectrum beta-lactamase-producing Enterobacterales in the gut of Malawian adults

Lewis, J. M., Mphasa, M., Banda, R., Beale, M. A., Heinz, E., Mallewa, J., Jewell, C., Faragher, B., Thomson, N. R. & Feasey, N. A., 31/10/2022, In: Nature Microbiology. 7, 10, p. 1593-1604 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Hospitalisation and mortality risk of SARS-COV-2 variant omicron sub-lineage BA.2 compared to BA.1 in England

Webster, H. H., Nyberg, T., Sinnathamby, M. A., Aziz, N. A., Ferguson, N., Seghezzo, G., Blomquist, P. B., Bridgen, J., Chand, M., Groves, N., Myers, R., Hope, R., Ashano, E., Lopez-Bernal, J., De Angelis, D., Dabrera, G., Presanis, A. M. & Thelwall, S., 13/10/2022, In: Nature Communications. 13, 1, 6 p., 6053.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Reformulating the susceptible–infectious–removed model in terms of the number of detected cases: well-posedness of the observational model

Campillo-Funollet, E., Wragg, H., Yperen, J. V., Duong, D-L. & Madzvamuse, A., 3/10/2022, In: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 380, 2233, 15 p., 20210306.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Longitudinal Ambient PM 2.5 Measurement at Fifteen Locations in Eight Sub-Saharan African Countries Using Low-Cost Sensors

Awokola, B., Okello, G., Johnson, O., Dobson, R., Ouédraogo, A. R., Dibba, B., Ngahane, M., Ndukwu, C., Agunwa, C., Marangu, D., Lawin, H., Ogugua, I., Eze, J., Nwosu, N., Ofiaeli, O., Ubuane, P., Osman, R., Awokola, E., Erhart, A., Mortimer, K., & 3 othersJewell, C., Semple, S. & Suriano, D. (ed.), 29/09/2022, (E-pub ahead of print) In: Atmosphere. 13, 10, 16 p., 1593.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

EpiBeds: Data informed modelling of the COVID-19 hospital burden in England

Overton, C. E., Pellis, L., Stage, H. B., Scarabel, F., Burton, J., Fraser, C., Hall, I., House, T. A., Jewell, C., Nurtay, A., Pagani, F., Lythgoe, K. A. & Struchiner, C. J. (ed.), 6/09/2022, In: PLoS Computational Biology. 18, 9, 20 p., e1010406.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Recovery beyond clinical improvement - Recovery outcomes measured for people with bipolar disorder between 1980 and 2020

Mezes, B., Lobban, F., Costain, D., Hillier, L., Longson, D., Varese, F. & Jones, S. H., 15/07/2022, In: Journal of Affective Disorders. 309, p. 375-392 18 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Baseline and peak cortisol response to the low dose short Synacthen test relates to indication for testing, age and sex

Park, J., Titman, A., Lancaster, G., Selvarajah, B., Collingwood, C., Powell, D., Das, U., Dharmaraj, P., Didi, M., Senniappan, S. & Blair, J., 30/06/2022, In: Journal of the Endocrine Society. 6, 6, p. bvac043 bvac043.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Impact of intensified control on visceral leishmaniasis in a highly-endemic district of Bihar, India: an interrupted time series analysis

Kumar, V., Siddiqui, N. A., Pollington, T. M., Mandal, R., Das, S., Kesari, S., Das, V. R., Pandey, K., Hollingsworth, T. D., Chapman, L. A. C. & Das, P., 30/06/2022, In: Epidemics. 39, 8 p., 100562.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Statistical analysis of multi‐day solar irradiance using a threshold time series model

Euán, C., Sun, Y. & Reich, B. J., 31/05/2022, In: Environmetrics. 33, 3, e2716.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Measuring Air Quality for Advocacy in Africa (MA3): Ambient PM_2.5 Concentrations Over One-Year in 15 Locations in Eight Sub-Saharan African Countries Using Low-Cost Sensors

Awokola, B. I., Okello, G., Dobson, R., Amusa, G. A., Johnson, O., Erhart, A., Mortimer, K., Jewell, C., Semple, S. & MA3 Study Group, 2/05/2022, In: American Journal of Respiratory and Critical Care Medicine. 205, 2 p., A5170.

Research output: Contribution to Journal/Magazine › Conference article › peer-review

General tests of the Markov property in multi-state models

Titman, A. & Putter, H., 30/04/2022, In: Biostatistics. 23, 2, p. 380-396 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Influence of sex, season and environmental air quality on experimental human pneumococcal carriage acquisition: a retrospective cohort analysis

Cheliotis, K. S., Jewell, C. P., Solórzano, C., Urban, B., Collins, A. M., Mitsi, E., Pojar, S., Nikolaou, E., German, E. L., Reiné, J., Gordon, S. B., Jochems, S. P., Rylance, J. & Ferreira, D. M., 11/04/2022, In: ERJ open research. 8, 2, 10 p., 00586-2021.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021

Blomquist, P. B., Bridgen, J., Bray, N., O’Connell, A. M., West, D., Groves, N., Gallagher, E., Utsi, L., Jarvis, C. I., Hardstaff, J. L., Byers, C., Metelmann, S., Simons, D., Zaidi, A., Twohig, K. A., Savagar, B., Løchen, A., Wrenn, K., Saavedra-Campos, M., Abedin, Z., & 5 othersFlorence, I., Cleary, P., Elson, R., Vivancos, R. & Lake, I. R., 17/03/2022, In: Eurosurveillance. 27, 11, 5 p., 2200143.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Chronic obstructive pulmonary disease in sub-Saharan Africa

Awokola, B. I., Amusa, G. A., Jewell, C. P., Okello, G., Stobrink, M., Finney, L. J., Mohammed, N., Erhart, A. & Mortimer, K. J., 1/03/2022, In: International Journal of Tuberculosis and Lung Disease. 26, 3, p. 232-242 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Risk factor targeting for vaccine prioritization during the COVID-19 pandemic

Chapman, L. A. C., Shukla, P., Rodríguez-Barraquer, I., Shete, P. B., León, T. M., Bibbins-Domingo, K., Rutherford, G. W., Schechter, R. & Lo, N. C., 23/02/2022, In: Scientific Reports. 12, 12 p., 3055.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Drivers of Resistance in Uganda and Malawi (DRUM): a protocol for the evaluation of One-Health drivers of Extended Spectrum Beta Lactamase (ESBL) resistance in Low-Middle Income Countries (LMICs)

Cocker, D., Sammarro, M., Chidziwisano, K., Elviss, N., Jacob, S. T., Kajumbula, H., Mugisha, L., Musoke, D., Musicha, P., Roberts, A. P., Rowlingson, B., Singer, A. C., Byrne, R. L., Edwards, T., Lester, R., Wilson, C., Hollihead, B., Thomson, N., Jewell, C. P., Morse, T., & 1 othersFeasey, N., 15/02/2022, (E-pub ahead of print) In: Wellcome Open Research. 7, 13 p., 55.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Unexposed populations and potential COVID-19 hospitalisations and deaths in European countries as per data up to 21 November 2021

Chapman, L. A. C., Barnard, R. C., Russell, T. W., Abbott, S., Zandvoort, K. V., Davies, N. G. & Kucharski, A. J., 6/01/2022, In: Eurosurveillance. 27, 1, 8 p., 2101038.

Research output: Contribution to Journal/Magazine › Journal article › peer-review